IL60330A - 7-heteroaryl pyrazolo(1,5-a)pyrimidines - Google Patents

7-heteroaryl pyrazolo(1,5-a)pyrimidines

Info

Publication number
IL60330A
IL60330A IL60330A IL6033080A IL60330A IL 60330 A IL60330 A IL 60330A IL 60330 A IL60330 A IL 60330A IL 6033080 A IL6033080 A IL 6033080A IL 60330 A IL60330 A IL 60330A
Authority
IL
Israel
Prior art keywords
pyrazolo
pyrimidines
heteroaryl
heteroaryl pyrazolo
Prior art date
Application number
IL60330A
Other languages
English (en)
Other versions
IL60330A0 (en
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of IL60330A0 publication Critical patent/IL60330A0/xx
Publication of IL60330A publication Critical patent/IL60330A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
    • C07D213/46—Oxygen atoms
    • C07D213/50—Ketonic radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/22—Radicals substituted by doubly bound hetero atoms, or by two hetero atoms other than halogen singly bound to the same carbon atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL60330A 1979-07-09 1980-06-17 7-heteroaryl pyrazolo(1,5-a)pyrimidines IL60330A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US5594179A 1979-07-09 1979-07-09
US06/124,686 US4281000A (en) 1979-07-09 1980-02-26 Substituted pyrazolo (1,5-a)pyrimidines and their use as anxiolytic agents

Publications (2)

Publication Number Publication Date
IL60330A0 IL60330A0 (en) 1980-09-16
IL60330A true IL60330A (en) 1984-05-31

Family

ID=26734791

Family Applications (1)

Application Number Title Priority Date Filing Date
IL60330A IL60330A (en) 1979-07-09 1980-06-17 7-heteroaryl pyrazolo(1,5-a)pyrimidines

Country Status (12)

Country Link
US (1) US4281000A (de)
EP (1) EP0025819B1 (de)
AR (1) AR227766A1 (de)
AU (1) AU536081B2 (de)
CA (1) CA1140125A (de)
DD (1) DD153840A5 (de)
DE (1) DE3065270D1 (de)
GR (1) GR70075B (de)
HU (1) HU182153B (de)
IL (1) IL60330A (de)
PL (1) PL126652B1 (de)
YU (1) YU172280A (de)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11167081B2 (en) 2016-06-16 2021-11-09 Smiths Medical Asd, Inc. Assemblies and methods for infusion pump system administration sets

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU557300B2 (en) * 1982-03-16 1986-12-18 Farmitalia Carlo Erba S.P.A. Substituted 1h-pyrazolo(1,5-alpha)pyrimidines and processes for their preparation
ZA831407B (en) * 1982-03-25 1983-11-30 Erba Farmitalia Substituted ethenyl derivatives of 1h-pyrazolo(1,5-a)pyrimidine and process for their preparation
US4444774A (en) * 1982-07-29 1984-04-24 American Cyanamid Company 7-Heteroaryl[1,2,4]triazolo[1,5-a]pyrimidines
NZ208554A (en) * 1983-06-23 1987-06-30 American Cyanamid Co (aryl and heteroaryl)-(7-(aryl and heteroaryl)-pyrazolo (1,5-a) pyrimidin-3-yl)-methanone derivatives and pharmaceutical compositions
NZ208555A (en) * 1983-06-23 1987-06-30 American Cyanamid Co (3-amino-1h-pyrazol-4-yl)-arylmethanone derivatives
US4626538A (en) * 1983-06-23 1986-12-02 American Cyanamid Company [7-(3-disubstituted amino)phenyl]pyrazolo[1,5-a]pyrimidines
US4654347A (en) * 1983-06-23 1987-03-31 American Cyanamid Company Aryl and heteroaryl[[7-(3-disubstituted amino)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]methanones
US4521422A (en) * 1983-06-23 1985-06-04 American Cyanamid Company Aryl and heteroaryl[7-(aryl and heteroaryl)pyrazolo[1,5-a]pyrimidin-3-yl]methanones
US4576943A (en) * 1984-10-09 1986-03-18 American Cyanamid Company Pyrazolo[1,5-a]pyrimidines
GB8610531D0 (en) * 1986-04-30 1986-06-04 Fbc Ltd Herbicides
EP0264773A1 (de) * 1986-10-16 1988-04-27 American Cyanamid Company 4,5-Dihydro- und 4,5,6,7-Tetrahydropyrazolo[1,5-a]pyrimidine
US5013737A (en) * 1988-02-22 1991-05-07 American Cyanamid Company 2,4,8-Trisubstituted-3H,6H-1,4,5A,8A-tetraazaacenaphtylene-3,5-(4H)-diones and 2,4-8-trisubstituted-4,5-dihydro-5-thioxo-3H,6H-1,4,5A,8A-tetrazaacenaphthylen-3-ones
US5059709A (en) * 1990-11-13 1991-10-22 American Cyanamid Company Process for the synthesis of α-[(dialkylamino)substituted-methylene]-β-oxo-(substituted)propanentriles
DE4333705C2 (de) * 1993-10-02 2003-10-30 Guenter Ege Arylmethylsubstituierte Pyrazolo-azine, insbesondere 3-Arylmethylpyrazolo[1,5-a]pyrimidine und Verfahren zur Herstellung von 8-Arylmethyl-pyrazolo[5,1-c][1,2,4]triazinen
US5538977A (en) * 1995-03-17 1996-07-23 American Cyanamid Company 3-Substituted-7-[3-(imidazol-1-yl)phenyl]-pyrazolo[1,5-a]pyrimidines
US5714607A (en) * 1995-12-01 1998-02-03 American Cyanamid Company Process improvement in the synthesis of N- 3-(3-cyano-pyrazolo 1,5-a!pyrimidin-7-yl)phenyl!-N-ethylacetamide
WO2000059908A2 (en) 1999-04-06 2000-10-12 Du Pont Pharmaceuticals Company Pyrazolopyrimidines as crf antagonists
GB0202873D0 (en) * 2002-02-07 2002-03-27 Novartis Ag Organic compounds
TW200719895A (en) * 2005-05-26 2007-06-01 Wyeth Corp Method for the treatment of noise phobia in companion animals
US20100029657A1 (en) * 2008-02-29 2010-02-04 Wyeth Bridged, Bicyclic Heterocyclic or Spiro Bicyclic Heterocyclic Derivatives of Pyrazolo[1, 5-A]Pyrimidines, Methods for Preparation and Uses Thereof
WO2013035102A1 (en) 2011-09-05 2013-03-14 Natco Pharma Limited Processes for the preparation of imatinib base and intermediates thereof
CA3196061A1 (en) 2020-10-23 2022-04-28 Ildong Pharmaceutical Co., Ltd. Cftr modulator compounds, compositions, and uses thereof
CN112745300A (zh) * 2021-01-21 2021-05-04 杭州浙中医药科技有限公司 一种制备n-(5-羧基-2-甲基苯基)-4-(3-吡啶)-2-嘧啶胺的方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3157655A (en) * 1962-05-18 1964-11-17 Shionogi & Co Pyrazolopyrimidine derivative
BE786611A (fr) * 1971-08-16 1973-01-22 Int Chem & Nuclear Corp Nouveaux inhibiteurs de xanthine-oxydase et leur procede de preparatio
US3907799A (en) * 1971-08-16 1975-09-23 Icn Pharmaceuticals Xanthine oxidase inhibitors
BE792533A (fr) * 1971-12-09 1973-06-08 Int Chem & Nuclear Corp Nouvelles pyrazolo (1,5a) pyrimidines et leur procede de preparation
US3925385A (en) * 1972-04-20 1975-12-09 Icn Pharmaceuticals 6-Carbethoxy-3,7-disubstitutedpyrazolo{8 1,5a{9 pyrimidines
US4093617A (en) * 1974-11-12 1978-06-06 Icn Pharmaceuticals, Inc. 3,5,7-Trisubstituted pyrazolo[1,5-a]pyrimidines
US4178449A (en) * 1978-04-17 1979-12-11 American Cyanamid Company Pyrazolo[1,5-a]pyrimidines and imidazo-[1,5-a]pyrimidines

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11167081B2 (en) 2016-06-16 2021-11-09 Smiths Medical Asd, Inc. Assemblies and methods for infusion pump system administration sets

Also Published As

Publication number Publication date
IL60330A0 (en) 1980-09-16
AU5951780A (en) 1981-01-15
DD153840A5 (de) 1982-02-03
YU172280A (en) 1983-02-28
US4281000A (en) 1981-07-28
AU536081B2 (en) 1984-04-19
EP0025819B1 (de) 1983-10-12
GR70075B (de) 1982-07-27
AR227766A1 (es) 1982-12-15
PL126652B1 (en) 1983-08-31
PL225541A1 (de) 1981-10-30
HU182153B (en) 1983-12-28
CA1140125A (en) 1983-01-25
EP0025819A1 (de) 1981-04-01
DE3065270D1 (en) 1983-11-17

Similar Documents

Publication Publication Date Title
IL60330A (en) 7-heteroaryl pyrazolo(1,5-a)pyrimidines
GB2048859B (en) Pyrido(2,3-d)pyrimidines
AU538500B2 (en) Pyrazolo(3,4-b)(1,5) benzodiazepine derivatives
AU536351B2 (en) S-triazolo(4,3-b)pyridazines
GB2050353B (en) Substituted pyrido(1,2-a) pyrimidines
IL69417A0 (en) Imidazo(1,2-a)pyrimidines
AU541307B2 (en) Pyrimido (5,4-d) pyrimidine derivatives
AU539466B2 (en) Tetrahydro-pyrrolo/1,2-a/pyrimidines
IL61535A0 (en) 1-oxo-1h-thiazolo(3,2-a)pyrimidine-2-carboxamides
PH16593A (en) 11-piperazinyl 5h-pyrrolo(1,2-b)(1,2,5)benzotriazepines
AU8531482A (en) Imidazo (1,2-a)pyrimidines
CS340780A2 (en) Zpusob vyroby pyrazolo (1,5 c) chinazolinovych derivatu
GB2138418B (en) Novel s-triazole(1,5-a)pyrimidine derivatives
ZA835684B (en) Imidazo(1,2-a)pyrimidines
ZA803591B (en) Substituted pyrazolo(1,5-a)pyrimidines
GB2040940B (en) V-triazolyl-(4,5 - d) - pyrimidines
GB8306905D0 (en) Substituted 1h-pyrazolo(1,5-a)pyrimidines
ZA831611B (en) Substituted 1h-pyrazolo(1,5-a)pyrimidines and process for their preparation
AU541505B2 (en) Pyrimido(1,2-a)azepines
JPS56167686A (en) Pyrazolo(1,2-a)(1,2,4)benzotriazines
IE801395L (en) SUBSTITUTED PYRAZOLO (1, 5-a) PYRIMIDINES, ANXIOLYTIC AGENTS
AU4624379A (en) Pyrido(1,2-a)pyrimidines
ZA802047B (en) Pyrido(2,3-d)pyrimidines
ZA78384B (en) S-triazolo(1,5-a)pyrimidine containing compositions
GB8303089D0 (en) Substituted 1h-pyrazolo 1,5-a pyrimidines