IL72345A - Peptide amides and aldehydes,their manufacture and pharmaceutical compositions containing them - Google Patents

Peptide amides and aldehydes,their manufacture and pharmaceutical compositions containing them

Info

Publication number
IL72345A
IL72345A IL72345A IL7234584A IL72345A IL 72345 A IL72345 A IL 72345A IL 72345 A IL72345 A IL 72345A IL 7234584 A IL7234584 A IL 7234584A IL 72345 A IL72345 A IL 72345A
Authority
IL
Israel
Prior art keywords
aldehydes
manufacture
pharmaceutical compositions
compositions containing
peptide amides
Prior art date
Application number
IL72345A
Other languages
English (en)
Other versions
IL72345A0 (en
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB838318855A external-priority patent/GB8318855D0/en
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of IL72345A0 publication Critical patent/IL72345A0/xx
Publication of IL72345A publication Critical patent/IL72345A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06086Dipeptides with the first amino acid being basic
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0215Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing natural amino acids, forming a peptide bond via their side chain functional group, e.g. epsilon-Lys, gamma-Glu
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08Tripeptides
    • C07K5/0815Tripeptides with the first amino acid being basic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL72345A 1983-07-12 1984-07-09 Peptide amides and aldehydes,their manufacture and pharmaceutical compositions containing them IL72345A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB838318855A GB8318855D0 (en) 1983-07-12 1983-07-12 Peptide derivatives
GB848411635A GB8411635D0 (en) 1983-07-12 1984-05-08 Peptide derivatives

Publications (2)

Publication Number Publication Date
IL72345A0 IL72345A0 (en) 1984-11-30
IL72345A true IL72345A (en) 1988-05-31

Family

ID=26286589

Family Applications (1)

Application Number Title Priority Date Filing Date
IL72345A IL72345A (en) 1983-07-12 1984-07-09 Peptide amides and aldehydes,their manufacture and pharmaceutical compositions containing them

Country Status (11)

Country Link
US (1) US4623639A (da)
EP (1) EP0133225B1 (da)
AU (1) AU578898B2 (da)
CA (1) CA1267499A (da)
DE (1) DE3474670D1 (da)
DK (1) DK304684A (da)
ES (1) ES8601236A1 (da)
IE (1) IE57747B1 (da)
IL (1) IL72345A (da)
NZ (1) NZ208796A (da)
PH (1) PH23381A (da)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3481913D1 (de) * 1983-04-27 1990-05-17 Ici America Inc Prolin-derivate.
DD248961A1 (de) * 1984-05-22 1987-08-26 Akad Wissenschaften Ddr Verfahren zur herstellung wundheilungsfoerdernder praeparationen
HU192646B (en) * 1984-12-21 1987-06-29 Gyogyszerkutato Intezet Process for preparing new n-alkyl-peptide aldehydes
GB8613704D0 (en) * 1986-06-05 1986-07-09 Ici America Inc Difluoro keto compounds
ZA897515B (en) * 1988-10-07 1990-06-27 Merrell Dow Pharma Novel peptidase inhibitors
US5736520A (en) * 1988-10-07 1998-04-07 Merrell Pharmaceuticals Inc. Peptidase inhibitors
WO1990012805A1 (fr) * 1989-04-15 1990-11-01 Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai Postostatine et son compose connexe, ou leurs sels
DK53291D0 (da) * 1991-03-25 1991-03-25 Carlbiotech Ltd As Smaa peptider og peptidrelaterede stoffer samt farmaceutiske praeparater indeholdende saadanne forbindelser
US5714470A (en) 1991-08-22 1998-02-03 Merrell Pharmaceuticals, Inc. Orally-active elastase inhibitors
US5478811A (en) * 1991-08-22 1995-12-26 Merrell Dow Pharmaceuticals Inc. Orally-active elastase inhibitors
IL108031A0 (en) * 1992-12-22 1994-04-12 Procter & Gamble Difluoro pentapeptide derivatives and pharmaceutical compositions containing them
ES2137509T3 (es) * 1994-06-02 1999-12-16 Merrell Pharma Inc Perfluoroalquilcetonas, inhibidoras de elastasa y procedimientos para su preparacion.
DK0762887T3 (da) * 1994-06-02 2002-01-14 Merrell Pharma Inc Acylerede enolderivater som prodrugs for elastase-hæmmere
US5948886A (en) * 1996-11-20 1999-09-07 Hoechst Marion Roussel, Inc. Acylated enol derivatives of α-ketoesters and α-ketoamides
US6172044B1 (en) 1995-12-01 2001-01-09 Aventis Pharmaceuticals Inc. Acylated enol derivative of α-ketoesters and α-ketoamides
US12351780B2 (en) 2019-07-01 2025-07-08 Basf Se Peptide acetals for stabilising enzymes

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3481913D1 (de) * 1983-04-27 1990-05-17 Ici America Inc Prolin-derivate.

Also Published As

Publication number Publication date
EP0133225B1 (de) 1988-10-19
AU3039384A (en) 1985-01-17
AU578898B2 (en) 1988-11-10
DE3474670D1 (en) 1988-11-24
CA1267499A (en) 1990-04-03
IL72345A0 (en) 1984-11-30
DK304684D0 (da) 1984-06-21
US4623639A (en) 1986-11-18
IE57747B1 (en) 1993-03-24
IE841782L (en) 1985-01-12
DK304684A (da) 1985-01-13
EP0133225A2 (de) 1985-02-20
EP0133225A3 (en) 1985-10-02
ES534186A0 (es) 1985-11-01
ES8601236A1 (es) 1985-11-01
NZ208796A (en) 1989-01-27
PH23381A (en) 1989-07-26

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