IL325620A - מעכבי קינאז 1 דמויי-polo - Google Patents

מעכבי קינאז 1 דמויי-polo

Info

Publication number
IL325620A
IL325620A IL325620A IL32562025A IL325620A IL 325620 A IL325620 A IL 325620A IL 325620 A IL325620 A IL 325620A IL 32562025 A IL32562025 A IL 32562025A IL 325620 A IL325620 A IL 325620A
Authority
IL
Israel
Prior art keywords
polo
kinase
inhibitors
Prior art date
Application number
IL325620A
Other languages
English (en)
Original Assignee
Resero Therapeutics Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Resero Therapeutics Llc filed Critical Resero Therapeutics Llc
Publication of IL325620A publication Critical patent/IL325620A/he

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72Quinazolines; Hydrogenated quinazolines
    • C07D239/78Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 2
    • C07D239/84Nitrogen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epidemiology (AREA)
IL325620A 2023-07-03 2025-12-25 מעכבי קינאז 1 דמויי-polo IL325620A (he)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202363524795P 2023-07-03 2023-07-03
PCT/US2024/036576 WO2025010279A2 (en) 2023-07-03 2024-07-02 Polo-like kinase 1 inhibitors

Publications (1)

Publication Number Publication Date
IL325620A true IL325620A (he) 2026-02-01

Family

ID=94172200

Family Applications (1)

Application Number Title Priority Date Filing Date
IL325620A IL325620A (he) 2023-07-03 2025-12-25 מעכבי קינאז 1 דמויי-polo

Country Status (4)

Country Link
KR (1) KR20260032604A (he)
AU (1) AU2024290917A1 (he)
IL (1) IL325620A (he)
WO (1) WO2025010279A2 (he)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2651072A1 (en) * 2006-05-01 2007-11-08 Pfizer Products Inc. Substituted 2-amino-fused heterocyclic compounds
WO2009084695A1 (ja) * 2007-12-28 2009-07-09 Carna Biosciences Inc. 2-アミノキナゾリン誘導体
WO2014201173A1 (en) * 2013-06-12 2014-12-18 Amgen Inc. Bicyclic sulfonamide compounds as sodium channel inhibitors
AU2014308616B2 (en) * 2013-08-23 2018-12-06 Neupharma, Inc. Certain chemical entities, compositions, and methods
AU2014331794C1 (en) * 2013-10-10 2019-09-12 Araxes Pharma Llc Inhibitors of KRAS G12C
EP4240363A4 (en) * 2020-11-09 2024-10-23 Merck Sharp & Dohme LLC 2-AMINOQUINAZOLINE 7-PHENYL SUBSTITUTED, HPK1 INHIBITORS

Also Published As

Publication number Publication date
AU2024290917A1 (en) 2026-01-22
WO2025010279A2 (en) 2025-01-09
WO2025010279A3 (en) 2025-05-01
WO2025010279A9 (en) 2025-12-18
KR20260032604A (ko) 2026-03-09

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