IL325487A - ליפידים הניתנים ליינון - Google Patents

ליפידים הניתנים ליינון

Info

Publication number
IL325487A
IL325487A IL325487A IL32548725A IL325487A IL 325487 A IL325487 A IL 325487A IL 325487 A IL325487 A IL 325487A IL 32548725 A IL32548725 A IL 32548725A IL 325487 A IL325487 A IL 325487A
Authority
IL
Israel
Prior art keywords
ionizable lipids
ionizable
lipids
Prior art date
Application number
IL325487A
Other languages
English (en)
Inventor
Sabah Kasmi
Coen Ruben De
Koker Stefaan De
Shrinivas Dumbre
Original Assignee
Etherna Immunotherapies Nv
Sabah Kasmi
Coen Ruben De
Koker Stefaan De
Shrinivas Dumbre
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Etherna Immunotherapies Nv, Sabah Kasmi, Coen Ruben De, Koker Stefaan De, Shrinivas Dumbre filed Critical Etherna Immunotherapies Nv
Publication of IL325487A publication Critical patent/IL325487A/he

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/125Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51Nanocapsules; Nanoparticles
    • A61K9/5107Excipients; Inactive ingredients
    • A61K9/5123Organic compounds, e.g. fats, sugars

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nanotechnology (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
IL325487A 2023-07-06 2025-12-21 ליפידים הניתנים ליינון IL325487A (he)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP23183820 2023-07-06
PCT/EP2024/069013 WO2025008510A1 (en) 2023-07-06 2024-07-05 Ionizable lipids

Publications (1)

Publication Number Publication Date
IL325487A true IL325487A (he) 2026-02-01

Family

ID=87158040

Family Applications (1)

Application Number Title Priority Date Filing Date
IL325487A IL325487A (he) 2023-07-06 2025-12-21 ליפידים הניתנים ליינון

Country Status (6)

Country Link
KR (1) KR20260033596A (he)
CN (1) CN121843927A (he)
AU (1) AU2024290779A1 (he)
IL (1) IL325487A (he)
TW (1) TW202517616A (he)
WO (1) WO2025008510A1 (he)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2026003582A2 (en) 2024-06-27 2026-01-02 Axelyf ehf. Lipids and lipid nanoparticles

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1113364B (it) * 1979-05-10 1986-01-20 Montedison Spa N,n'-di-(idrossi-fenil)derivati della piperrazina e loro impiego come stabilizzanti per polimeri
JP3256601B2 (ja) * 1993-07-21 2002-02-12 塩野義製薬株式会社 抗潰瘍活性を有するベンゾジアゼピン誘導体
WO2007091441A1 (ja) * 2006-02-09 2007-08-16 Konica Minolta Medical & Graphic, Inc. 感光性組成物、感光性平版印刷版材料及び平版印刷版材料の記録方法
CA3155075A1 (en) * 2019-10-18 2021-04-22 Michael Mitchell Lipid nanoparticles and formulations thereof for car mrna delivery
IL303659A (he) * 2020-12-23 2023-08-01 Etherna Immunotherapies Nv שומנים מייננים

Also Published As

Publication number Publication date
WO2025008510A1 (en) 2025-01-09
KR20260033596A (ko) 2026-03-10
CN121843927A (zh) 2026-04-10
TW202517616A (zh) 2025-05-01
AU2024290779A1 (en) 2026-02-26

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