IL326497A - רצף מותאם של גן e2a של וירוס אדנו ליצירת ווקטורים המבוססים על נגזרות adeno-associated viruses - Google Patents
רצף מותאם של גן e2a של וירוס אדנו ליצירת ווקטורים המבוססים על נגזרות adeno-associated virusesInfo
- Publication number
- IL326497A IL326497A IL326497A IL32649726A IL326497A IL 326497 A IL326497 A IL 326497A IL 326497 A IL326497 A IL 326497A IL 32649726 A IL32649726 A IL 32649726A IL 326497 A IL326497 A IL 326497A
- Authority
- IL
- Israel
- Prior art keywords
- aav
- adeno
- adenovirus
- variants
- gene
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/14011—Parvoviridae
- C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
- C12N2750/14141—Use of virus, viral particle or viral elements as a vector
- C12N2750/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/14011—Parvoviridae
- C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
- C12N2750/14151—Methods of production or purification of viral material
- C12N2750/14152—Methods of production or purification of viral material relating to complementing cells and packaging systems for producing virus or viral particles
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2800/00—Nucleic acids vectors
- C12N2800/50—Vectors for producing vectors
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Virology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RU2023121136A RU2023121136A (ru) | 2023-08-11 | Модифицированная последовательность гена Е2а аденовируса для получения векторов на основе аденоассоциированных вирусов (AAV) (варианты) | |
| PCT/RU2024/050178 WO2025038011A1 (en) | 2023-08-11 | 2024-08-02 | Modified sequence of adenovirus e2a gene for producing vectors based on adeno-associated viruses (aav) (variants) |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL326497A true IL326497A (he) | 2026-04-01 |
Family
ID=94632994
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL326497A IL326497A (he) | 2023-08-11 | 2024-08-02 | רצף מותאם של גן e2a של וירוס אדנו ליצירת ווקטורים המבוססים על נגזרות adeno-associated viruses |
Country Status (10)
| Country | Link |
|---|---|
| KR (1) | KR20260052122A (he) |
| CN (1) | CN121816424A (he) |
| AR (1) | AR133525A1 (he) |
| AU (1) | AU2024324024A1 (he) |
| CO (1) | CO2026001527A2 (he) |
| DO (1) | DOP2026000039A (he) |
| IL (1) | IL326497A (he) |
| MX (1) | MX2026001659A (he) |
| TW (1) | TW202506203A (he) |
| WO (1) | WO2025038011A1 (he) |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG11201404741VA (en) * | 2012-02-07 | 2014-09-26 | Global Bio Therapeutics Usa Inc | Compartmentalized method of nucleic acid delivery and compositions and uses thereof |
| KR102535670B1 (ko) * | 2015-06-12 | 2023-05-22 | 글락소스미스클라인 바이오로지칼즈 에스.에이. | 아데노바이러스 폴리뉴클레오티드 및 폴리펩티드 |
| GB201620968D0 (en) * | 2016-12-09 | 2017-01-25 | Glaxosmithkline Biologicals Sa | Adenovirus polynucleotides and polypeptides |
-
2024
- 2024-08-02 IL IL326497A patent/IL326497A/he unknown
- 2024-08-02 KR KR1020267007646A patent/KR20260052122A/ko active Pending
- 2024-08-02 CN CN202480052879.6A patent/CN121816424A/zh active Pending
- 2024-08-02 WO PCT/RU2024/050178 patent/WO2025038011A1/en active Pending
- 2024-08-02 AU AU2024324024A patent/AU2024324024A1/en active Pending
- 2024-08-08 TW TW113129700A patent/TW202506203A/zh unknown
- 2024-08-09 AR ARP240102126A patent/AR133525A1/es unknown
-
2026
- 2026-02-10 MX MX2026001659A patent/MX2026001659A/es unknown
- 2026-02-11 CO CONC2026/0001527A patent/CO2026001527A2/es unknown
- 2026-02-11 DO DO2026000039A patent/DOP2026000039A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DOP2026000039A (es) | 2026-03-15 |
| MX2026001659A (es) | 2026-04-01 |
| AR133525A1 (es) | 2025-10-08 |
| KR20260052122A (ko) | 2026-04-17 |
| WO2025038011A1 (en) | 2025-02-20 |
| CO2026001527A2 (es) | 2026-02-23 |
| TW202506203A (zh) | 2025-02-16 |
| CN121816424A (zh) | 2026-04-07 |
| AU2024324024A1 (en) | 2026-02-26 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL276859A (he) | וקטורים חדשים של וירוס קשור-אדנו (aav), וקטורי aav עם דאמידציה של קפסיד מופחתת ושימושים עבורם | |
| IL286725A (he) | וקטורים אדנו-קשורים מהונדסים לביטוי טרנסגני | |
| Zengel et al. | Structural and cellular biology of adeno-associated virus attachment and entry | |
| WO2019169004A8 (en) | Novel adeno-associated virus (aav) vectors, aav vectors having reduced capsid deamidation and uses therefor | |
| BR112021020054A2 (pt) | Capsídeos de vírus adeno-associado (aav) e composições contendo os mesmos | |
| IL286464A (he) | נגיף של וקטורים הקשורים לעדנו רקומביננטיים | |
| EA201792236A1 (ru) | Получение увеличенных в размере векторов на основе аденоассоциированного вируса | |
| PH12020551938A1 (en) | Liver targeting adeno-associated viral vectors | |
| MY209906A (en) | Lipid nanoparticle formulations of non-viral, capsid-free dna vectors | |
| EP4182467A4 (en) | RECOMBINANT ADENO-ASSOCIATED VIRAL VECTORS FOR MULTILATERAL GENE DELIVERY | |
| ZA202202242B (en) | Isolated modified vp1 capsid protein of aav5 | |
| IL291136A (he) | שיטות ותכשירים לאפנון האינטראקציה בין וירוס קשור אדנו (aav) לבין קולטן aav (aavr) להפצה ביולוגית משתנה של aav | |
| AU2020299026A8 (en) | Methods and AAV vectors for in vivo transduction | |
| CA3301443A1 (en) | Modified sequence of adenovirus e2a gene for producing vectors based on adeno-associated viruses (aav) (variants) | |
| PH12020551319A1 (en) | Viral vectors comprising rdh12 coding regions and methods of treating retinal dystrophies | |
| IL314944A (he) | וירוס קשור אדנו רקומביננטי עם פוליפפטידי קפסיד aav משונים | |
| IL321162A (he) | וקטורי וירוס קשור-אדנו עבור אריזה נכונה של אלמנטים חוזרים | |
| JP2024543001A5 (he) | ||
| AU2021376225A9 (en) | Variant adeno-associated virus (aav)capsid polypeptides and gene therapeutics thereof for treatment of hearing loss | |
| EP4359519A4 (en) | Adeno-associated viral (AAV) vectors for targeted tissue expression of therapeutic genes | |
| EP4370663A4 (en) | Recombinant adeno-associated viral vectors for the treatment of BICTI crystal dystrophy | |
| IL315751A (he) | וקטורים של וירוסים הקשורים לאדנו לנתינה של חומצות גרעין דרך איזורי הרשתית | |
| HK40111053A (en) | Adeno-associated viral (aav) vectors for tissue-targeted expression of therapeutic genes | |
| CA3295663A1 (en) | Host cell protein analysis for adeno-associated virus (aav)-based gene therapy | |
| Dolzhansky et al. | Solitary epithelioid hemangioendothelioma concurrent with nodular parenchymal amyloidosis of the lung and Rosai-Dorfman disease |