IL327063A - שיטות לטיפול במחלות הקשורות ל-mat2a - Google Patents

שיטות לטיפול במחלות הקשורות ל-mat2a

Info

Publication number
IL327063A
IL327063A IL327063A IL32706326A IL327063A IL 327063 A IL327063 A IL 327063A IL 327063 A IL327063 A IL 327063A IL 32706326 A IL32706326 A IL 32706326A IL 327063 A IL327063 A IL 327063A
Authority
IL
Israel
Prior art keywords
mat2a
treating
methods
related diseases
diseases
Prior art date
Application number
IL327063A
Other languages
English (en)
Original Assignee
Ideaya Biosciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ideaya Biosciences Inc filed Critical Ideaya Biosciences Inc
Publication of IL327063A publication Critical patent/IL327063A/he

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL327063A 2023-09-15 2024-09-13 שיטות לטיפול במחלות הקשורות ל-mat2a IL327063A (he)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US202363583058P 2023-09-15 2023-09-15
US202363605124P 2023-12-01 2023-12-01
US202463665869P 2024-06-28 2024-06-28
PCT/US2024/046774 WO2025059579A1 (en) 2023-09-15 2024-09-13 Methods of treating mat2a related diseases

Publications (1)

Publication Number Publication Date
IL327063A true IL327063A (he) 2026-05-01

Family

ID=93010966

Family Applications (1)

Application Number Title Priority Date Filing Date
IL327063A IL327063A (he) 2023-09-15 2024-09-13 שיטות לטיפול במחלות הקשורות ל-mat2a

Country Status (3)

Country Link
AU (1) AU2024342125A1 (he)
IL (1) IL327063A (he)
WO (1) WO2025059579A1 (he)

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2021006841A (es) 2018-12-10 2021-07-02 Ideaya Biosciences Inc Derivados de 2-oxoquinazolina como inhibidores de metionina adenosiltransferasa 2?.
US11492351B2 (en) 2019-09-12 2022-11-08 Mirati Therapeutics, Inc. MTA-cooperative PRMT5 inhibitors
WO2021086879A1 (en) 2019-10-28 2021-05-06 Tango Therapeutics, Inc. Compounds and methods of use
EP4188920A1 (en) 2020-07-31 2023-06-07 Tango Therapeutics, Inc. Piperidin-1-yl-n-pyrydine-3-yl-2-oxoacetamide derivatives useful for the treatment of mtap-deficient and/or mta-accumulating cancers
KR20240019172A (ko) * 2021-06-02 2024-02-14 아이디어야 바이오사이언시스 인코포레이티드 Mat2a 억제제 및 유형 ii prmt 억제제를 포함하는 병용 요법
JP7406674B2 (ja) 2021-09-13 2023-12-27 アストラゼネカ アクチボラグ スピロ環化合物
WO2023086934A1 (en) * 2021-11-12 2023-05-19 Ideaya Biosciences, Inc. Combination therapy comprising a mat2a inhibitor and a taxane
WO2024118070A1 (en) 2022-11-30 2024-06-06 Ideaya Biosciences, Inc. 2-oxoquinazoline crystalline forms

Also Published As

Publication number Publication date
WO2025059579A1 (en) 2025-03-20
AU2024342125A1 (en) 2026-03-26

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