IL326113A - שיטות לשימוש במעכבי פקטור b - Google Patents

שיטות לשימוש במעכבי פקטור b

Info

Publication number
IL326113A
IL326113A IL326113A IL32611326A IL326113A IL 326113 A IL326113 A IL 326113A IL 326113 A IL326113 A IL 326113A IL 32611326 A IL32611326 A IL 32611326A IL 326113 A IL326113 A IL 326113A
Authority
IL
Israel
Prior art keywords
inhibitors
factor
methods
Prior art date
Application number
IL326113A
Other languages
English (en)
Inventor
Jorg Eder
Thomas Holbro
Rajesh Singh Karan
Bernd C Kieseier
Wellensiek Anna Svenja Schubart
Original Assignee
Novartis Ag
Jorg Eder
Thomas Holbro
Rajesh Singh Karan
Bernd C Kieseier
Wellensiek Anna Svenja Schubart
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag, Jorg Eder, Thomas Holbro, Rajesh Singh Karan, Bernd C Kieseier, Wellensiek Anna Svenja Schubart filed Critical Novartis Ag
Publication of IL326113A publication Critical patent/IL326113A/he

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4523Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/436Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52Purines, e.g. adenine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/53751,4-Oxazines, e.g. morpholine
    • A61K31/53771,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/675Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13Cyclosporins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • A61P21/04Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL326113A 2023-08-25 2024-08-23 שיטות לשימוש במעכבי פקטור b IL326113A (he)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202363578694P 2023-08-25 2023-08-25
US202463668430P 2024-07-08 2024-07-08
PCT/IB2024/058205 WO2025046421A1 (en) 2023-08-25 2024-08-23 Methods of using factor b inhibitors

Publications (1)

Publication Number Publication Date
IL326113A true IL326113A (he) 2026-03-01

Family

ID=93061572

Family Applications (1)

Application Number Title Priority Date Filing Date
IL326113A IL326113A (he) 2023-08-25 2024-08-23 שיטות לשימוש במעכבי פקטור b

Country Status (5)

Country Link
CN (1) CN121712505A (he)
AU (1) AU2024332373A1 (he)
IL (1) IL326113A (he)
TW (1) TW202508580A (he)
WO (1) WO2025046421A1 (he)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JO3425B1 (ar) 2013-07-15 2019-10-20 Novartis Ag مشتقات البابيريدينيل-اندول واستخدامها كعامل متمم لمثبطات b
TW202504893A (zh) 2020-05-18 2025-02-01 瑞士商諾華公司 Lnp023之結晶形式
CN114057758A (zh) * 2020-08-07 2022-02-18 上海美悦生物科技发展有限公司 补体因子b抑制剂及其药物组合物、制备方法和用途

Also Published As

Publication number Publication date
CN121712505A (zh) 2026-03-20
AU2024332373A1 (en) 2025-10-23
TW202508580A (zh) 2025-03-01
WO2025046421A1 (en) 2025-03-06

Similar Documents

Publication Publication Date Title
IL325340A (he) מעכבי kras
ZA202212146B (en) Inhibitors of nek7 kinase
IL320739A (he) מעכבי rock2
IL314049A (he) מעכבי parp7
IL287293A (he) מעכבים לעריכת רנא ושיטות לשימוש
EP4452967A4 (en) Inhibitors of sars-cov-2
IL316616A (he) מעכבי rock2
IL316204A (he) שיטות למתן מעכבי מיוזין
IL313548A (he) מעכבי met קינאז
HUE072981T2 (hu) Azakinolinok mint CD38 gátlók
IL312466A (he) מעכבי pi3k-אלפא ושיטות להכנה ולשימוש בהם
LT4192814T (lt) Transgliutaminazės inhibitoriai
IL317768A (he) שיטות להכנת מעכבי btk שהותאמו
IL315980A (he) מעכבי egfr
SI4192813T1 (sl) Zaviralci transglutaminaz
IL326113A (he) שיטות לשימוש במעכבי פקטור b
SI4192812T1 (sl) Zaviralci transglutaminaz
GB202203181D0 (en) Inhibitors of elF4A
CA3294294A1 (en) Methods of using factor b inhibitors
CA3283726A1 (en) Methods of using factor b inhibitors
HK40128702A (en) Methods of using factor b inhibitors
GB202107612D0 (en) Inhibitors of metallo-beta-lactamases
IL320661A (he) צורות מוצקות של מעכבי גורם משלים b
IL320219A (he) מעכבים
CA3289184A1 (en) Heteroarylindole inhibitors of apol-1