IL325832A - Formulations and uses of rock2 inhibitors for als - Google Patents

Formulations and uses of rock2 inhibitors for als

Info

Publication number
IL325832A
IL325832A IL325832A IL32583226A IL325832A IL 325832 A IL325832 A IL 325832A IL 325832 A IL325832 A IL 325832A IL 32583226 A IL32583226 A IL 32583226A IL 325832 A IL325832 A IL 325832A
Authority
IL
Israel
Prior art keywords
als
formulations
rock2 inhibitors
rock2
inhibitors
Prior art date
Application number
IL325832A
Other languages
Hebrew (he)
Original Assignee
Graviton Bioscience Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Graviton Bioscience Bv filed Critical Graviton Bioscience Bv
Publication of IL325832A publication Critical patent/IL325832A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL325832A 2023-07-17 2024-07-17 Formulations and uses of rock2 inhibitors for als IL325832A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202363514039P 2023-07-17 2023-07-17
PCT/IB2024/056935 WO2025017499A1 (en) 2023-07-17 2024-07-17 Formulations and uses of rock2 inhibitors for als

Publications (1)

Publication Number Publication Date
IL325832A true IL325832A (en) 2026-03-01

Family

ID=92302394

Family Applications (1)

Application Number Title Priority Date Filing Date
IL325832A IL325832A (en) 2023-07-17 2024-07-17 Formulations and uses of rock2 inhibitors for als

Country Status (3)

Country Link
AU (1) AU2024292342A1 (en)
IL (1) IL325832A (en)
WO (1) WO2025017499A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2026053168A1 (en) * 2024-09-06 2026-03-12 Graviton Bioscience Bv Amorphous forms of a rock2 inhibitor and formulations thereof

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990005723A1 (en) 1988-11-24 1990-05-31 Yoshitomi Pharmaceutical Industries, Ltd. Trans-4-amino(alkyl)-1-pyridylcarbamoyl-cyclohexane compounds and their medicinal use
DE4201178C2 (en) 1992-01-17 1995-12-07 Alfatec Pharma Gmbh Process for the production of soft gelatin capsules by a dropping process
NL1009107C2 (en) 1997-11-12 1999-06-15 Banner Pharmacaps Inc Extrusion device for forming multi layer gelatine films used to form soft gel capsules - contains two height adjustable gate valves covering nozzle opening to control thickness of the individual extruded gelatine film layers
JP2002529398A (en) 1998-11-11 2002-09-10 バイオプログレス・テクノロジー・インターナショナル・インコーポレイテッド Capsules for drug delivery systems
US6340473B1 (en) 1999-07-07 2002-01-22 R.P. Scherer Technologies, Inc. Film forming compositions comprising modified starches and iota-carrageenan and methods for manufacturing soft capsules using same
ES2387780T3 (en) 2003-10-06 2012-10-01 Glaxosmithkline Llc Preparation of 1,6-disubstituted azabenzimidazoles as kinase inhibitors
US7592357B2 (en) 2004-02-20 2009-09-22 Smithkline Beecham Corporation Compounds
CR9465A (en) 2005-03-25 2008-06-19 Surface Logix Inc PHARMACOCINETICALLY IMPROVED COMPOUNDS
PT1905452E (en) 2005-07-12 2013-07-16 Kowa Co Agent for prevention or treatment of glaucoma
GB0704932D0 (en) 2007-03-14 2007-04-25 Astex Therapeutics Ltd Pharmaceutical compounds
WO2011130740A2 (en) 2010-04-16 2011-10-20 H. Lee Moffitt Cancer Center And Research Institute, Inc. Pyridylthiazole-based ureas as inhibitors of rho associated protein kinase (rock) and methods of use
CN113620933A (en) 2012-10-05 2021-11-09 卡德门企业有限公司 RHO kinase inhibitors
US11311541B2 (en) 2014-04-09 2022-04-26 Kadmon Corporation, Llc Treatment of GVHD
CN110582489B (en) 2017-06-30 2023-10-27 北京泰德制药股份有限公司 Rho-related protein kinase inhibitors, pharmaceutical compositions containing the same and preparation methods and uses thereof
WO2019000682A1 (en) 2017-06-30 2019-01-03 北京泰德制药股份有限公司 Rho-associated protein kinase inhibitor, pharmaceutical composition containing rho-associated protein kinase inhibitor, preparation method and use of the pharmaceutical composition
US10323023B2 (en) 2017-06-30 2019-06-18 Beijing Tide Pharmaceutical Co., Ltd. Rho-associated protein kinase inhibitor, pharmaceutical composition comprising the same, as well as preparation method and use thereof
GB201801226D0 (en) 2018-01-25 2018-03-14 Redx Pharma Plc Modulators of Rho-associated protein kinase
CN112969694B (en) 2018-11-09 2023-06-13 北京泰德制药股份有限公司 Rho-associated protein kinase inhibitors, pharmaceutical compositions containing same and uses thereof
BR112021017354A2 (en) 2019-03-01 2021-11-16 Beijing Tide Pharmaceutical Co Ltd Method for treating fatty liver disease and/or steatohepatitis
CA3144113A1 (en) 2019-06-25 2020-12-30 Beijing Tide Pharmaceutical Co., Ltd. Method for treating idiopathic pulmonary fibrosis
KR20230058466A (en) 2020-08-31 2023-05-03 베이징 타이드 파마슈티컬 코퍼레이션 리미티드 Methods for preparing novel RHO-associated protein kinase inhibitors and intermediates in manufacturing methods
JP2023539276A (en) * 2020-08-31 2023-09-13 ベイジン タイド ファーマシューティカル カンパニー リミテッド Salts of RHO-related protein kinase inhibitors, solid forms thereof, methods of preparation thereof and uses thereof
JP7284355B1 (en) 2021-09-30 2023-05-30 京セラ株式会社 Electrochemical cells, electrochemical cell devices, modules and module housing devices
KR20240095429A (en) * 2021-11-16 2024-06-25 베이징 타이드 파마슈티컬 코퍼레이션 리미티드 Nanocrystal preparation of ROCK2 inhibitor and method for preparing the same
CN120882712A (en) 2022-11-21 2025-10-31 格雷威顿生物科技有限公司 ROCK2 inhibitors

Also Published As

Publication number Publication date
AU2024292342A1 (en) 2026-02-26
WO2025017499A1 (en) 2025-01-23

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