IL326205A - Intermediates for synthesizing exatecan mesylate - Google Patents

Intermediates for synthesizing exatecan mesylate

Info

Publication number
IL326205A
IL326205A IL326205A IL32620526A IL326205A IL 326205 A IL326205 A IL 326205A IL 326205 A IL326205 A IL 326205A IL 32620526 A IL32620526 A IL 32620526A IL 326205 A IL326205 A IL 326205A
Authority
IL
Israel
Prior art keywords
intermediates
synthesizing
exatecan mesylate
exatecan
mesylate
Prior art date
Application number
IL326205A
Other languages
Hebrew (he)
Inventor
David Goeddel
James Walker
Austin Wright
Louis Redfern
Original Assignee
Sigma Aldrich Co Llc
David Goeddel
James Walker
Austin Wright
Louis Redfern
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma Aldrich Co Llc, David Goeddel, James Walker, Austin Wright, Louis Redfern filed Critical Sigma Aldrich Co Llc
Publication of IL326205A publication Critical patent/IL326205A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/18Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1896Compounds having one or more Si-O-acyl linkages

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Indole Compounds (AREA)
IL326205A 2023-07-27 2024-07-25 Intermediates for synthesizing exatecan mesylate IL326205A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202363516024P 2023-07-27 2023-07-27
PCT/US2024/039606 WO2025024697A1 (en) 2023-07-27 2024-07-25 Intermediates for synthesizing exatecan mesylate

Publications (1)

Publication Number Publication Date
IL326205A true IL326205A (en) 2026-03-01

Family

ID=92295905

Family Applications (1)

Application Number Title Priority Date Filing Date
IL326205A IL326205A (en) 2023-07-27 2024-07-25 Intermediates for synthesizing exatecan mesylate

Country Status (4)

Country Link
KR (1) KR20260048597A (en)
CN (1) CN121909178A (en)
IL (1) IL326205A (en)
WO (1) WO2025024697A1 (en)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112020003466B1 (en) 2017-08-31 2023-12-12 Daiichi Sankyo Company, Limited COMPOST PRODUCTION METHODS, AND, COMPOST
US12252502B2 (en) * 2019-01-11 2025-03-18 Cj Cheiljedang Corporation L-glufosinate intermediate and L-glufosinate preparation method
CN111470998B (en) 2020-06-28 2020-09-25 上海皓元生物医药科技有限公司 Intermediate for synthesizing camptothecin derivative and preparation method and application thereof
CN115724758B (en) * 2021-08-24 2024-12-27 杭州中美华东制药有限公司 Camptothecin derivative intermediate, synthesis method thereof and method for synthesizing camptothecin derivative by using intermediate
CN118119594A (en) * 2021-10-26 2024-05-31 上海弼领生物技术有限公司 A camptothecin derivative intermediate, preparation method and use thereof

Also Published As

Publication number Publication date
CN121909178A (en) 2026-04-21
WO2025024697A1 (en) 2025-01-30
KR20260048597A (en) 2026-04-10

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