IL73061A0 - Process for the preparation of the optical antipodes of tert-leucine - Google Patents

Process for the preparation of the optical antipodes of tert-leucine

Info

Publication number
IL73061A0
IL73061A0 IL73061A IL7306184A IL73061A0 IL 73061 A0 IL73061 A0 IL 73061A0 IL 73061 A IL73061 A IL 73061A IL 7306184 A IL7306184 A IL 7306184A IL 73061 A0 IL73061 A0 IL 73061A0
Authority
IL
Israel
Prior art keywords
leucine
tert
preparation
optical antipodes
acyl
Prior art date
Application number
IL73061A
Other versions
IL73061A (en
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of IL73061A0 publication Critical patent/IL73061A0/en
Publication of IL73061A publication Critical patent/IL73061A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/006—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures
    • C12P41/007—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures by reactions involving acyl derivatives of racemic amines
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

1. A process for the preparation of L-tert.-Leucine from N-acyl-D,L-tert.-Leucine, wherein the racemate is resolved in an aqueous medium with an immobilized acylase and the unreacted N-acyl-D-tert.-Leucine and the liberated carboxylic acid are separated off.
IL73061A 1983-09-27 1984-09-25 Process for the preparation of l-tert-leucine IL73061A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19833334848 DE3334848A1 (en) 1983-09-27 1983-09-27 METHOD FOR PRODUCING THE OPTICAL ANTIPODES OF TERT.-LEUCIN

Publications (2)

Publication Number Publication Date
IL73061A0 true IL73061A0 (en) 1984-12-31
IL73061A IL73061A (en) 1988-02-29

Family

ID=6210137

Family Applications (1)

Application Number Title Priority Date Filing Date
IL73061A IL73061A (en) 1983-09-27 1984-09-25 Process for the preparation of l-tert-leucine

Country Status (9)

Country Link
EP (1) EP0137372B1 (en)
JP (1) JPS60105500A (en)
AT (1) ATE21687T1 (en)
AU (1) AU573261B2 (en)
CA (1) CA1229810A (en)
DE (2) DE3334848A1 (en)
DK (1) DK460884A (en)
IL (1) IL73061A (en)
ZA (1) ZA847561B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE191008T1 (en) * 1986-06-04 2000-04-15 Hoechst Schering Agrevo Gmbh METHOD FOR PRODUCING L-TERTIARY LEUCINE BY TRANSAMINATION
WO2010019469A2 (en) * 2008-08-11 2010-02-18 Dr. Reddy's Laboratories Ltd. Preparation of (s)-2-aminobutyric acid
US20120329107A1 (en) * 2009-12-04 2012-12-27 Mitsubishi Gas Chemical Company, Inc. Method for preparing optically active amino acids and optically active amino acid amides

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT169327B (en) * 1948-07-07 1951-11-10 Interchem Corp Process for the separation of the two optical antipodes of a racemic amino acid
GB1072876A (en) * 1965-07-15 1967-06-21 Tanabe Seiyaku Co Resolution of racemic amino acids
FR2078103A5 (en) * 1970-02-03 1971-11-05 Tanabe Seiyaku Co
GB1369462A (en) * 1971-11-23 1974-10-09 Beecham Group Ltd Enzymic resolution of racemic n-acyl-dl-amino acids
JPS5233194B2 (en) * 1973-04-24 1977-08-26
DE2732301C3 (en) * 1977-07-16 1980-12-11 Roehm Gmbh, 6100 Darmstadt Process for the production of stabilized carrier-bound proteins
DE3334846A1 (en) * 1983-09-27 1985-04-04 Hoechst Ag, 6230 Frankfurt IMMOBILIZED ACYLASE, METHOD FOR THEIR PRODUCTION AND THEIR USE

Also Published As

Publication number Publication date
EP0137372B1 (en) 1986-08-27
JPS60105500A (en) 1985-06-10
EP0137372A1 (en) 1985-04-17
DE3460566D1 (en) 1986-10-02
ZA847561B (en) 1985-05-29
CA1229810A (en) 1987-12-01
DK460884A (en) 1985-03-28
DE3334848A1 (en) 1985-04-04
DK460884D0 (en) 1984-09-26
IL73061A (en) 1988-02-29
AU3355684A (en) 1985-04-04
ATE21687T1 (en) 1986-09-15
AU573261B2 (en) 1988-06-02

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