IL326074A - הרכבים המכוונים לחלבון הפעלת פיברובלסטים ושיטות לשימוש בהם - Google Patents

הרכבים המכוונים לחלבון הפעלת פיברובלסטים ושיטות לשימוש בהם

Info

Publication number
IL326074A
IL326074A IL326074A IL32607426A IL326074A IL 326074 A IL326074 A IL 326074A IL 326074 A IL326074 A IL 326074A IL 32607426 A IL32607426 A IL 32607426A IL 326074 A IL326074 A IL 326074A
Authority
IL
Israel
Prior art keywords
methods
activation protein
fibroblast activation
targeted compositions
targeted
Prior art date
Application number
IL326074A
Other languages
English (en)
Original Assignee
Ratio Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ratio Therapeutics Inc filed Critical Ratio Therapeutics Inc
Publication of IL326074A publication Critical patent/IL326074A/he

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0497—Organic compounds conjugates with a carrier being an organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A61K49/0032—Methine dyes, e.g. cyanine dyes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/005—Fluorescence in vivo characterised by the carrier molecule carrying the fluorescent agent
    • A61K49/0052—Small organic molecules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/041—Heterocyclic compounds
    • A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K51/0455—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Optics & Photonics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
IL326074A 2023-07-28 2024-07-26 הרכבים המכוונים לחלבון הפעלת פיברובלסטים ושיטות לשימוש בהם IL326074A (he)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202363529522P 2023-07-28 2023-07-28
US202463627309P 2024-01-31 2024-01-31
PCT/US2024/039697 WO2025029608A1 (en) 2023-07-28 2024-07-26 Fibroblast activation protein-targeted compositions and methods of use thereof

Publications (1)

Publication Number Publication Date
IL326074A true IL326074A (he) 2026-03-01

Family

ID=92456707

Family Applications (1)

Application Number Title Priority Date Filing Date
IL326074A IL326074A (he) 2023-07-28 2024-07-26 הרכבים המכוונים לחלבון הפעלת פיברובלסטים ושיטות לשימוש בהם

Country Status (5)

Country Link
KR (1) KR20260049219A (he)
CN (1) CN121909051A (he)
AU (1) AU2024316927A1 (he)
IL (1) IL326074A (he)
WO (1) WO2025029608A1 (he)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2026039503A1 (en) 2024-08-13 2026-02-19 Ratio Therapeutics, Inc. Fibroblast activation protein-targeted compositions and methods of use thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015149922A2 (en) 2014-03-31 2015-10-08 Boehringer Ingelheim Vetmedica Gmbh Inhaler
CN110997063B (zh) 2017-05-30 2022-04-29 反射医疗公司 用于计算放射注量的方法的放射治疗系统
EA202090776A1 (ru) * 2017-10-23 2020-07-27 Дзе Джонс Хопкинс Юниверсити Визуализирующие и радиотерапевтические агенты, нацеленные на фибробласт-активирующий белок-альфа (fapalpha)
US11279698B2 (en) 2018-11-20 2022-03-22 Cornell University Macrocyclic complexes of alpha-emitting radionuclides and their use in targeted radiotherapy of cancer
JP2025526460A (ja) * 2022-07-28 2025-08-13 レイシオ・セラピューティクス，インコーポレーテッド 線維芽細胞活性化タンパク質標的組成物およびその使用の方法

Also Published As

Publication number Publication date
WO2025029608A1 (en) 2025-02-06
AU2024316927A1 (en) 2026-02-26
KR20260049219A (ko) 2026-04-13
CN121909051A (zh) 2026-04-21

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