IL53741A - Process for obtaining penicillium stoloniferum mutants with improved ability to synthesize mycophenolic acid - Google Patents
Process for obtaining penicillium stoloniferum mutants with improved ability to synthesize mycophenolic acidInfo
- Publication number
- IL53741A IL53741A IL53741A IL5374178A IL53741A IL 53741 A IL53741 A IL 53741A IL 53741 A IL53741 A IL 53741A IL 5374178 A IL5374178 A IL 5374178A IL 53741 A IL53741 A IL 53741A
- Authority
- IL
- Israel
- Prior art keywords
- mutants
- synthesize
- obtaining
- mycophenolic acid
- improved ability
- Prior art date
Links
- 241000228145 Penicillium brevicompactum Species 0.000 title 1
- HPNSFSBZBAHARI-UHFFFAOYSA-N micophenolic acid Natural products OC1=C(CC=C(C)CCC(O)=O)C(OC)=C(C)C2=C1C(=O)OC2 HPNSFSBZBAHARI-UHFFFAOYSA-N 0.000 title 1
- HPNSFSBZBAHARI-RUDMXATFSA-N mycophenolic acid Chemical compound OC1=C(C\C=C(/C)CCC(O)=O)C(OC)=C(C)C2=C1C(=O)OC2 HPNSFSBZBAHARI-RUDMXATFSA-N 0.000 title 1
- 229960000951 mycophenolic acid Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/02—Oxygen as only ring hetero atoms
- C12P17/04—Oxygen as only ring hetero atoms containing a five-membered hetero ring, e.g. griseofulvin, vitamin C
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/911—Microorganisms using fungi
- Y10S435/933—Penicillium
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Wood Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US77967077A | 1977-03-21 | 1977-03-21 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL53741A true IL53741A (en) | 1981-02-27 |
Family
ID=25117146
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL53741A IL53741A (en) | 1977-03-21 | 1978-01-03 | Process for obtaining penicillium stoloniferum mutants with improved ability to synthesize mycophenolic acid |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US4115197A (fr) |
| JP (1) | JPS53115880A (fr) |
| BE (1) | BE862618A (fr) |
| DD (1) | DD141036A5 (fr) |
| DE (1) | DE2800071A1 (fr) |
| ES (1) | ES465821A1 (fr) |
| FR (1) | FR2384846A1 (fr) |
| GB (1) | GB1593208A (fr) |
| IL (1) | IL53741A (fr) |
| NL (1) | NL7800064A (fr) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5668398A (en) * | 1979-11-07 | 1981-06-09 | Nippon Oil Co Ltd | Prduction of uroporphyrin 3 |
| JPS5678595A (en) * | 1979-11-29 | 1981-06-27 | Nippon Oil Co Ltd | Preparation of coproporphyrin 3 |
| US4452891A (en) * | 1980-09-08 | 1984-06-05 | Ajinomoto Company Incorporated | Method for production of mycophenolic acid by fermentation |
| US7083642B2 (en) * | 2000-12-22 | 2006-08-01 | Avantec Vascular Corporation | Delivery of therapeutic capable agents |
| US6471980B2 (en) | 2000-12-22 | 2002-10-29 | Avantec Vascular Corporation | Intravascular delivery of mycophenolic acid |
| US20030050692A1 (en) * | 2000-12-22 | 2003-03-13 | Avantec Vascular Corporation | Delivery of therapeutic capable agents |
| US7077859B2 (en) | 2000-12-22 | 2006-07-18 | Avantec Vascular Corporation | Apparatus and methods for variably controlled substance delivery from implanted prostheses |
| US20050203612A1 (en) * | 2000-12-22 | 2005-09-15 | Avantec Vascular Corporation | Devices delivering therapeutic agents and methods regarding the same |
| EP1416884A4 (fr) * | 2001-07-26 | 2007-03-07 | Avantec Vascular Corp | Administration d'agents potentiellement therapeutiques |
| WO2003106690A1 (fr) * | 2002-06-18 | 2003-12-24 | Biocon India Limited | Fermentation a l'etat solide a ecoulement discontinu pour la production d'acide mycophenolique |
| WO2005051229A2 (fr) * | 2003-11-24 | 2005-06-09 | Avantec Vascular Corporation | Dispositifs et procedes d'administration d'agents therapeutiques |
| US7683188B2 (en) * | 2004-04-26 | 2010-03-23 | TEVA Gyógyszergyár Zártkōrūen Mūkōdō Részvénytársaság | Process for preparation of mycophenolic acid and ester derivatives thereof |
| CA2583310A1 (fr) * | 2004-10-05 | 2006-04-13 | Biocon Limited | Processus de production d'acide mycophenolique au moyen de la souche bicc7673 de penicillium arenicola |
| EP2032712B1 (fr) * | 2006-06-29 | 2010-02-10 | Ivax Pharmaceuticals S.R.O. | Régulation de la production de métabolites acides |
| WO2008127663A1 (fr) * | 2007-04-11 | 2008-10-23 | Teva Gyógyszergyár Zártköruen Muködo Részvénytársaság | Procédé de réduction du niveau d'impuretés dans une fermentation d'acide mycophénolique |
| US20230218644A1 (en) | 2020-04-16 | 2023-07-13 | Som Innovation Biotech, S.A. | Compounds for use in the treatment of viral infections by respiratory syndrome-related coronavirus |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1642699C3 (de) * | 1966-09-27 | 1978-08-17 | Imperial Chemical Industries Ltd., London | Verfahren zur Herstellung von Mykophenolsäure |
-
1977
- 1977-08-29 US US05/828,392 patent/US4115197A/en not_active Expired - Lifetime
-
1978
- 1978-01-02 DE DE19782800071 patent/DE2800071A1/de not_active Ceased
- 1978-01-03 IL IL53741A patent/IL53741A/xx unknown
- 1978-01-03 NL NL7800064A patent/NL7800064A/xx not_active Application Discontinuation
- 1978-01-04 GB GB122/78A patent/GB1593208A/en not_active Expired
- 1978-01-04 BE BE1008623A patent/BE862618A/fr unknown
- 1978-01-04 FR FR7800142A patent/FR2384846A1/fr active Granted
- 1978-01-05 DD DD78203108A patent/DD141036A5/de unknown
- 1978-01-05 ES ES465821A patent/ES465821A1/es not_active Expired
- 1978-01-05 JP JP35478A patent/JPS53115880A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JPS53115880A (en) | 1978-10-09 |
| DE2800071A1 (de) | 1978-10-05 |
| BE862618A (fr) | 1978-07-04 |
| ES465821A1 (es) | 1978-09-16 |
| NL7800064A (nl) | 1978-09-25 |
| FR2384846A1 (fr) | 1978-10-20 |
| GB1593208A (en) | 1981-07-15 |
| FR2384846B1 (fr) | 1980-10-17 |
| DD141036A5 (de) | 1980-04-09 |
| US4115197A (en) | 1978-09-19 |
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