IN163125B - - Google Patents

Info

Publication number
IN163125B
IN163125B IN291/MAS/86A IN291MA1986A IN163125B IN 163125 B IN163125 B IN 163125B IN 291MA1986 A IN291MA1986 A IN 291MA1986A IN 163125 B IN163125 B IN 163125B
Authority
IN
India
Application number
IN291/MAS/86A
Other languages
English (en)
Inventor
Sandor Hosztafi
Sandor Makleit
Kalman Zsupan
Laszlo Szilagyi
Original Assignee
Alkaloida Vegyeszeti Gyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from HU5685A external-priority patent/HU199901B/hu
Application filed by Alkaloida Vegyeszeti Gyar filed Critical Alkaloida Vegyeszeti Gyar
Publication of IN163125B publication Critical patent/IN163125B/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/485Morphinan derivatives, e.g. morphine, codeine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D221/00Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22Bridged ring systems
    • C07D221/28Morphinans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D489/00Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D489/00Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/06Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with a hetero atom directly attached in position 14
    • C07D489/08Oxygen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Emergency Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IN291/MAS/86A 1985-01-08 1986-04-18 IN163125B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HU5685A HU199901B (en) 1985-01-08 1985-01-08 Process for production of derivatives of hydrazon with morfinane carcass
DD86290095A DD258006A5 (de) 1985-01-08 1986-05-09 Verfahren zur herstellung von hydrozon-derivaten

Publications (1)

Publication Number Publication Date
IN163125B true IN163125B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1988-08-13

Family

ID=25748053

Family Applications (1)

Application Number Title Priority Date Filing Date
IN291/MAS/86A IN163125B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1985-01-08 1986-04-18

Country Status (4)

Country Link
EP (1) EP0242417B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPS62258380A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DD (1) DD258006A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IN (1) IN163125B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU208633B (en) * 1991-02-04 1993-12-28 Alkaloida Vegyeszeti Gyar Process for production of analgetic compositions as applicable for blocking of opioid-binding spaces /2-receptors/ causing respiration depression
AU666702B2 (en) * 1992-01-23 1996-02-22 Toray Industries, Inc. Morphinan derivative and medicinal use
AU686203B2 (en) 1993-07-23 1998-02-05 Toray Industries, Inc. Morphinan derivative and medicinal use
US7923454B2 (en) 2002-05-17 2011-04-12 Jenken Biosciences, Inc. Opioid and opioid-like compounds and uses thereof
US7501433B2 (en) 2002-05-17 2009-03-10 Jenken Biosciences, Inc. Opioid and opioid-like compounds and uses thereof
CN103405431B (zh) 2002-05-17 2016-04-13 台湾J药品有限公司 阿片和阿片样化合物及其用途
US8017622B2 (en) 2003-05-16 2011-09-13 Jenken Biosciences, Inc. Opioid and opioid-like compounds and uses thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1078467A (fr) * 1952-02-18 1954-11-18 Merck & Co Inc Procédé de synthèse totale de la morphine
US2797221A (en) * 1954-06-22 1957-06-25 Merck & Co Inc Process and intermediates for producing 1-bromocodeinone
US4608376A (en) * 1981-10-16 1986-08-26 Carolyn McGinnis Opiate agonists and antagonists
CA1258674A (en) * 1981-10-16 1989-08-22 Sloan-Kettering Institute For Cancer Research Opiate agonists and antagonists

Also Published As

Publication number Publication date
DD258006A5 (de) 1988-07-06
EP0242417A1 (en) 1987-10-28
JPS62258380A (ja) 1987-11-10
EP0242417B1 (en) 1993-02-10

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