IL91581A0 - Methods for preparing captopril and its analogues - Google Patents

Methods for preparing captopril and its analogues

Info

Publication number
IL91581A0
IL91581A0 IL91581A IL9158189A IL91581A0 IL 91581 A0 IL91581 A0 IL 91581A0 IL 91581 A IL91581 A IL 91581A IL 9158189 A IL9158189 A IL 9158189A IL 91581 A0 IL91581 A0 IL 91581A0
Authority
IL
Israel
Prior art keywords
analogues
methods
captopril
preparing
preparing captopril
Prior art date
Application number
IL91581A
Other versions
IL91581A (en
Original Assignee
Sepracor Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sepracor Inc filed Critical Sepracor Inc
Publication of IL91581A0 publication Critical patent/IL91581A0/en
Publication of IL91581A publication Critical patent/IL91581A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/04—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
IL91581A 1988-09-13 1989-09-08 Methods for preparing optically active captopril and its analogues IL91581A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US24420388A 1988-09-13 1988-09-13

Publications (2)

Publication Number Publication Date
IL91581A0 true IL91581A0 (en) 1990-04-29
IL91581A IL91581A (en) 1993-07-08

Family

ID=22921794

Family Applications (1)

Application Number Title Priority Date Filing Date
IL91581A IL91581A (en) 1988-09-13 1989-09-08 Methods for preparing optically active captopril and its analogues

Country Status (5)

Country Link
EP (1) EP0434743A4 (en)
JP (1) JPH04500673A (en)
AU (1) AU4304789A (en)
IL (1) IL91581A (en)
WO (1) WO1990002732A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU208954B (en) * 1990-09-21 1994-02-28 Egyt Gyogyszervegyeszeti Gyar Process for producing 1-(3-mercapto-(2s)-methyl-1-oxo-propyl)-l-prolyn
US5026873A (en) * 1989-11-06 1991-06-25 E. R. Squibb & Sons, Inc. Process for direct isolation of captopril

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4105776A (en) * 1976-06-21 1978-08-08 E. R. Squibb & Sons, Inc. Proline derivatives and related compounds
US4046889A (en) * 1976-02-13 1977-09-06 E. R. Squibb & Sons, Inc. Azetidine-2-carboxylic acid derivatives
IT7851510A0 (en) * 1977-10-28 1978-10-16 Sandoz Ag AMIDES OF CYCLIC AMINO ACIDS THEIR PREPARATION AND THEIR APPLICATION AS MEDICINES
US4154934A (en) * 1978-08-11 1979-05-15 E. R. Squibb & Sons, Inc. Mercaptoacylamino derivatives of heterocyclic carboxylic acids
US4297282A (en) * 1979-03-02 1981-10-27 Sumitomo Chemical Company, Limited Resolution of mercaptopropionic acids
US4288368A (en) * 1979-07-30 1981-09-08 E. R. Squibb & Sons, Inc. Dithioacylproline derivatives
HU184082B (en) * 1979-12-29 1984-06-28 Egyt Gyogyszervegyeszeti Gyar Process for preparing 1-3-/3mercapto-/2s/-methyl-propinyl/-pyrrolidine-/2s/-carboxylic acid
IE50839B1 (en) * 1980-02-26 1986-07-23 Wyeth John & Brother Ltd Novel processes for preparing proline derivatives and analogous compounds

Also Published As

Publication number Publication date
JPH04500673A (en) 1992-02-06
AU4304789A (en) 1990-04-02
EP0434743A1 (en) 1991-07-03
EP0434743A4 (en) 1991-09-25
IL91581A (en) 1993-07-08
WO1990002732A1 (en) 1990-03-22

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Legal Events

Date Code Title Description
KB Patent renewed
KB Patent renewed
RH1 Patent not in force