IL90184A0 - Functionalized peptidyl aminodiols and-triols - Google Patents

Functionalized peptidyl aminodiols and-triols

Info

Publication number
IL90184A0
IL90184A0 IL90184A IL9018489A IL90184A0 IL 90184 A0 IL90184 A0 IL 90184A0 IL 90184 A IL90184 A IL 90184A IL 9018489 A IL9018489 A IL 9018489A IL 90184 A0 IL90184 A0 IL 90184A0
Authority
IL
Israel
Prior art keywords
aminodiols
peptidyl
triols
functionalized
peptidyl aminodiols
Prior art date
Application number
IL90184A
Other languages
English (en)
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Publication of IL90184A0 publication Critical patent/IL90184A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06191—Dipeptides containing heteroatoms different from O, S, or N
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0227—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the (partial) peptide sequence -Phe-His-NH-(X)2-C(=0)-, e.g. Renin-inhibitors with n = 2 - 6; for n > 6 see C07K5/06 - C07K5/10
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06078—Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL90184A 1988-05-09 1989-05-04 Functionalized peptidyl aminodiols and-triols IL90184A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US19273788A 1988-05-09 1988-05-09

Publications (1)

Publication Number Publication Date
IL90184A0 true IL90184A0 (en) 1989-12-15

Family

ID=22710858

Family Applications (1)

Application Number Title Priority Date Filing Date
IL90184A IL90184A0 (en) 1988-05-09 1989-05-04 Functionalized peptidyl aminodiols and-triols

Country Status (4)

Country Link
EP (1) EP0341602A2 (fr)
AU (1) AU3737889A (fr)
IL (1) IL90184A0 (fr)
WO (1) WO1989010751A1 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3839559A1 (de) * 1988-11-24 1990-05-31 Hoechst Ag Renin-hemmende aminodiol-derivate
EP0391180A3 (fr) * 1989-04-04 1991-04-03 F. Hoffmann-La Roche Ag Dérivés peptidiques d'acides aminés avec effet inhibiteur de la rénine
US5182266A (en) * 1990-01-31 1993-01-26 Abbott Laboratories Method for treating renal disease
IL96942A (en) * 1990-01-31 1995-01-24 Abbott Lab A pharmaceutical mixture containing a history of amide prevents renin
DE4126485A1 (de) * 1991-08-10 1993-02-11 Bayer Ag Trifluormethyl-haltige pseudopeptide
IL108924A0 (en) * 1993-03-19 1994-06-24 Ciba Vision Ag Compositions for the treatment of eye diseases

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4645759A (en) * 1984-06-22 1987-02-24 Abbott Laboratories Renin inhibiting compounds
US4652551A (en) * 1984-06-22 1987-03-24 Abbott Laboratories Renin inhibiting compounds
US4680284A (en) * 1985-01-23 1987-07-14 Abbott Laboratories Modified phenylalanine peptidylaminodiols
US4725583A (en) * 1985-01-23 1988-02-16 Abbott Laboratories Functionalized peptidylaminoalcohols
US4837204A (en) * 1985-01-23 1989-06-06 Abbott Laboratories Functionalized peptidyl aminodiols and -triols
US4826815A (en) * 1985-05-17 1989-05-02 Abbott Laboratories Renin inhibiting compounds
US4725584A (en) * 1986-02-19 1988-02-16 Abbott Laboratories Peptidyl-1-amino-2,4-diols

Also Published As

Publication number Publication date
WO1989010751A1 (fr) 1989-11-16
EP0341602A2 (fr) 1989-11-15
AU3737889A (en) 1989-11-29

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