IL325890A - Modulators of the adenosine a2a and a2b receptor - Google Patents

Modulators of the adenosine a2a and a2b receptor

Info

Publication number
IL325890A
IL325890A IL325890A IL32589026A IL325890A IL 325890 A IL325890 A IL 325890A IL 325890 A IL325890 A IL 325890A IL 32589026 A IL32589026 A IL 32589026A IL 325890 A IL325890 A IL 325890A
Authority
IL
Israel
Prior art keywords
adenosine
modulators
receptor
Prior art date
Application number
IL325890A
Other languages
Hebrew (he)
Original Assignee
Ryvu Therapeutics S A
BioNTech SE
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ryvu Therapeutics S A, BioNTech SE filed Critical Ryvu Therapeutics S A
Publication of IL325890A publication Critical patent/IL325890A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL325890A 2023-07-17 2023-07-17 Modulators of the adenosine a2a and a2b receptor IL325890A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/PL2023/050060 WO2025018901A1 (en) 2023-07-17 2023-07-17 Modulators of the adenosine a2a and a2b receptor

Publications (1)

Publication Number Publication Date
IL325890A true IL325890A (en) 2026-03-01

Family

ID=87696037

Family Applications (1)

Application Number Title Priority Date Filing Date
IL325890A IL325890A (en) 2023-07-17 2023-07-17 Modulators of the adenosine a2a and a2b receptor

Country Status (4)

Country Link
CN (1) CN121532395A (en)
AU (1) AU2023454063A1 (en)
IL (1) IL325890A (en)
WO (1) WO2025018901A1 (en)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001058241A2 (en) 2000-02-10 2001-08-16 New York University Adenosine a2a receptor antagonists for treating and preventing hepatic fibrosis, cirrhosis and fatty liver
JP2005123160A (en) 2003-09-22 2005-05-12 Nissan Motor Co Ltd Fuel cell separator, fuel cell stack, fuel cell separator manufacturing method, and fuel cell vehicle
CN101060841A (en) 2004-06-17 2007-10-24 加利福尼亚大学董事会 Antagonizing an adenosine A2A receptor to amelioriate one or more components of addictive behavior
WO2017098421A1 (en) 2015-12-08 2017-06-15 Glaxosmithkline Intellectual Property Development Limited Benzothiadiazine compounds
US20200369665A1 (en) 2017-06-30 2020-11-26 Ryvu Therapeutics S.A. Imidazo[1,2-a]pyrazine modulators of the adenosine a2a receptor
WO2020128036A1 (en) 2018-12-21 2020-06-25 Ryvu Therapeutics S.A. Modulators of the adenosine a2a receptor

Also Published As

Publication number Publication date
AU2023454063A1 (en) 2026-01-15
WO2025018901A1 (en) 2025-01-23
CN121532395A (en) 2026-02-13

Similar Documents

Publication Publication Date Title
GB2609879B (en) Antagonists of the adenosine A2a receptor
AU2022246176A1 (en) Adenosine deaminase variants and uses thereof
IL276873A (en) Imidazopyrimidines and triazolopyrimidines as a2a / a2b inhibitors
IL270909A (en) Imidazo[1,2-a]pyrazine modulators of the adenosine a2a receptor
IL277160A (en) 4'-halogen containing nucleotide and nucleoside therapeutic compositions and uses related thereto
EP4141007A4 (en) Antiviral application of nucleoside analog or combination formulation containing nucleoside analog
IL279562A (en) Nucleosides and nucleotides with 3ʹ-hydroxy blocking groups
EP4185296A4 (en) Adenosine a2a and a2b receptor dual antagonists for immuno-oncology
ZA200703229B (en) Use of A2A adenosine receptor agonists
HUE066718T2 (en) Pyrazolopyridines and triazolopyridines as a2a / a2b inhibitors
EP4040965A4 (en) 4'-halogen containing nucleotide and nucleoside therapeutic compositions and uses related thereto
GB202217705D0 (en) Multi-seat escape system and ejection seat sequencer
IL311972A (en) Activatable cytokine constructs and combination methods
CA3295477A1 (en) Modulators of the adenosine a2a and a2b receptor
EP4234566A4 (en) Modified nucleoside or nucleotide
EP4192916A4 (en) Combination therapy with adenosine receptor antagonists
IL307967A (en) Purine nucleosides, their intermediates, and methods of preparation thereof
PL3833756T3 (en) Epimerase enzymes and their use
HK40081026A (en) Cd73 inhibitor and a2a/a2b adenosine receptor inhibitor combination therapy
HK40089682A (en) Antagonists of the adenosine a2a receptor
EP4108670A4 (en) Bridged nucleoside and nucleotide using same
HK40065313A (en) Adenosine a2a receptor antagonists and uses thereof
HK40106784A (en) Adenosine deaminase variants and uses thereof
IL287417A (en) Cytidine derivatives and methods of forming cytidine derivatives
HK40045143A (en) Expansion of tumor infiltrating lymphocytes (tils) with adenosine a2a receptor antagonists and therapeutic combinations of tils and adenosine a2a receptor antagonists