IN184685B - - Google Patents

Info

Publication number
IN184685B
IN184685B IN294DE1996A IN184685B IN 184685 B IN184685 B IN 184685B IN 294DE1996 A IN294DE1996 A IN 294DE1996A IN 184685 B IN184685 B IN 184685B
Authority
IN
India
Application number
Other languages
English (en)
Inventor
Shaktin Upadhyay
D N K Sharma
Nalini Wali
N K Saraswathi
Suman Dhawan
Raman Prasad Yadav
Original Assignee
Nat Inst Immunology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nat Inst Immunology filed Critical Nat Inst Immunology
Priority to IN294DE1996 priority Critical patent/IN184685B/en
Priority to US08/789,464 priority patent/US6245781B1/en
Priority to US08/887,186 priority patent/US5856487A/en
Priority to US09/022,299 priority patent/US6291483B1/en
Priority to US09/304,415 priority patent/US6395772B1/en
Priority to IN937DE1999 priority patent/IN191811B/en
Publication of IN184685B publication Critical patent/IN184685B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
IN294DE1996 1996-02-14 1996-02-14 IN184685B (US20070202208A1-20070830-C00006.png)

Priority Applications (6)

Application Number Priority Date Filing Date Title
IN294DE1996 IN184685B (US20070202208A1-20070830-C00006.png) 1996-02-14 1996-02-14
US08/789,464 US6245781B1 (en) 1996-02-14 1997-01-27 Method for suppressing allogenic immune response or prevention/treatment of graft vs. host disease or graft rejection
US08/887,186 US5856487A (en) 1996-02-14 1997-07-02 Application of protoberberine alkaloid, berberine, an immunosuppressive agent
US09/022,299 US6291483B1 (en) 1996-02-14 1998-02-11 Methods for prevention and treatment of septic shock
US09/304,415 US6395772B1 (en) 1996-02-14 1999-05-03 Method for blocking endothelial cell-leukocyte attachment by inhibiting expression of adhesion molecules on the vascular endothelium for therapeutic applications
IN937DE1999 IN191811B (US20070202208A1-20070830-C00006.png) 1996-02-14 1999-06-30

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IN294DE1996 IN184685B (US20070202208A1-20070830-C00006.png) 1996-02-14 1996-02-14

Publications (1)

Publication Number Publication Date
IN184685B true IN184685B (US20070202208A1-20070830-C00006.png) 2000-09-23

Family

ID=11089150

Family Applications (2)

Application Number Title Priority Date Filing Date
IN294DE1996 IN184685B (US20070202208A1-20070830-C00006.png) 1996-02-14 1996-02-14
IN937DE1999 IN191811B (US20070202208A1-20070830-C00006.png) 1996-02-14 1999-06-30

Family Applications After (1)

Application Number Title Priority Date Filing Date
IN937DE1999 IN191811B (US20070202208A1-20070830-C00006.png) 1996-02-14 1999-06-30

Country Status (2)

Country Link
US (2) US6245781B1 (US20070202208A1-20070830-C00006.png)
IN (2) IN184685B (US20070202208A1-20070830-C00006.png)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8147824B2 (en) 1999-08-05 2012-04-03 Athersys, Inc. Immunomodulatory properties of multipotent adult progenitor cells and uses thereof
US7901713B2 (en) * 2001-06-20 2011-03-08 Metaproteomics, Llc Inhibition of COX-2 and/or 5-LOX activity by fractions isolated or derived from hops
US20040115290A1 (en) * 2001-06-20 2004-06-17 Tripp Matthew L. Modulation of inflammation by hops fractions and derivatives
US7666449B2 (en) * 2001-06-20 2010-02-23 Metaproteomics, Llc Anti-inflammatory pharmaceutical compositions for reducing inflammation and the treatment or prevention of gastric toxicity
US8142819B2 (en) 2002-10-21 2012-03-27 Metaproteomics, Llc Synergistic compositions that treat or inhibit pathological conditions associated with inflammatory response
US7901714B2 (en) * 2001-06-20 2011-03-08 Metaproteomics, Llp Treatment modalities for autoimmune diseases
US8206753B2 (en) * 2001-06-20 2012-06-26 Metaproteomics, Llc Anti-inflammatory botanical products for the treatment of metabolic syndrome and diabetes
US8168234B2 (en) * 2001-06-20 2012-05-01 Metaproteomics, Llc Compositions that treat or inhibit pathological conditions associated with inflammatory response
US6638981B2 (en) * 2001-08-17 2003-10-28 Epicept Corporation Topical compositions and methods for treating pain
US8158160B2 (en) 2001-11-13 2012-04-17 Eric Hauser Kuhrts Anti-inflammatory cyclooxygenase inhibitors
US20040071666A1 (en) * 2002-05-24 2004-04-15 The Regents Of The University Of Michigan Compositions and methods related to graft-versus-host disease
CN1324026C (zh) * 2002-09-23 2007-07-04 东北制药总厂 硫酸黄连素的制备方法
WO2004037180A2 (en) * 2002-10-21 2004-05-06 Metaproteomics, Llc Compositions that treat or inhibit pathological conditions associated with inflammatory response
WO2005039483A2 (en) 2003-05-22 2005-05-06 Metaproteomics, Llc Anti-inflammatory pharmaceutical compositions for reducing inflammation and the treatment or prevention of gastric toxicity
US20050192356A1 (en) * 2004-02-27 2005-09-01 Babish John G. Synergistic anti-inflammatory pharmaceutical compositions and methods of use
US7914831B2 (en) * 2004-02-27 2011-03-29 Metaproteomics, Llc Synergistic anti-inflammatory pharmaceutical compositions and related methods using curcuminoids or methylxanthines
NZ555219A (en) * 2004-11-13 2011-03-31 Metaproteomics Llc Compositions exhibiting inhibition of cyclooxygenase-2
EP1928248A4 (en) * 2005-08-09 2009-09-16 Metaproteomics Llp MODULATION OF KINASE PROTEINS USING HOP OR ACACIA PRODUCTS
US10117900B2 (en) 2005-11-09 2018-11-06 Athersys, Inc. MAPC treatment of brain injuries and diseases
US11000546B2 (en) 2005-11-09 2021-05-11 Athersys, Inc. Immunomodulatory properties of MAPCs and uses thereof
WO2007067812A2 (en) * 2005-12-09 2007-06-14 Metaproteomics, Llc Protein kinase modulation by hops and acacia products
CA3124132A1 (en) 2006-01-23 2007-08-02 Abt Holding Company Mapc therapeutics without adjunctive immunosuppressive treatment
US20080124404A1 (en) * 2006-06-19 2008-05-29 Jingwen Liu Hypolipidemic and/or hypocholesteremic compounds obtainable from the goldenseal plant
US20080051466A1 (en) * 2006-06-20 2008-02-28 Metaproteomics, Llc Isoalpha acid based protein kinase modulation cancer treatment
EP2043621A4 (en) * 2006-06-20 2009-08-26 Metaproteomics Llc TREATMENT OF CANCER BY MODULATION OF PROTEIN KINASE USING HEXAHYDRO-ISOALPHA ACIDS
CN100431542C (zh) * 2006-11-07 2008-11-12 暨南大学 育亨宾和小檗碱混合在制药中的应用
AU2008229110A1 (en) * 2007-03-19 2008-09-25 Metaproteomics, Llc Methods and compositions for promoting bone and joint health
CA2686043A1 (en) 2007-05-11 2008-11-20 Metaproteomics, Llc Methods and compositions for heavy metal detoxification
CN101969972A (zh) * 2007-12-10 2011-02-09 麦特普罗泰欧米克斯有限公司 癌症、血管生成、以及与其相关的炎症通路的取代的1,3-环戊二酮多靶点蛋白激酶调节剂
CA2716080C (en) 2008-02-20 2016-12-13 Targia Pharmaceuticals Cns pharmaceutical compositions and methods of use
US20100222262A1 (en) * 2008-04-02 2010-09-02 Metaproteomics, Llc Substituted 1, 3-cyclopentadione attenuated endothelial inflammation and endothelial-monocyte interactions
CN103181896B (zh) * 2011-12-30 2015-10-14 沈阳药科大学 一种含有小檗胺类药物的脂质体制剂及其制备方法
US10500169B2 (en) * 2014-09-17 2019-12-10 Xiu-Min Li Supression of IgE production by compounds derived from traditional chinese medicine
WO2016209036A2 (ko) * 2015-06-26 2016-12-29 한국생명공학연구원 타입 iii 에펙터 hopq1 및 lim 도메인 키나아제1(limk1)의 상호작용을 이용한 hopq1에 의한 면역 억제에 대한 억제제 스크리닝 방법 및 이를 위한 조성물
US20190335745A1 (en) * 2016-11-24 2019-11-07 Sigmadrugs Kutató Korlátolt Felelösségü Társaság Compositions for organ preservation
CN111053770B (zh) * 2019-12-23 2023-04-14 厦门大学 黄连素作为同种异体心脏移植中所使用的免疫抑制剂的应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07315051A (ja) * 1994-05-20 1995-12-05 Shuji Hashimoto 自動車乗降時の日除け雨除け用装置
JPH07316051A (ja) * 1994-05-23 1995-12-05 Kanegafuchi Chem Ind Co Ltd 免疫抑制剤としてのベルベリン

Also Published As

Publication number Publication date
US6291483B1 (en) 2001-09-18
IN191811B (US20070202208A1-20070830-C00006.png) 2004-01-03
US6245781B1 (en) 2001-06-12

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