IL91047A - Zinc complexes for the treatment of free radical- induced diseases - Google Patents
Zinc complexes for the treatment of free radical- induced diseasesInfo
- Publication number
- IL91047A IL91047A IL91047A IL9104789A IL91047A IL 91047 A IL91047 A IL 91047A IL 91047 A IL91047 A IL 91047A IL 9104789 A IL9104789 A IL 9104789A IL 91047 A IL91047 A IL 91047A
- Authority
- IL
- Israel
- Prior art keywords
- treatment
- free radical
- zinc complexes
- induced diseases
- zinc
- Prior art date
Links
- 201000010099 disease Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 150000003751 zinc Chemical class 0.000 title 1
- LJRDOKAZOAKLDU-UDXJMMFXSA-N (2s,3s,4r,5r,6r)-5-amino-2-(aminomethyl)-6-[(2r,3s,4r,5s)-5-[(1r,2r,3s,5r,6s)-3,5-diamino-2-[(2s,3r,4r,5s,6r)-3-amino-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-6-hydroxycyclohexyl]oxy-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]oxyoxane-3,4-diol;sulfuric ac Chemical compound OS(O)(=O)=O.N[C@@H]1[C@@H](O)[C@H](O)[C@H](CN)O[C@@H]1O[C@H]1[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](N)C[C@@H](N)[C@@H]2O)O[C@@H]2[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O2)N)O[C@@H]1CO LJRDOKAZOAKLDU-UDXJMMFXSA-N 0.000 abstract 1
- UBQYURCVBFRUQT-UHFFFAOYSA-N N-benzoyl-Ferrioxamine B Chemical compound CC(=O)N(O)CCCCCNC(=O)CCC(=O)N(O)CCCCCNC(=O)CCC(=O)N(O)CCCCCN UBQYURCVBFRUQT-UHFFFAOYSA-N 0.000 abstract 1
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 229960000958 deferoxamine Drugs 0.000 abstract 1
- 229960001639 penicillamine Drugs 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000011701 zinc Substances 0.000 abstract 1
- 229910052725 zinc Inorganic materials 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/30—Zinc; Compounds thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
- C07C259/04—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
- C07C259/06—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to hydrogen atoms or to acyclic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Inorganic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Paper (AREA)
Priority Applications (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IL91047A IL91047A (en) | 1989-07-19 | 1989-07-19 | Zinc complexes for the treatment of free radical- induced diseases |
| ES90307400T ES2062375T3 (es) | 1989-07-19 | 1990-07-06 | Composiciones farmaceuticas que contienen un complejo de zinc. |
| DE69006654T DE69006654T2 (de) | 1989-07-19 | 1990-07-06 | Einen Zink-Komplex enthaltende Arzneimittel. |
| EP90307400A EP0409452B1 (de) | 1989-07-19 | 1990-07-06 | Einen Zink-Komplex enthaltende Arzneimittel |
| AT90307400T ATE101594T1 (de) | 1989-07-19 | 1990-07-06 | Einen zink-komplex enthaltende arzneimittel. |
| US07/550,462 US5075469A (en) | 1989-07-19 | 1990-07-10 | Pharmaceutical compositions containing a zinc complex |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IL91047A IL91047A (en) | 1989-07-19 | 1989-07-19 | Zinc complexes for the treatment of free radical- induced diseases |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL91047A0 IL91047A0 (en) | 1990-02-09 |
| IL91047A true IL91047A (en) | 1993-06-10 |
Family
ID=11060194
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL91047A IL91047A (en) | 1989-07-19 | 1989-07-19 | Zinc complexes for the treatment of free radical- induced diseases |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US5075469A (de) |
| EP (1) | EP0409452B1 (de) |
| AT (1) | ATE101594T1 (de) |
| DE (1) | DE69006654T2 (de) |
| ES (1) | ES2062375T3 (de) |
| IL (1) | IL91047A (de) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX12394A (es) * | 1987-07-23 | 1993-12-01 | Ciba Geigy Ag | Procedimiento par la obtencion de carbamatos de polietilenglicol. |
| IL106064A (en) * | 1993-06-18 | 1997-11-20 | Yissum Res Dev Co | Gallium complexes for the treatment of free radical-induced diseases |
| US5637311A (en) * | 1995-06-29 | 1997-06-10 | Procyte Corporation | Zinc(II) complexes and methods related thereto |
| US7026116B1 (en) * | 1996-04-04 | 2006-04-11 | Bio-Rad Laboratories, Inc. | Polymorphisms in the region of the human hemochromatosis gene |
| US6140305A (en) * | 1996-04-04 | 2000-10-31 | Bio-Rad Laboratories, Inc. | Hereditary hemochromatosis gene products |
| US6849399B1 (en) | 1996-05-23 | 2005-02-01 | Bio-Rad Laboratories, Inc. | Methods and compositions for diagnosis and treatment of iron misregulation diseases |
| AU745403B2 (en) | 1997-06-13 | 2002-03-21 | Bio-Rad Laboratories, Inc. | Methods and compositions for diagnosis and treatment of iron overload diseases and iron deficiency diseases |
| US7687650B2 (en) | 2006-02-03 | 2010-03-30 | Jr Chem, Llc | Chemical compositions and methods of making them |
| AU2006337161B2 (en) | 2006-02-03 | 2012-06-07 | Obagi Cosmeceuticals Llc | Anti-aging treatment using copper and zinc compositions |
| US7897800B2 (en) | 2006-02-03 | 2011-03-01 | Jr Chem, Llc | Chemical compositions and methods of making them |
| US7867522B2 (en) | 2006-09-28 | 2011-01-11 | Jr Chem, Llc | Method of wound/burn healing using copper-zinc compositions |
| US8273791B2 (en) | 2008-01-04 | 2012-09-25 | Jr Chem, Llc | Compositions, kits and regimens for the treatment of skin, especially décolletage |
| US20160184354A1 (en) | 2009-01-23 | 2016-06-30 | Jr Chem, Llc | Rosacea treatments and kits for performing them |
| BR112012003447A2 (pt) * | 2009-08-19 | 2018-03-20 | Hadasit Med Res Service | método de prevenir, tratar, melhorar ou inibir uma desordem relacionada ao sistema imunológico, uso de uma quantidade terapeuticamente eficaz de pelo menos um complexo de metal desferrioxamina (complexo de metal-dfo), composição e composição farmacêutica. |
| US8952057B2 (en) | 2011-01-11 | 2015-02-10 | Jr Chem, Llc | Compositions for anorectal use and methods for treating anorectal disorders |
| US11331287B2 (en) | 2013-06-06 | 2022-05-17 | Balchem Corporation | Iron supplement |
| AU2015369552B2 (en) | 2014-12-22 | 2020-11-19 | Eduard Berenshtein | New metal complexes of nocardamine and their use in pharmaceutical compositions |
| SG11201806157WA (en) | 2016-02-11 | 2018-08-30 | Mordechai Chevion | Method and pharmaceutical composition for treatment of neurodegeneration |
| EP3781143A4 (de) * | 2018-04-15 | 2022-01-05 | Mordechai Chevion | Zusammensetzungen und verfahren zur behandlung von eisenüberlastung |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2554690A (en) * | 1944-06-13 | 1951-05-29 | Squibb & Sons Inc | Zinc-penicillin and preparation thereof |
| US3297531A (en) * | 1963-12-11 | 1967-01-10 | Ernst A H Friedheim | Complexes of trivalent antimony with penicillamine, and admixtures of excess penicillamine with said complexes |
| EP0325559B1 (de) * | 1988-01-20 | 1993-12-15 | Ciba-Geigy Ag | Verfahren zur Herstellung von Komplexverbindungen |
-
1989
- 1989-07-19 IL IL91047A patent/IL91047A/xx not_active IP Right Cessation
-
1990
- 1990-07-06 ES ES90307400T patent/ES2062375T3/es not_active Expired - Lifetime
- 1990-07-06 EP EP90307400A patent/EP0409452B1/de not_active Expired - Lifetime
- 1990-07-06 AT AT90307400T patent/ATE101594T1/de active
- 1990-07-06 DE DE69006654T patent/DE69006654T2/de not_active Expired - Fee Related
- 1990-07-10 US US07/550,462 patent/US5075469A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP0409452A1 (de) | 1991-01-23 |
| ATE101594T1 (de) | 1994-03-15 |
| US5075469A (en) | 1991-12-24 |
| IL91047A0 (en) | 1990-02-09 |
| ES2062375T3 (es) | 1994-12-16 |
| EP0409452B1 (de) | 1994-02-16 |
| DE69006654D1 (de) | 1994-03-24 |
| DE69006654T2 (de) | 1994-05-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RH | Patent void |