IL65423A - Pharmaceutical compositions for the treatment of tumor cell metastasis and growths containing 3-methyl-1-(2-(2-naphthyloxy)-ethyl)-2-pyrazolin-5-one or a pharmaceutically acceptable salt thereof,and their preparation - Google Patents
Pharmaceutical compositions for the treatment of tumor cell metastasis and growths containing 3-methyl-1-(2-(2-naphthyloxy)-ethyl)-2-pyrazolin-5-one or a pharmaceutically acceptable salt thereof,and their preparationInfo
- Publication number
- IL65423A IL65423A IL65423A IL6542382A IL65423A IL 65423 A IL65423 A IL 65423A IL 65423 A IL65423 A IL 65423A IL 6542382 A IL6542382 A IL 6542382A IL 65423 A IL65423 A IL 65423A
- Authority
- IL
- Israel
- Prior art keywords
- pyrazolin
- naphthyloxy
- ethyl
- methyl
- preparation
- Prior art date
Links
- ISBUYSPRIJRBKX-UHFFFAOYSA-N 5-methyl-2-(2-naphthalen-2-yloxyethyl)-4h-pyrazol-3-one Chemical compound O=C1CC(C)=NN1CCOC1=CC=C(C=CC=C2)C2=C1 ISBUYSPRIJRBKX-UHFFFAOYSA-N 0.000 title 1
- 206010027476 Metastases Diseases 0.000 title 1
- 230000012010 growth Effects 0.000 title 1
- 230000009401 metastasis Effects 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 150000003839 salts Chemical class 0.000 title 1
- 210000004881 tumor cell Anatomy 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US25186481A | 1981-04-07 | 1981-04-07 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL65423A0 IL65423A0 (en) | 1982-07-30 |
| IL65423A true IL65423A (en) | 1984-12-31 |
Family
ID=22953719
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL65423A IL65423A (en) | 1981-04-07 | 1982-04-05 | Pharmaceutical compositions for the treatment of tumor cell metastasis and growths containing 3-methyl-1-(2-(2-naphthyloxy)-ethyl)-2-pyrazolin-5-one or a pharmaceutically acceptable salt thereof,and their preparation |
Country Status (17)
| Country | Link |
|---|---|
| EP (1) | EP0062319A1 (it) |
| JP (1) | JPS57179163A (it) |
| AU (1) | AU551063B2 (it) |
| BE (1) | BE892772A (it) |
| CA (1) | CA1265451A (it) |
| CH (1) | CH651753A5 (it) |
| DE (1) | DE3212068A1 (it) |
| ES (3) | ES511209A0 (it) |
| FR (1) | FR2502954B1 (it) |
| GB (1) | GB2095997B (it) |
| GR (1) | GR75460B (it) |
| IL (1) | IL65423A (it) |
| IT (1) | IT1150790B (it) |
| NL (1) | NL8201321A (it) |
| NZ (1) | NZ200234A (it) |
| PH (1) | PH18651A (it) |
| ZA (1) | ZA822335B (it) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040180891A1 (en) * | 2001-09-25 | 2004-09-16 | Uday Khire | Pyrazole derivatives useful in the treatment of hyper-proliferative disorders |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2427272C3 (de) * | 1974-06-06 | 1981-10-01 | Bayer Ag, 5090 Leverkusen | 1-(2-(β-Naphthyloxy)-äthyl)-3-methyl -pyrazolon-(5), Verfahren sowie Verwendung als Antithrombotikum |
-
1982
- 1982-03-30 NL NL8201321A patent/NL8201321A/nl not_active Application Discontinuation
- 1982-03-31 CA CA000400261A patent/CA1265451A/en not_active Expired - Lifetime
- 1982-04-01 DE DE19823212068 patent/DE3212068A1/de not_active Withdrawn
- 1982-04-02 GB GB8209782A patent/GB2095997B/en not_active Expired
- 1982-04-02 EP EP82102800A patent/EP0062319A1/de not_active Withdrawn
- 1982-04-05 NZ NZ200234A patent/NZ200234A/en unknown
- 1982-04-05 AU AU82353/82A patent/AU551063B2/en not_active Ceased
- 1982-04-05 JP JP57055557A patent/JPS57179163A/ja active Pending
- 1982-04-05 GR GR67819A patent/GR75460B/el unknown
- 1982-04-05 IL IL65423A patent/IL65423A/xx unknown
- 1982-04-05 CH CH2133/82A patent/CH651753A5/de not_active IP Right Cessation
- 1982-04-05 ZA ZA822335A patent/ZA822335B/xx unknown
- 1982-04-06 PH PH27109A patent/PH18651A/en unknown
- 1982-04-06 BE BE0/207764A patent/BE892772A/fr not_active IP Right Cessation
- 1982-04-06 ES ES511209A patent/ES511209A0/es active Granted
- 1982-04-06 IT IT20621/82A patent/IT1150790B/it active
- 1982-04-06 FR FR8205947A patent/FR2502954B1/fr not_active Expired
-
1983
- 1983-04-14 ES ES521456A patent/ES8404994A1/es not_active Expired
- 1983-04-14 ES ES521457A patent/ES521457A0/es active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| GB2095997B (en) | 1986-01-22 |
| GB2095997A (en) | 1982-10-13 |
| ES521456A0 (es) | 1984-05-16 |
| NZ200234A (en) | 1985-07-12 |
| CA1265451A (en) | 1990-02-06 |
| GR75460B (it) | 1984-07-20 |
| EP0062319A1 (de) | 1982-10-13 |
| FR2502954A1 (fr) | 1982-10-08 |
| ES8404994A1 (es) | 1984-05-16 |
| ES8404995A1 (es) | 1984-05-16 |
| IL65423A0 (en) | 1982-07-30 |
| JPS57179163A (en) | 1982-11-04 |
| AU551063B2 (en) | 1986-04-17 |
| AU8235382A (en) | 1982-10-14 |
| ES521457A0 (es) | 1984-05-16 |
| IT8220621A0 (it) | 1982-04-06 |
| DE3212068A1 (de) | 1982-11-18 |
| FR2502954B1 (fr) | 1985-10-25 |
| NL8201321A (nl) | 1982-11-01 |
| PH18651A (en) | 1985-08-23 |
| ES8307753A1 (es) | 1983-08-01 |
| ES511209A0 (es) | 1983-08-01 |
| ZA822335B (en) | 1983-03-30 |
| IT1150790B (it) | 1986-12-17 |
| IT8220621A1 (it) | 1983-10-06 |
| CH651753A5 (de) | 1985-10-15 |
| BE892772A (fr) | 1982-10-06 |
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