IL89968A - 4-oxo quinazoline derivatives, processes for their preparation and pharmaceutical compositions comprising them - Google Patents
4-oxo quinazoline derivatives, processes for their preparation and pharmaceutical compositions comprising themInfo
- Publication number
- IL89968A IL89968A IL89968A IL8996889A IL89968A IL 89968 A IL89968 A IL 89968A IL 89968 A IL89968 A IL 89968A IL 8996889 A IL8996889 A IL 8996889A IL 89968 A IL89968 A IL 89968A
- Authority
- IL
- Israel
- Prior art keywords
- processes
- preparation
- pharmaceutical compositions
- quinazoline derivatives
- oxo quinazoline
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
- C07D239/88—Oxygen atoms
- C07D239/90—Oxygen atoms with acyclic radicals attached in position 2 or 3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
- C07D239/88—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
- C07D239/96—Two oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB888809978A GB8809978D0 (en) | 1988-04-27 | 1988-04-27 | Anti-tumour agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL89968A true IL89968A (en) | 1993-01-31 |
Family
ID=10635961
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL89968A IL89968A (en) | 1988-04-27 | 1989-04-14 | 4-oxo quinazoline derivatives, processes for their preparation and pharmaceutical compositions comprising them |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US4985441A (de) |
| EP (1) | EP0339976B1 (de) |
| JP (1) | JPH01313469A (de) |
| AU (1) | AU626541B2 (de) |
| DE (1) | DE68912818T2 (de) |
| DK (1) | DK202989A (de) |
| FI (1) | FI892015A (de) |
| GB (2) | GB8809978D0 (de) |
| IL (1) | IL89968A (de) |
| NO (1) | NO891723L (de) |
| NZ (1) | NZ228812A (de) |
| PT (1) | PT90375B (de) |
| ZA (1) | ZA892836B (de) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8727737D0 (en) * | 1987-11-26 | 1987-12-31 | Ici Plc | Antitumour agents |
| GB8829296D0 (en) * | 1988-12-15 | 1989-01-25 | Ici Plc | Anti-tumour compounds |
| US5286726A (en) * | 1990-04-12 | 1994-02-15 | The Regents Of The University Of Michigan | Difluoroglutamic acid conjugates with folates and anti-folates for the treatment of neoplastic diseases |
| ZA913730B (en) * | 1990-05-30 | 1992-02-26 | Ici Plc | Anti-tumor compounds |
| GB9105771D0 (en) * | 1991-03-19 | 1991-05-01 | Cancer Res Inst Royal | Anti-cancer compounds |
| GB9205907D0 (en) * | 1992-03-18 | 1992-04-29 | Cancer Res Inst Royal | Anti-cancer compounds |
| US5430148A (en) * | 1992-03-31 | 1995-07-04 | Agouron Pharmaceuticals, Inc. | Antiproliferative quinazolines |
| US5753664A (en) * | 1995-03-16 | 1998-05-19 | Takeda Chemical Industries, Ltd. | Heterocyclic compounds, their production and use |
| GB9904275D0 (en) | 1999-02-24 | 1999-04-21 | Cancer Res Campaign Tech | Anti-cancer compounds |
| TWI490444B (zh) * | 2009-01-23 | 2015-07-01 | Univ Nat Taipei Technology | 線型多波長共焦顯微方法與系統 |
| PT2445502T (pt) | 2009-06-25 | 2017-09-22 | Alkermes Pharma Ireland Ltd | Compostos heterocíclicos para o tratamento de distúrbios neurológicos e psicológicos |
| AU2019230014A1 (en) | 2018-03-05 | 2020-09-17 | Alkermes Pharma Ireland Limited | Aripiprazole dosing strategy |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3069468D1 (en) * | 1979-12-19 | 1984-11-22 | Nat Res Dev | Quinazoline derivatives, processes for their preparation, compositions containing them and their use as anti-cancer agents |
| GB8513754D0 (en) * | 1985-05-31 | 1985-07-03 | Jones T R | Anti-cancer quinazoline derivatives |
| GB8607683D0 (en) * | 1986-03-27 | 1986-04-30 | Ici Plc | Anti-tumor agents |
| GB8707053D0 (en) * | 1987-03-25 | 1987-04-29 | Ici Plc | Anti-tumour agents |
| US4857530A (en) * | 1987-11-03 | 1989-08-15 | Warner-Lambert Company | Substituted quinazolinones as anticancer agents |
| GB8829296D0 (en) * | 1988-12-15 | 1989-01-25 | Ici Plc | Anti-tumour compounds |
-
1988
- 1988-04-27 GB GB888809978A patent/GB8809978D0/en active Pending
-
1989
- 1989-04-07 GB GB8907923A patent/GB2217709B/en not_active Expired - Fee Related
- 1989-04-14 IL IL89968A patent/IL89968A/xx unknown
- 1989-04-18 ZA ZA892836A patent/ZA892836B/xx unknown
- 1989-04-19 NZ NZ228812A patent/NZ228812A/xx unknown
- 1989-04-24 AU AU33376/89A patent/AU626541B2/en not_active Ceased
- 1989-04-26 PT PT90375A patent/PT90375B/pt not_active IP Right Cessation
- 1989-04-26 DK DK202989A patent/DK202989A/da not_active Application Discontinuation
- 1989-04-26 EP EP89304166A patent/EP0339976B1/de not_active Expired - Lifetime
- 1989-04-26 NO NO89891723A patent/NO891723L/no unknown
- 1989-04-26 DE DE68912818T patent/DE68912818T2/de not_active Expired - Fee Related
- 1989-04-27 FI FI892015A patent/FI892015A/fi not_active Application Discontinuation
- 1989-04-27 JP JP1106115A patent/JPH01313469A/ja active Pending
-
1990
- 1990-04-03 US US07/504,740 patent/US4985441A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| DK202989D0 (da) | 1989-04-26 |
| EP0339976B1 (de) | 1994-02-02 |
| PT90375B (pt) | 1994-09-30 |
| NO891723L (no) | 1989-10-30 |
| GB8907923D0 (en) | 1989-05-24 |
| GB2217709A (en) | 1989-11-01 |
| AU3337689A (en) | 1989-11-02 |
| FI892015A (fi) | 1989-10-28 |
| NZ228812A (en) | 1991-08-27 |
| DE68912818D1 (de) | 1994-03-17 |
| US4985441A (en) | 1991-01-15 |
| DK202989A (da) | 1989-10-28 |
| EP0339976A1 (de) | 1989-11-02 |
| AU626541B2 (en) | 1992-08-06 |
| NO891723D0 (no) | 1989-04-26 |
| ZA892836B (en) | 1989-12-27 |
| FI892015A0 (fi) | 1989-04-27 |
| DE68912818T2 (de) | 1994-05-19 |
| PT90375A (pt) | 1989-11-10 |
| GB2217709B (en) | 1992-04-15 |
| GB8809978D0 (en) | 1988-06-02 |
| JPH01313469A (ja) | 1989-12-18 |
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