IL72157A - 6-alpha-hydroxyethyl-2-substituted-2-penem-3-carboxylic acid derivatives and pharmaceutical compositions comprising them - Google Patents
6-alpha-hydroxyethyl-2-substituted-2-penem-3-carboxylic acid derivatives and pharmaceutical compositions comprising themInfo
- Publication number
- IL72157A IL72157A IL72157A IL7215784A IL72157A IL 72157 A IL72157 A IL 72157A IL 72157 A IL72157 A IL 72157A IL 7215784 A IL7215784 A IL 7215784A IL 72157 A IL72157 A IL 72157A
- Authority
- IL
- Israel
- Prior art keywords
- penem
- hydroxyethyl
- alpha
- substituted
- carboxylic acid
- Prior art date
Links
- -1 6-alpha-hydroxyethyl-2-substituted-2-penem-3-carboxylic acid Chemical class 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D499/88—Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C327/00—Thiocarboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/30—Hetero atoms other than halogen
- C07D333/32—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/30—Hetero atoms other than halogen
- C07D333/34—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/46—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings substituted on the ring sulfur atom
- C07D333/48—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings substituted on the ring sulfur atom by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
- C07D335/02—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US50647583A | 1983-06-21 | 1983-06-21 | |
| US61091684A | 1984-05-18 | 1984-05-18 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL72157A0 IL72157A0 (en) | 1984-10-31 |
| IL72157A true IL72157A (en) | 1988-04-29 |
Family
ID=27055489
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL72157A IL72157A (en) | 1983-06-21 | 1984-06-19 | 6-alpha-hydroxyethyl-2-substituted-2-penem-3-carboxylic acid derivatives and pharmaceutical compositions comprising them |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP0130025B1 (xx) |
| AU (1) | AU548624B2 (xx) |
| CA (1) | CA1246546A (xx) |
| DE (1) | DE3464610D1 (xx) |
| DK (1) | DK168440B1 (xx) |
| GR (1) | GR82131B (xx) |
| IE (1) | IE57576B1 (xx) |
| IL (1) | IL72157A (xx) |
| NZ (1) | NZ208595A (xx) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK141784A (da) * | 1983-03-14 | 1984-09-15 | Schering Corp | Penemforbindelser, fremgangsmaader til deres fremstilling samt farmaceutiske praeparater indeholdende disse |
| US4772597A (en) * | 1983-10-14 | 1988-09-20 | Pfizer Inc. | 2-azacycloalkylthiopenem derivatives |
| CH668071A5 (de) * | 1985-05-21 | 1988-11-30 | Lonza Ag | Thiophenonderivate sowie verfahren zur deren herstellung. |
| US4739047A (en) * | 1985-10-17 | 1988-04-19 | Pfizer Inc. | Intermediates for 2-(1-oxo-3-thiolanyl)-2-penem antibiotics |
| ES2029794T3 (es) * | 1985-10-17 | 1992-10-01 | Pfizer Inc. | Procedimiento de preparacion de antibioticos de 2-(1-oxo-3-tiolanil)-2-penem. |
| US4806637A (en) * | 1986-03-17 | 1989-02-21 | Schering Corporation | 6-(Hydroxyethyl)-2-(heterocyclylthio)-penem-3-carboxylates |
| US4695626A (en) * | 1986-07-29 | 1987-09-22 | Pfizer Inc. | 1-aza-4,5-dithiabicyclo [4.2.0] oct-2-en-8-one-2 carboxylate esters |
| DE3775504D1 (en) * | 1986-09-04 | 1992-02-06 | Pfizer | 2-(1-oxo-1-imino-1-thiacycloalkyl)-thiopenem-derivate. |
| WO1988008845A1 (en) * | 1987-05-11 | 1988-11-17 | Pfizer Inc. | Diastereomeric 5r,6s-6-(1r-hydroxyethyl)-2-(cis-1-oxo-3-thiolanylthio)-2-penem-3-carboxylic acids |
| FR2687672B1 (fr) * | 1992-02-20 | 1995-05-12 | Atochem Elf Sa | Nouveaux derives acryliques soufres et leur procede de preparation. |
| US11084833B2 (en) | 2016-10-10 | 2021-08-10 | The Johns Hopkins University | Antibacterial agents against D,D- and L,D-transpeptidases |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4168314A (en) * | 1977-11-17 | 1979-09-18 | Merck & Co., Inc. | 6-(1'-Hydroxyethyl)-2-aminoethylthio-pen-2-em-3-carboxylic acid |
| EP0180252B1 (en) * | 1981-07-15 | 1989-04-26 | Sumitomo Pharmaceuticals Company, Limited | Process of preparing azetidinone compounds |
-
1984
- 1984-06-18 DE DE8484304083T patent/DE3464610D1/de not_active Expired
- 1984-06-18 EP EP84304083A patent/EP0130025B1/en not_active Expired
- 1984-06-19 IL IL72157A patent/IL72157A/xx unknown
- 1984-06-19 CA CA000456950A patent/CA1246546A/en not_active Expired
- 1984-06-20 GR GR75065A patent/GR82131B/el unknown
- 1984-06-20 IE IE1553/84A patent/IE57576B1/en not_active IP Right Cessation
- 1984-06-20 DK DK300984A patent/DK168440B1/da not_active IP Right Cessation
- 1984-06-20 AU AU29534/84A patent/AU548624B2/en not_active Expired
- 1984-06-20 NZ NZ208595A patent/NZ208595A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IE57576B1 (en) | 1992-12-16 |
| IE841553L (en) | 1984-12-21 |
| IL72157A0 (en) | 1984-10-31 |
| DE3464610D1 (de) | 1987-08-13 |
| EP0130025A1 (en) | 1985-01-02 |
| NZ208595A (en) | 1986-11-12 |
| DK168440B1 (da) | 1994-03-28 |
| DK300984A (da) | 1985-02-05 |
| AU2953484A (en) | 1985-01-03 |
| GR82131B (xx) | 1984-12-13 |
| EP0130025B1 (en) | 1987-07-08 |
| DK300984D0 (da) | 1984-06-20 |
| AU548624B2 (en) | 1985-12-19 |
| CA1246546A (en) | 1988-12-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| KB | Patent renewed | ||
| KB | Patent renewed |