IL85257A - Pharmaceutical compositions containing 2-(4-methoxyphenyl) 3-acetoxy-5-- (2-(dimethylamino) ethyl) -8-chloro-2,3- dihydro-1,5-benzothiazepin -4 (5h)-one having renal function-improving effect and diuretic effect - Google Patents
Pharmaceutical compositions containing 2-(4-methoxyphenyl) 3-acetoxy-5-- (2-(dimethylamino) ethyl) -8-chloro-2,3- dihydro-1,5-benzothiazepin -4 (5h)-one having renal function-improving effect and diuretic effectInfo
- Publication number
- IL85257A IL85257A IL85257A IL8525788A IL85257A IL 85257 A IL85257 A IL 85257A IL 85257 A IL85257 A IL 85257A IL 8525788 A IL8525788 A IL 8525788A IL 85257 A IL85257 A IL 85257A
- Authority
- IL
- Israel
- Prior art keywords
- effect
- renal function
- benzothiazepin
- acetoxy
- methoxyphenyl
- Prior art date
Links
- 208000004880 Polyuria Diseases 0.000 title abstract 3
- 230000001882 diuretic effect Effects 0.000 title abstract 3
- 230000000694 effects Effects 0.000 title abstract 3
- GYKFWCDBQAFCLJ-UHFFFAOYSA-N clentiazem Chemical compound C1=CC(OC)=CC=C1C1C(OC(C)=O)C(=O)N(CCN(C)C)C2=CC=C(Cl)C=C2S1 GYKFWCDBQAFCLJ-UHFFFAOYSA-N 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- External Artificial Organs (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2939687 | 1987-02-10 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL85257A0 IL85257A0 (en) | 1988-07-31 |
| IL85257A true IL85257A (en) | 1993-02-21 |
Family
ID=12274977
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL85257A IL85257A (en) | 1987-02-10 | 1988-01-29 | Pharmaceutical compositions containing 2-(4-methoxyphenyl) 3-acetoxy-5-- (2-(dimethylamino) ethyl) -8-chloro-2,3- dihydro-1,5-benzothiazepin -4 (5h)-one having renal function-improving effect and diuretic effect |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US4822789A (de) |
| EP (1) | EP0278449B1 (de) |
| KR (1) | KR930010583B1 (de) |
| AT (1) | ATE81007T1 (de) |
| AU (1) | AU603421B2 (de) |
| CA (1) | CA1300024C (de) |
| DE (1) | DE3874900T2 (de) |
| DK (1) | DK67288A (de) |
| IL (1) | IL85257A (de) |
| PH (1) | PH24727A (de) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL85257A (en) * | 1987-02-10 | 1993-02-21 | Tanabe Seiyaku Co | Pharmaceutical compositions containing 2-(4-methoxyphenyl) 3-acetoxy-5-- (2-(dimethylamino) ethyl) -8-chloro-2,3- dihydro-1,5-benzothiazepin -4 (5h)-one having renal function-improving effect and diuretic effect |
| CA2061353A1 (en) * | 1991-02-26 | 1992-08-27 | Sakae Murata | Prophylactic and curing agent for sequelae of cerebral neurocyte dyscrasia |
| EP0777661A1 (de) * | 1994-07-15 | 1997-06-11 | Loma Linda University Medical Center | Natriuretische und antihypertensive verbindungen |
| CN102183656B (zh) * | 2003-03-27 | 2014-04-16 | 儿童医院医疗中心 | 用于检测肾小管细胞损伤的早发的方法和试剂盒 |
| US20070037232A1 (en) * | 2005-03-31 | 2007-02-15 | Barasch Jonathan M | Detection of NGAL in chronic renal disease |
| US9205577B2 (en) * | 2010-02-05 | 2015-12-08 | Allergan, Inc. | Porogen compositions, methods of making and uses |
| US9138309B2 (en) | 2010-02-05 | 2015-09-22 | Allergan, Inc. | Porous materials, methods of making and uses |
| US11202853B2 (en) * | 2010-05-11 | 2021-12-21 | Allergan, Inc. | Porogen compositions, methods of making and uses |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3562257A (en) * | 1967-10-28 | 1971-02-09 | Tanabe Seiyaku Co | Benzothiazepine derivatives |
| US4567175A (en) * | 1983-06-03 | 1986-01-28 | Tanabe Seiyaku Co., Ltd. | 8-Chloro-1,5-benzothiazepine derivatives |
| GB2154577A (en) * | 1984-02-18 | 1985-09-11 | Tanabe Seiyaku Co | 1,5-benzothiazepines |
| GB2154578A (en) * | 1984-02-18 | 1985-09-11 | Tanabe Seiyaku Co | Novel 1,5-benzothiazepine derivatives and processes for preparing the same |
| IL85257A (en) * | 1987-02-10 | 1993-02-21 | Tanabe Seiyaku Co | Pharmaceutical compositions containing 2-(4-methoxyphenyl) 3-acetoxy-5-- (2-(dimethylamino) ethyl) -8-chloro-2,3- dihydro-1,5-benzothiazepin -4 (5h)-one having renal function-improving effect and diuretic effect |
-
1988
- 1988-01-29 IL IL85257A patent/IL85257A/xx not_active IP Right Cessation
- 1988-02-01 US US07/150,619 patent/US4822789A/en not_active Expired - Fee Related
- 1988-02-08 AT AT88101785T patent/ATE81007T1/de not_active IP Right Cessation
- 1988-02-08 DE DE8888101785T patent/DE3874900T2/de not_active Expired - Fee Related
- 1988-02-08 EP EP88101785A patent/EP0278449B1/de not_active Expired - Lifetime
- 1988-02-08 CA CA000558383A patent/CA1300024C/en not_active Expired - Lifetime
- 1988-02-09 PH PH36474A patent/PH24727A/en unknown
- 1988-02-09 AU AU11466/88A patent/AU603421B2/en not_active Ceased
- 1988-02-09 KR KR1019880001172A patent/KR930010583B1/ko not_active Expired - Fee Related
- 1988-02-09 DK DK067288A patent/DK67288A/da not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| AU603421B2 (en) | 1990-11-15 |
| KR880009657A (ko) | 1988-10-04 |
| EP0278449A2 (de) | 1988-08-17 |
| US4822789A (en) | 1989-04-18 |
| IL85257A0 (en) | 1988-07-31 |
| DE3874900T2 (de) | 1993-04-01 |
| DK67288D0 (da) | 1988-02-09 |
| KR930010583B1 (ko) | 1993-10-30 |
| EP0278449B1 (de) | 1992-09-30 |
| EP0278449A3 (en) | 1990-05-23 |
| DE3874900D1 (de) | 1992-11-05 |
| CA1300024C (en) | 1992-05-05 |
| AU1146688A (en) | 1988-08-11 |
| ATE81007T1 (de) | 1992-10-15 |
| PH24727A (en) | 1990-10-01 |
| DK67288A (da) | 1988-08-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RH | Patent void |