IL37467A - Derivatives of benzopyran-2-carboxylic acid,their preparation and pharmaceutical compositions containing them - Google Patents

Derivatives of benzopyran-2-carboxylic acid,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL37467A
IL37467A IL37467A IL3746771A IL37467A IL 37467 A IL37467 A IL 37467A IL 37467 A IL37467 A IL 37467A IL 3746771 A IL3746771 A IL 3746771A IL 37467 A IL37467 A IL 37467A
Authority
IL
Israel
Prior art keywords
compound
group
formula
carbon atoms
process according
Prior art date
Application number
IL37467A
Other languages
English (en)
Other versions
IL37467A0 (en
Original Assignee
Fisons Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fisons Ltd filed Critical Fisons Ltd
Publication of IL37467A0 publication Critical patent/IL37467A0/xx
Publication of IL37467A publication Critical patent/IL37467A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C07D311/24Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/70Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
    • C07C45/71Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form being hydroxy groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40Unsaturated compounds
    • C07C59/58Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • C07C59/66Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
    • C07C59/68Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/04Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D307/10Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/12Radicals substituted by oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Automatic Assembly (AREA)
IL37467A 1970-08-25 1971-08-06 Derivatives of benzopyran-2-carboxylic acid,their preparation and pharmaceutical compositions containing them IL37467A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB4077770 1970-08-25
GB4398470 1970-09-15
GB5886070 1970-12-11
GB1880771*[A GB1368243A (en) 1970-08-25 1971-06-03 Monochromone-2-carboxylic acids

Publications (2)

Publication Number Publication Date
IL37467A0 IL37467A0 (en) 1971-11-29
IL37467A true IL37467A (en) 1976-08-31

Family

ID=27448435

Family Applications (3)

Application Number Title Priority Date Filing Date
IL47937A IL47937A (en) 1970-08-25 1971-08-06 Pharmaceutical compositions containing 6,8-diethyl-5-hydroxy-4-oxo-4h-1-benzopyran-2-carboxylic acid or a salt thereof
IL37467A IL37467A (en) 1970-08-25 1971-08-06 Derivatives of benzopyran-2-carboxylic acid,their preparation and pharmaceutical compositions containing them
IL47937A IL47937A0 (en) 1970-08-25 1975-08-18 Pharmaceutical compositions containing 6,8-diethyl-5-hydroxy-4-oxo-4h-1-benzopyran-2-carboxylic acid or a salt thereof

Family Applications Before (1)

Application Number Title Priority Date Filing Date
IL47937A IL47937A (en) 1970-08-25 1971-08-06 Pharmaceutical compositions containing 6,8-diethyl-5-hydroxy-4-oxo-4h-1-benzopyran-2-carboxylic acid or a salt thereof

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL47937A IL47937A0 (en) 1970-08-25 1975-08-18 Pharmaceutical compositions containing 6,8-diethyl-5-hydroxy-4-oxo-4h-1-benzopyran-2-carboxylic acid or a salt thereof

Country Status (24)

Country Link
US (1) US3786071A (es)
AR (1) AR192582A1 (es)
AT (3) AT324329B (es)
AU (2) AU469554B2 (es)
BE (1) BE771544A (es)
BG (2) BG19148A3 (es)
CA (1) CA995229A (es)
CH (11) CH579560A5 (es)
DE (1) DE2142526A1 (es)
DK (1) DK129162B (es)
EG (1) EG10680A (es)
FR (1) FR2103489B1 (es)
GB (1) GB1368243A (es)
HU (1) HU165686B (es)
IE (1) IE35506B1 (es)
IL (3) IL47937A (es)
LU (1) LU63765A1 (es)
NL (1) NL7111672A (es)
NO (1) NO134838C (es)
OA (1) OA03909A (es)
PH (1) PH10336A (es)
RO (1) RO62393A (es)
SE (1) SE382457B (es)
YU (3) YU35250B (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1428186A (en) * 1972-06-21 1976-03-17 Fujisawa Pharmaceutical Co Chromone derivatives
US3936563A (en) * 1973-04-18 1976-02-03 Warner-Lambert Company Hydroxymethylene-substituted chromone-3-carboxaldehydes, process for their preparation and intermediates produced thereby
US3928599A (en) * 1973-10-23 1975-12-23 Thomas James Sullivan Method for treating rheumatoid arthritis
US3987185A (en) * 1973-11-12 1976-10-19 Richardson-Merrell Inc. Method of treatment using 1-oxo-1h-2-benzopyran-3-carboxylic acid derivatives
US4148900A (en) * 1973-12-27 1979-04-10 Carlo Erba S.P.A. 5:6-Benzo-γ-pyrone derivatives and process for their preparation
US4065467A (en) * 1973-12-27 1977-12-27 Carlo Erba, S. P. A. 5:6-Benzo δ-pyrone derivatives and process for their preparation
US4115567A (en) * 1973-12-27 1978-09-19 Carlo Erba S. P. A. 6-Carboxy-2-(2'-pyrazinyl)-chromones and esters thereof
ZA753951B (en) * 1974-07-04 1976-06-30 Fisons Ltd A method for the treatment of hyperuricaemia or gout
GB1488707A (en) * 1974-07-10 1977-10-12 Fisons Ltd 5-(2-hydroxy-propoxy)-4-oxo-8-propyl-4h-1-benzopyran-2-carboxylic acid and derivatives thereof
US4033845A (en) * 1975-11-20 1977-07-05 Warner-Lambert Company [2-(4-Oxo-4H-1-benzopyran-2-yl)ethenyl]benzonitriles and benzoic acids
FR2453170A1 (fr) * 1979-04-06 1980-10-31 Clin Midy Acides 5-(2-hydroxy-3-thiopropoxy)chromone-2-carboxyliques et leurs applications comme medicaments presentant notamment des proprietes antianaphylactiques et antiallergiques
WO2019054386A1 (ja) * 2017-09-12 2019-03-21 学校法人工学院大学 複素環化合物又はその塩、gpr35作動薬及び医薬組成物

Also Published As

Publication number Publication date
FR2103489B1 (es) 1974-11-15
AT318612B (de) 1974-11-11
DK129162C (es) 1975-01-27
IE35506L (en) 1972-02-25
LU63765A1 (es) 1972-04-04
AT324329B (de) 1975-08-25
CH573423A5 (es) 1976-03-15
NO134838C (es) 1976-12-21
DK129162B (da) 1974-09-02
IE35506B1 (en) 1976-03-03
OA03909A (fr) 1975-08-14
CH573422A5 (es) 1976-03-15
FR2103489A1 (es) 1972-04-14
IL47937A (en) 1976-08-31
EG10680A (en) 1976-06-30
YU35134B (en) 1980-09-25
CH573421A5 (es) 1976-03-15
CH577495A5 (es) 1976-07-15
BG19148A3 (bg) 1975-04-30
CH577992A5 (es) 1976-07-30
CH577493A5 (es) 1976-07-15
PH10336A (en) 1976-12-09
CH577492A5 (es) 1976-07-15
CA995229A (en) 1976-08-17
HU165686B (es) 1974-10-28
YU35250B (en) 1980-10-31
NL7111672A (es) 1972-02-29
DE2142526A1 (de) 1972-03-02
GB1368243A (en) 1974-09-25
AU3268471A (en) 1973-03-01
IL47937A0 (en) 1975-11-25
NO134838B (es) 1976-09-13
CH595374A5 (es) 1978-02-15
US3786071A (en) 1974-01-15
CH567497A5 (es) 1975-10-15
YU216571A (en) 1980-03-15
YU2179A (en) 1980-04-30
BG18608A3 (bg) 1975-02-25
RO62393A (fr) 1978-08-15
AT323160B (de) 1975-06-25
AU469554B2 (en) 1976-02-19
BE771544A (fr) 1972-02-21
AU8251275A (en) 1975-09-04
IL37467A0 (en) 1971-11-29
CH577494A5 (es) 1976-07-15
CH579560A5 (es) 1976-09-15
AR192582A1 (es) 1973-02-28
SE382457B (sv) 1976-02-02

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