IL325580A - Treatment of chronic pain or gastrointestinal disorders using buprenorphine dimer - Google Patents
Treatment of chronic pain or gastrointestinal disorders using buprenorphine dimerInfo
- Publication number
- IL325580A IL325580A IL325580A IL32558025A IL325580A IL 325580 A IL325580 A IL 325580A IL 325580 A IL325580 A IL 325580A IL 32558025 A IL32558025 A IL 32558025A IL 325580 A IL325580 A IL 325580A
- Authority
- IL
- Israel
- Prior art keywords
- treatment
- chronic pain
- gastrointestinal disorders
- buprenorphine dimer
- buprenorphine
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/08—Bridged systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Emergency Medicine (AREA)
- Rheumatology (AREA)
- Dermatology (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202363512783P | 2023-07-10 | 2023-07-10 | |
| US202463568538P | 2024-03-22 | 2024-03-22 | |
| PCT/US2024/037128 WO2025014912A1 (en) | 2023-07-10 | 2024-07-09 | Treatment of chronic pain or gastrointestinal disorders using buprenorphine dimer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL325580A true IL325580A (en) | 2026-02-01 |
Family
ID=94216216
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL325580A IL325580A (en) | 2023-07-10 | 2025-12-23 | Treatment of chronic pain or gastrointestinal disorders using buprenorphine dimer |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP4743466A1 (en) |
| KR (1) | KR20260055394A (en) |
| CN (1) | CN121773116A (en) |
| AU (1) | AU2024288358A1 (en) |
| IL (1) | IL325580A (en) |
| WO (1) | WO2025014912A1 (en) |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HUE036084T2 (en) * | 2014-04-28 | 2018-06-28 | Orphomed Inc | Buprenorphine dimer and its use in the treatment of gastrointestinal disorders |
| TW201725040A (en) * | 2015-10-26 | 2017-07-16 | 奧佛麥德公司 | Use of buprenorphine dimer in the treatment of peripheral neuropathic pain |
| WO2018222921A1 (en) * | 2017-05-31 | 2018-12-06 | Napo Pharmaceuticals, Inc. | Methods and compositions for treating bile acid diarrhea, diarrhea associated with small intestine resection or gallbladder removal, and short bowel syndrome |
| WO2021262763A1 (en) * | 2020-06-23 | 2021-12-30 | Arriba Biopharma, Inc. | Opioid receptor modulator and use thereof |
-
2024
- 2024-07-09 KR KR1020267003887A patent/KR20260055394A/en active Pending
- 2024-07-09 AU AU2024288358A patent/AU2024288358A1/en active Pending
- 2024-07-09 WO PCT/US2024/037128 patent/WO2025014912A1/en not_active Ceased
- 2024-07-09 CN CN202480046528.4A patent/CN121773116A/en active Pending
- 2024-07-09 EP EP24840405.5A patent/EP4743466A1/en active Pending
-
2025
- 2025-12-23 IL IL325580A patent/IL325580A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2025014912A1 (en) | 2025-01-16 |
| EP4743466A1 (en) | 2026-05-20 |
| CN121773116A (en) | 2026-03-31 |
| AU2024288358A1 (en) | 2026-01-22 |
| KR20260055394A (en) | 2026-04-23 |
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