IN186879B - - Google Patents

Info

Publication number
IN186879B
IN186879B IN3101DE1997A IN186879B IN 186879 B IN186879 B IN 186879B IN 3101DE1997 A IN3101DE1997 A IN 3101DE1997A IN 186879 B IN186879 B IN 186879B
Authority
IN
India
Application number
Other languages
English (en)
Inventor
Yatendra Kumar
Rajesh Kumar Thaper
S M Dileep Kumar
Jag Mohan Khanna
Original Assignee
Ranbaxy Lab Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ranbaxy Lab Ltd filed Critical Ranbaxy Lab Ltd
Priority to IN3101DE1997 priority Critical patent/IN186879B/en
Priority to US09/055,572 priority patent/US5939564A/en
Publication of IN186879B publication Critical patent/IN186879B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/30—Oxygen atoms, e.g. delta-lactones

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IN3101DE1997 1997-10-28 1997-10-28 IN186879B (id)

Priority Applications (2)

Application Number Priority Date Filing Date Title
IN3101DE1997 IN186879B (id) 1997-10-28 1997-10-28
US09/055,572 US5939564A (en) 1997-10-28 1998-04-06 Process of lactonization in the preparation of statins

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IN3101DE1997 IN186879B (id) 1997-10-28 1997-10-28

Publications (1)

Publication Number Publication Date
IN186879B true IN186879B (id) 2001-12-01

Family

ID=11092797

Family Applications (1)

Application Number Title Priority Date Filing Date
IN3101DE1997 IN186879B (id) 1997-10-28 1997-10-28

Country Status (2)

Country Link
US (1) US5939564A (id)
IN (1) IN186879B (id)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2388182A1 (en) 1999-10-27 2001-05-03 Merck & Co., Inc. Lactonization process
WO2001034590A1 (en) 1999-11-11 2001-05-17 Biocon India Limited Process for manufacturing simvastatin and the novel intermediates
US6573385B1 (en) 1999-11-11 2003-06-03 Biocon India Limited Process for manufacturing simvastatin and novel intermediates thereof
AU4183301A (en) 2000-03-03 2001-09-17 Biogal Gyogyszergyar A process for purifying lovastatin and simvastatin with reduced levels of dimeric impurities
NL1017548C2 (nl) 2001-03-09 2002-09-10 Synthon Bv Een lactonisatie proces.
WO2002094803A1 (en) * 2001-05-18 2002-11-28 Aurobindo Pharma Limited A process for lactonization to produce highly pure simvastatin
KR100423892B1 (ko) * 2001-12-03 2004-03-22 씨제이 주식회사 스타틴의 제조에 있어서 새로운 락톤화 방법
KR100435142B1 (ko) * 2002-01-09 2004-06-09 한미약품 주식회사 개선된 심바스타틴의 제조방법
US6603022B1 (en) 2002-05-10 2003-08-05 Biocon India Limited Process for manufacturing Simvastatin and novel intermediates thereof
US7777056B2 (en) * 2004-03-30 2010-08-17 Lupin Ltd. Method for manufacture of 4-hydroxy pyran-2-one derivatives
WO2007020079A2 (en) * 2005-08-17 2007-02-22 Synthon B.V. Orally disintegratable simvastatin tablets
US20090048335A1 (en) * 2007-08-17 2009-02-19 Venkata Naga Mandava Process for preparing simvastatin

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4820850A (en) * 1987-07-10 1989-04-11 Merck & Co., Inc. Process for α-C-alkylation of the 8-acyl group on mevinolin and analogs thereof
US4916239A (en) * 1988-07-19 1990-04-10 Merck & Co., Inc. Process for the lactonization of mevinic acids and analogs thereof

Also Published As

Publication number Publication date
US5939564A (en) 1999-08-17

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