IL325331A - Tyk2 inhibitors and compositions and methods thereof - Google Patents

Tyk2 inhibitors and compositions and methods thereof

Info

Publication number
IL325331A
IL325331A IL325331A IL32533125A IL325331A IL 325331 A IL325331 A IL 325331A IL 325331 A IL325331 A IL 325331A IL 32533125 A IL32533125 A IL 32533125A IL 325331 A IL325331 A IL 325331A
Authority
IL
Israel
Prior art keywords
compositions
methods
tyk2 inhibitors
tyk2
inhibitors
Prior art date
Application number
IL325331A
Other languages
Hebrew (he)
Inventor
Li Xiaodong
Su Lin
Wan Zhaokui
Grewal Gurmit
Lawrence Vazquez Michael
Lin Weiyu
Original Assignee
Lynk Pharmaceuticals Co Ltd
Li Xiaodong
Su Lin
Wan Zhaokui
Grewal Gurmit
Lawrence Vazquez Michael
Lin Weiyu
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lynk Pharmaceuticals Co Ltd, Li Xiaodong, Su Lin, Wan Zhaokui, Grewal Gurmit, Lawrence Vazquez Michael, Lin Weiyu filed Critical Lynk Pharmaceuticals Co Ltd
Publication of IL325331A publication Critical patent/IL325331A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IL325331A 2023-06-15 2025-12-14 Tyk2 inhibitors and compositions and methods thereof IL325331A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/CN2023/100508 WO2024254832A1 (en) 2023-06-15 2023-06-15 Tyk2 inhibitors and compositions and methods thereof
PCT/CN2024/099407 WO2024255886A1 (en) 2023-06-15 2024-06-14 Tyk2 inhibitors and compositions and methods thereof

Publications (1)

Publication Number Publication Date
IL325331A true IL325331A (en) 2026-02-01

Family

ID=93851118

Family Applications (1)

Application Number Title Priority Date Filing Date
IL325331A IL325331A (en) 2023-06-15 2025-12-14 Tyk2 inhibitors and compositions and methods thereof

Country Status (4)

Country Link
AU (1) AU2024304652A1 (en)
IL (1) IL325331A (en)
TW (1) TW202502764A (en)
WO (2) WO2024254832A1 (en)

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013047813A1 (en) * 2011-09-30 2013-04-04 大鵬薬品工業株式会社 1,2,4-triazine-6-carboxamide derivative
WO2013117649A1 (en) * 2012-02-10 2013-08-15 Galapagos Nv Imidazo [4, 5 -c] pyridine derivatives useful for the treatment of degenerative and inflammatory diseases
US9040530B2 (en) * 2012-06-22 2015-05-26 Portola Pharmaceuticals, Inc. 1,2,4-triazine-6-carboxamide kinase inhibitors
JP6430390B2 (en) * 2012-11-20 2018-11-28 ジェネンテック, インコーポレイテッド Aminopyrimidine compounds as inhibitors of EGFR mutants containing T790M
CN111484480B (en) * 2019-01-29 2023-08-11 上海翰森生物医药科技有限公司 A polycyclic derivative inhibitor, its preparation method and application
CN115466257A (en) * 2021-06-11 2022-12-13 爱科诺生物医药(香港)有限公司 Compound with TYK2 inhibitory activity, pharmaceutical composition containing same, and application thereof
TW202317561A (en) * 2021-07-01 2023-05-01 美商羅曼德生物治療公司 Compounds having 1h-pyrazolo[4,3-c]pyridin-6-amino as therapeutic agents
KR20240120732A (en) * 2021-12-16 2024-08-07 링크 파마슈티컬스 컴퍼니 리미티드 TYK2 inhibitors, compositions and methods thereof

Also Published As

Publication number Publication date
WO2024254832A1 (en) 2024-12-19
AU2024304652A1 (en) 2026-01-22
WO2024255886A1 (en) 2024-12-19
TW202502764A (en) 2025-01-16

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