IL325215A - קומפלקס חלבונים מרובה מטרות ושיטות לשימוש בו - Google Patents

קומפלקס חלבונים מרובה מטרות ושיטות לשימוש בו

Info

Publication number
IL325215A
IL325215A IL325215A IL32521525A IL325215A IL 325215 A IL325215 A IL 325215A IL 325215 A IL325215 A IL 325215A IL 32521525 A IL32521525 A IL 32521525A IL 325215 A IL325215 A IL 325215A
Authority
IL
Israel
Prior art keywords
methods
protein complex
targeting protein
targeting
complex
Prior art date
Application number
IL325215A
Other languages
English (en)
Original Assignee
Fbd Biologics Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fbd Biologics Ltd filed Critical Fbd Biologics Ltd
Publication of IL325215A publication Critical patent/IL325215A/he

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/7051—T-cell receptor (TcR)-CD3 complex
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70521—CD28, CD152
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70596—Molecules with a "CD"-designation not provided for elsewhere
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cell Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
IL325215A 2023-06-22 2025-12-08 קומפלקס חלבונים מרובה מטרות ושיטות לשימוש בו IL325215A (he)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202363509693P 2023-06-22 2023-06-22
PCT/CN2024/100387 WO2024260419A1 (en) 2023-06-22 2024-06-20 Multi-targeting protein complex and methods of use thereof

Publications (1)

Publication Number Publication Date
IL325215A true IL325215A (he) 2026-02-01

Family

ID=93934897

Family Applications (1)

Application Number Title Priority Date Filing Date
IL325215A IL325215A (he) 2023-06-22 2025-12-08 קומפלקס חלבונים מרובה מטרות ושיטות לשימוש בו

Country Status (6)

Country Link
KR (1) KR20260027895A (he)
CN (1) CN121013868A (he)
AU (1) AU2024314312A1 (he)
IL (1) IL325215A (he)
TW (1) TW202515923A (he)
WO (1) WO2024260419A1 (he)

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LT3565579T (lt) * 2017-01-05 2023-09-11 Kahr Medical Ltd. Pd1-41bbl sulietas baltymas ir jo panaudojimo būdai
WO2018127919A1 (en) * 2017-01-05 2018-07-12 Kahr Medical Ltd. A SIRP1 alpha-41BBL FUSION PROTEIN AND METHODS OF USE THEREOF
JP7260477B2 (ja) * 2017-02-27 2023-04-18 シャタック ラボ，インコーポレイテッド Ｔｉｇｉｔ及びｌｉｇｈｔベースのキメラタンパク質
WO2019154415A1 (en) * 2018-02-06 2019-08-15 I-Mab Antibodies to t cell immunoreceptor with ig and itim domains (tigit) and uses thereof
CN114375310A (zh) * 2019-07-11 2022-04-19 卡尔医学有限公司 数个异二聚体及其数个使用方法
EP4026846A4 (en) * 2019-09-03 2023-09-13 Bio-Thera Solutions, Ltd. Anti-tigit immunosuppressant and application thereof
AU2022224335B2 (en) * 2021-02-19 2025-12-18 Shaperon Inc. Bispecific single domain antibody to pd-l1 and cd47 and use thereof

Also Published As

Publication number Publication date
KR20260027895A (ko) 2026-03-03
WO2024260419A1 (en) 2024-12-26
TW202515923A (zh) 2025-04-16
CN121013868A (zh) 2025-11-25
AU2024314312A1 (en) 2025-10-30

Similar Documents

Publication Publication Date Title
PL4232463T3 (pl) Białka fuzyjne interleukiny-2-fc i sposoby ich stosowania
GB202019709D0 (en) Anti-Coronavirus antibodies and methods of use
AU2021365129A9 (en) Interleukin-2-fc fusion proteins and methods of use
IL316368A (he) נוגדנים אנטי- tl1a ושיטות לשימוש בהם
IL304381A (he) חלבוני ממברנה הטרודימרים מסוג 1 (type 1) ושיטות לשימוש בהם
IL314210A (he) קומפלקס חלבון ממוקד cd47/pd-l1- ושיטות לשימוש בו
SI4200018T1 (sl) Protitelesa proti-PAR-2 in postopki njihove uporabe
IL315845A (he) נוגדנים אנטי-דקטין-1 ושיטות לשימוש בהם
IL317690A (he) נוגדנים אנטי- gpnmbושיטות לשימוש בהם
IL304233A (he) חלבוני איחוי סיאלידאז-נוגדן- her2ושיטות לשימוש בהם
IL318694A (he) נוגדנים כנגד ccr8 ושיטות לשימוש בהם
IL325215A (he) קומפלקס חלבונים מרובה מטרות ושיטות לשימוש בו
IL308260A (he) נוגדנים נגד טיגיט ודרכי השימוש בהם
IL304228A (he) חלבוני איחוי סיאלידאז-נוגדן-pd-1 ושיטות לשימוש בהם
CA3291261A1 (en) Multi-targeting protein complex and methods of use thereof
AU2023413056A1 (en) Engineered proteins and methods of use thereof
IL314129A (he) חומרים ושיטות של חלבונים קושרי il-1beta
GB202218501D0 (en) Mutated CD200 proteins and methods of use therof
CA3286944A1 (en) Abeta-targeting proteins and methods of use
HK40090206A (en) B7h3-targeting proteins and methods of use thereof
IL318357A (he) נוגדני anti-il27r ושיטות השימוש בהם
IL316700A (he) נוגדני anti-bmp9 ושיטות השימוש בהם
IL316894A (he) נוגדני anti-tnfr2 ושיטות השימוש בהם
IL321679A (he) נוגדני אנטי-ror2 ושיטות לשימוש
CA3289326A1 (en) Raf-mek protein complex modulators and methods of use thereof