IL326563A - Crystalline forms of a bet inhibitor - Google Patents

Crystalline forms of a bet inhibitor

Info

Publication number
IL326563A
IL326563A IL326563A IL32656326A IL326563A IL 326563 A IL326563 A IL 326563A IL 326563 A IL326563 A IL 326563A IL 32656326 A IL32656326 A IL 32656326A IL 326563 A IL326563 A IL 326563A
Authority
IL
Israel
Prior art keywords
crystalline forms
bet inhibitor
bet
inhibitor
crystalline
Prior art date
Application number
IL326563A
Other languages
Hebrew (he)
Original Assignee
Nuvation Bio Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nuvation Bio Inc filed Critical Nuvation Bio Inc
Publication of IL326563A publication Critical patent/IL326563A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4436Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
IL326563A 2023-08-25 2024-08-23 Crystalline forms of a bet inhibitor IL326563A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202363578834P 2023-08-25 2023-08-25
PCT/US2024/043727 WO2025049339A2 (en) 2023-08-25 2024-08-23 Crystalline forms of a bet inhibitor

Publications (1)

Publication Number Publication Date
IL326563A true IL326563A (en) 2026-04-01

Family

ID=94820218

Family Applications (1)

Application Number Title Priority Date Filing Date
IL326563A IL326563A (en) 2023-08-25 2024-08-23 Crystalline forms of a bet inhibitor

Country Status (3)

Country Link
AU (1) AU2024329991A1 (en)
IL (1) IL326563A (en)
WO (1) WO2025049339A2 (en)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20150361139A1 (en) * 2013-01-30 2015-12-17 Sandoz Ag Crystalline form of linaclotide
KR20210064310A (en) * 2018-09-22 2021-06-02 토렌트 파마슈티칼스 리미티드 Method for the preparation of pyrazole compounds
EP3997070A4 (en) * 2019-07-02 2023-07-26 Nuvation Bio Inc. Heterocyclic compounds as bet inhibitors
US20220041606A1 (en) * 2020-07-28 2022-02-10 Vanderbilt University Positive allosteric modulators of the muscarinic acetylcholine receptor m1
EP4347615B1 (en) * 2021-06-01 2025-05-21 Synthon B.V. Process for making melflufen or a salt thereof

Also Published As

Publication number Publication date
WO2025049339A3 (en) 2025-05-15
AU2024329991A1 (en) 2026-03-05
WO2025049339A2 (en) 2025-03-06

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