IL82264A - Water soluble polyvinyl lactam-drug complexes - Google Patents
Water soluble polyvinyl lactam-drug complexesInfo
- Publication number
- IL82264A IL82264A IL82264A IL8226487A IL82264A IL 82264 A IL82264 A IL 82264A IL 82264 A IL82264 A IL 82264A IL 8226487 A IL8226487 A IL 8226487A IL 82264 A IL82264 A IL 82264A
- Authority
- IL
- Israel
- Prior art keywords
- water soluble
- soluble polyvinyl
- drug complexes
- polyvinyl lactam
- lactam
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/12—Oxygen or sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/58—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F8/00—Chemical modification by after-treatment
- C08F8/44—Preparation of metal salts or ammonium salts
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Polymers & Plastics (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US85897686A | 1986-05-02 | 1986-05-02 | |
US06/858,978 US4684698A (en) | 1986-05-02 | 1986-05-02 | Water soluble multicomplex of chlorothiazide, furosemide and poly(N-vinyl-2-pyrrolidone) |
US06/858,778 US4758674A (en) | 1986-05-02 | 1986-05-02 | Water soluble multicomplex of a poly(N-vinyl-2-pyrrolidone)-halogen complex and aminobenzoic acid |
US06/858,635 US4713238A (en) | 1986-05-02 | 1986-05-02 | Water soluble complex of a poly (vinyl lactam) and chlorothiazide and process for producing same |
Publications (2)
Publication Number | Publication Date |
---|---|
IL82264A0 IL82264A0 (en) | 1987-10-30 |
IL82264A true IL82264A (en) | 1991-04-15 |
Family
ID=27505932
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL82264A IL82264A (en) | 1986-05-02 | 1987-04-21 | Water soluble polyvinyl lactam-drug complexes |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP0305384A4 (en) |
JP (1) | JPH01502816A (en) |
AU (1) | AU603796B2 (en) |
CA (1) | CA1281651C (en) |
IL (1) | IL82264A (en) |
WO (1) | WO1987006464A1 (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4900775A (en) * | 1988-02-29 | 1990-02-13 | Gaf Chemicals Corporation | Solubilization of complexes of water-insoluble organic compounds by aqueous solutions of polyvinylpyrrolidone |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BR6681662D0 (en) * | 1965-11-12 | 1973-10-25 | S Santorelli | THERAPEUTIC COMPOSITIONS AND PROCESS TO PREPARE THEM |
US3957972A (en) * | 1966-05-31 | 1976-05-18 | Koninklijke Nederlandsche Gist-En Spiritusfabriek N.V. | Stable solutions of oxytetracycline suitable for parenteral and peroral administration and process of preparation |
US4128632A (en) * | 1978-02-13 | 1978-12-05 | Merck & Co., Inc. | Solubilization of Rafoxanide |
US4344934A (en) * | 1978-11-20 | 1982-08-17 | American Home Products Corporation | Therapeutic compositions with enhanced bioavailability |
US4213963A (en) * | 1978-12-14 | 1980-07-22 | Janssen Pharmaceutica N.V. | Fluspirilene-containing compositions |
US4291015A (en) * | 1979-08-14 | 1981-09-22 | Key Pharmaceuticals, Inc. | Polymeric diffusion matrix containing a vasodilator |
US4542025A (en) * | 1982-07-29 | 1985-09-17 | The Stolle Research And Development Corporation | Injectable, long-acting microparticle formulation for the delivery of anti-inflammatory agents |
DE3234350A1 (en) * | 1982-09-16 | 1984-03-22 | Roland 3400 Göttingen Hemmann | Process for the preparation of a germicidal and surface-anaesthetic medicinal composition |
US4898729A (en) * | 1983-12-09 | 1990-02-06 | Euroceltique, S.A. | Treatment of hypertension, compounds and compositions for antihypertension and diuresis |
-
1987
- 1987-04-06 JP JP62502395A patent/JPH01502816A/en active Pending
- 1987-04-06 AU AU72808/87A patent/AU603796B2/en not_active Ceased
- 1987-04-06 WO PCT/US1987/000763 patent/WO1987006464A1/en not_active Application Discontinuation
- 1987-04-06 EP EP19870903047 patent/EP0305384A4/en not_active Withdrawn
- 1987-04-09 CA CA000534288A patent/CA1281651C/en not_active Expired - Fee Related
- 1987-04-21 IL IL82264A patent/IL82264A/en unknown
Also Published As
Publication number | Publication date |
---|---|
IL82264A0 (en) | 1987-10-30 |
JPH01502816A (en) | 1989-09-28 |
CA1281651C (en) | 1991-03-19 |
WO1987006464A1 (en) | 1987-11-05 |
AU7280887A (en) | 1987-11-24 |
EP0305384A1 (en) | 1989-03-08 |
AU603796B2 (en) | 1990-11-29 |
EP0305384A4 (en) | 1989-06-13 |
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