IL40790A - 3alpha-hydroxy-19-nor-5alpha-pregnane-11,20-dione,its preparation and anaesthetic compositions containing it - Google Patents

3alpha-hydroxy-19-nor-5alpha-pregnane-11,20-dione,its preparation and anaesthetic compositions containing it

Info

Publication number
IL40790A
IL40790A IL40790A IL4079072A IL40790A IL 40790 A IL40790 A IL 40790A IL 40790 A IL40790 A IL 40790A IL 4079072 A IL4079072 A IL 4079072A IL 40790 A IL40790 A IL 40790A
Authority
IL
Israel
Prior art keywords
3alpha
5alpha
pregnane
dione
hydroxy
Prior art date
Application number
IL40790A
Other languages
English (en)
Other versions
IL40790A0 (en
Original Assignee
Glaxo Lab Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Lab Ltd filed Critical Glaxo Lab Ltd
Publication of IL40790A0 publication Critical patent/IL40790A0/xx
Publication of IL40790A publication Critical patent/IL40790A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0007—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa
    • C07J5/0015—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa not substituted in position 16
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J75/00—Processes for the preparation of steroids in general
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
    • C07J7/001—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group
    • C07J7/0015—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group not substituted in position 17 alfa
    • C07J7/002—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group not substituted in position 17 alfa not substituted in position 16

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
IL40790A 1971-11-11 1972-11-10 3alpha-hydroxy-19-nor-5alpha-pregnane-11,20-dione,its preparation and anaesthetic compositions containing it IL40790A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB5246671A GB1409240A (en) 1971-11-11 1971-11-11 Anaesthetic steroid of the 5alpha-pregnane series

Publications (2)

Publication Number Publication Date
IL40790A0 IL40790A0 (en) 1973-01-30
IL40790A true IL40790A (en) 1975-05-22

Family

ID=10464023

Family Applications (1)

Application Number Title Priority Date Filing Date
IL40790A IL40790A (en) 1971-11-11 1972-11-10 3alpha-hydroxy-19-nor-5alpha-pregnane-11,20-dione,its preparation and anaesthetic compositions containing it

Country Status (16)

Country Link
US (1) US3822297A (ja)
JP (1) JPS4861465A (ja)
AU (1) AU476623B2 (ja)
BE (1) BE791196A (ja)
CA (1) CA992068A (ja)
DE (1) DE2255153A1 (ja)
DK (1) DK131296B (ja)
ES (1) ES408509A1 (ja)
FR (1) FR2159447B1 (ja)
GB (1) GB1409240A (ja)
IE (1) IE37076B1 (ja)
IL (1) IL40790A (ja)
NL (1) NL7215225A (ja)
PH (1) PH9928A (ja)
SE (1) SE390025B (ja)
ZA (1) ZA727971B (ja)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3952031A (en) * 1970-11-12 1976-04-20 Glaxo Laboratories Limited Anaesthetic composition containing a steroid of the 5α-pregnane series and method of using same
DE2438020A1 (de) * 1974-08-05 1976-02-26 Schering Ag 18-methyl-19-nor-20-keto-pregnane und verfahren zu ihrer herstellung
US5232917A (en) * 1987-08-25 1993-08-03 University Of Southern California Methods, compositions, and compounds for allosteric modulation of the GABA receptor by members of the androstane and pregnane series
AUPN498095A0 (en) * 1995-08-23 1995-09-14 Goodchild, Colin Stanley Compounds and compositions
US6787530B1 (en) 1996-08-23 2004-09-07 Monash University Use of pregnane-diones as analgesic agents

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1281205A (fr) * 1956-12-21 1962-01-12 Organon Nv Procédé d'obtention de composés de la série du prégnane

Also Published As

Publication number Publication date
FR2159447B1 (ja) 1976-08-20
DE2255153A1 (de) 1973-05-24
AU4875472A (en) 1974-05-16
FR2159447A1 (ja) 1973-06-22
US3822297A (en) 1974-07-02
IL40790A0 (en) 1973-01-30
DK131296C (ja) 1975-11-17
PH9928A (en) 1976-06-14
GB1409240A (en) 1975-10-08
DK131296B (da) 1975-06-23
IE37076B1 (en) 1977-04-27
AU476623B2 (en) 1976-09-30
ZA727971B (en) 1973-09-26
ES408509A1 (es) 1976-05-01
SE390025B (sv) 1976-11-29
IE37076L (en) 1973-05-11
CA992068A (en) 1976-06-29
BE791196A (fr) 1973-05-10
JPS4861465A (ja) 1973-08-28
NL7215225A (ja) 1973-05-15

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