IL85627A - Pharmaceutical compositions for treatment of disorders of ischemic origin comprising metformin and its salts - Google Patents

Pharmaceutical compositions for treatment of disorders of ischemic origin comprising metformin and its salts

Info

Publication number
IL85627A
IL85627A IL85627A IL8562788A IL85627A IL 85627 A IL85627 A IL 85627A IL 85627 A IL85627 A IL 85627A IL 8562788 A IL8562788 A IL 8562788A IL 85627 A IL85627 A IL 85627A
Authority
IL
Israel
Prior art keywords
metformin
salts
treatment
disorders
pharmaceutical compositions
Prior art date
Application number
IL85627A
Other versions
IL85627A0 (en
Original Assignee
Lipha
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lipha filed Critical Lipha
Publication of IL85627A0 publication Critical patent/IL85627A0/en
Publication of IL85627A publication Critical patent/IL85627A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

The invention relates to the use of metformin and its salts in the preparation of medicaments. This derivative is used in the preparation of medicaments manifesting anti-ischaemic and antianoxic properties. It is also employed in the preparation of medicaments intended for the treatment or regression of neovascularisation.
IL85627A 1987-03-06 1988-03-03 Pharmaceutical compositions for treatment of disorders of ischemic origin comprising metformin and its salts IL85627A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8703028A FR2611500B1 (en) 1987-03-06 1987-03-06 USE OF BIGUANIDE DERIVATIVES IN THE PREPARATION OF MEDICINES

Publications (2)

Publication Number Publication Date
IL85627A0 IL85627A0 (en) 1988-08-31
IL85627A true IL85627A (en) 1993-01-14

Family

ID=9348653

Family Applications (1)

Application Number Title Priority Date Filing Date
IL85627A IL85627A (en) 1987-03-06 1988-03-03 Pharmaceutical compositions for treatment of disorders of ischemic origin comprising metformin and its salts

Country Status (10)

Country Link
EP (1) EP0283369B1 (en)
JP (1) JPH0818978B2 (en)
AT (1) ATE98120T1 (en)
AU (1) AU610134B2 (en)
CA (1) CA1328606C (en)
DE (1) DE3886075T2 (en)
DK (1) DK169713B1 (en)
FR (1) FR2611500B1 (en)
IL (1) IL85627A (en)
ZA (1) ZA881540B (en)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5100919A (en) * 1984-03-19 1992-03-31 The Rockefeller University Biguanides and derivatives thereof as inhibitors of advanced glycosylation of a target protein
US5356913A (en) * 1990-02-09 1994-10-18 The Upjohn Company Use of insulin sensitizing agents to treat hypertension
WO1991012003A1 (en) * 1990-02-09 1991-08-22 The Upjohn Company Use of insulin sensitizing agents to treat hypertension
DE4432757A1 (en) * 1994-09-14 1996-03-21 Boehringer Mannheim Gmbh Pharmaceutical preparation containing metformin and process for its preparation
AU3631795A (en) * 1994-09-15 1996-03-29 Pharmagenesis, Inc. Composition and method for immunotherapy
JP4278863B2 (en) * 1997-12-08 2009-06-17 ブリストル−マイヤーズ スクイブ カンパニー Novel salt and method of metformin
US6099859A (en) 1998-03-20 2000-08-08 Andrx Pharmaceuticals, Inc. Controlled release oral tablet having a unitary core
JP4606582B2 (en) * 1998-04-29 2011-01-05 大日本住友製薬株式会社 Biguanide drugs for internal use
AU3536299A (en) * 1998-04-29 1999-11-16 Sumitomo Pharmaceuticals Company, Limited Oral formulation comprising biguanide and an organic acid
DE69831940T2 (en) * 1998-07-30 2006-04-20 Merck Santé Tablet with prolonged release of active ingredient in the stomach
US6099862A (en) 1998-08-31 2000-08-08 Andrx Corporation Oral dosage form for the controlled release of a biguanide and sulfonylurea
FR2796551B1 (en) * 1999-07-23 2003-07-25 Lipha NOVEL METFORMIN SALTS, PROCESS FOR OBTAINING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME
FR2796940B1 (en) * 1999-07-26 2005-04-08 Lipha NOVEL METFORMIN SALTS, PROCESS FOR OBTAINING THEM AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME
FR2809310B1 (en) * 2000-05-26 2004-02-13 Centre Nat Rech Scient USE OF BIGUANIDE DERIVATIVES FOR MANUFACTURING A MEDICINAL PRODUCT HAVING A HEALING EFFECT
WO2002012177A1 (en) * 2000-08-03 2002-02-14 Igor Anatolievich Pomytkin Composition of metformin with succinic acid or salts thereof and method for treating diabetes
US7959946B2 (en) 2002-09-20 2011-06-14 Watson Pharmaceuticals, Inc. Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative
US8084058B2 (en) 2002-09-20 2011-12-27 Watson Pharmaceuticals, Inc. Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative
US9060941B2 (en) 2002-09-20 2015-06-23 Actavis, Inc. Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative
US7785627B2 (en) 2002-09-20 2010-08-31 Watson Pharmaceuticals, Inc. Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative
EP1945190A1 (en) * 2005-09-22 2008-07-23 Swissco Devcelopment AG Effervescent metformin composition and tablets and granules made therefrom
US8058312B2 (en) 2007-01-29 2011-11-15 Hanall Biopharma Co., Ltd. N, N-dimethyl imidodicarbonimidic diamide acetate, method for producing the same and pharmaceutical compositions comprising the same
GR1007299B (en) * 2010-03-24 2011-06-06 Uni - Pharma Κλεων Τσετης Φαρμακευτικα Εργαστηρια Αβεε Με Δ.Τ. Uni-Pharma Αβεε, Original effervescent hydrochloric metformin composition in the form of tablets

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2448448A (en) * 1942-06-08 1948-08-31 Courtaulds Ltd Dyeing of textile fibers containing nitrogen

Also Published As

Publication number Publication date
AU610134B2 (en) 1991-05-16
ZA881540B (en) 1988-08-26
DK169713B1 (en) 1995-01-23
IL85627A0 (en) 1988-08-31
JPH0818978B2 (en) 1996-02-28
ATE98120T1 (en) 1993-12-15
EP0283369A2 (en) 1988-09-21
DK116788A (en) 1988-09-07
CA1328606C (en) 1994-04-19
FR2611500A1 (en) 1988-09-09
FR2611500B1 (en) 1990-05-04
DE3886075T2 (en) 1994-04-14
DE3886075D1 (en) 1994-01-20
EP0283369A3 (en) 1989-11-29
AU1272788A (en) 1988-09-08
EP0283369B1 (en) 1993-12-08
JPS63230628A (en) 1988-09-27
DK116788D0 (en) 1988-03-04

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Legal Events

Date Code Title Description
KB Patent renewed
HP Change in proprietorship
KB Patent renewed
EXP Patent expired