IL324897A - אגוניסטים של trem2 - Google Patents

אגוניסטים של trem2

Info

Publication number
IL324897A
IL324897A IL324897A IL32489725A IL324897A IL 324897 A IL324897 A IL 324897A IL 324897 A IL324897 A IL 324897A IL 32489725 A IL32489725 A IL 32489725A IL 324897 A IL324897 A IL 324897A
Authority
IL
Israel
Prior art keywords
trem2
agonists
trem2 agonists
Prior art date
Application number
IL324897A
Other languages
English (en)
Inventor
Stefan Berchtold
Virginie Sacha Brom
Julie Charpentier
Francesco Maria Emilia Di
Guido Galley
Luca Claudio Gobbi
Wolfgang Guba
Roland Johann Humm
Marie-Paule Imhoff
Fionn Susannah O'hara
Ang?Lique Patiny-Adam
Flore Marie Aude Reggiani
Nicolas Zeidan
Original Assignee
Hoffmann La Roche
Stefan Berchtold
Virginie Sacha Brom
Julie Charpentier
Francesco Maria Emilia Di
Guido Galley
Luca Claudio Gobbi
Wolfgang Guba
Roland Johann Humm
Imhoff Marie Paule
Ohara Fionn Susannah
Patiny Adam Ang?Lique
Flore Marie Aude Reggiani
Nicolas Zeidan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche, Stefan Berchtold, Virginie Sacha Brom, Julie Charpentier, Francesco Maria Emilia Di, Guido Galley, Luca Claudio Gobbi, Wolfgang Guba, Roland Johann Humm, Imhoff Marie Paule, Ohara Fionn Susannah, Patiny Adam Ang?Lique, Flore Marie Aude Reggiani, Nicolas Zeidan filed Critical Hoffmann La Roche
Publication of IL324897A publication Critical patent/IL324897A/he

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Hydrogenated Pyridines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IL324897A 2023-06-19 2025-11-24 אגוניסטים של trem2 IL324897A (he)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP23179957 2023-06-19
EP23211237 2023-11-21
PCT/EP2024/066833 WO2024260929A1 (en) 2023-06-19 2024-06-17 Trem2 agonists

Publications (1)

Publication Number Publication Date
IL324897A true IL324897A (he) 2026-01-01

Family

ID=91621082

Family Applications (1)

Application Number Title Priority Date Filing Date
IL324897A IL324897A (he) 2023-06-19 2025-11-24 אגוניסטים של trem2

Country Status (7)

Country Link
CN (1) CN121335893A (he)
AR (1) AR132992A1 (he)
AU (1) AU2024312352A1 (he)
CO (1) CO2025018165A2 (he)
IL (1) IL324897A (he)
TW (1) TW202515878A (he)
WO (1) WO2024260929A1 (he)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12459953B2 (en) 2024-01-04 2025-11-04 Muna Therapeutics Aps TREM2 modulators
TW202542156A (zh) 2024-01-04 2025-11-01 丹麥商穆納醫療有限責任公司 Trem2調節劑

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010000032A1 (en) * 2008-07-02 2010-01-07 Avexa Limited Compounds having antiviral properties
US20250042897A1 (en) * 2021-11-09 2025-02-06 Vigil Neuroscience, Inc. Heterocyclic compounds as triggering receptor expressed on myeloid cells 2 agonists and methods of use

Also Published As

Publication number Publication date
AR132992A1 (es) 2025-08-13
AU2024312352A1 (en) 2025-12-11
CO2025018165A2 (es) 2026-01-23
TW202515878A (zh) 2025-04-16
CN121335893A (zh) 2026-01-13
WO2024260929A1 (en) 2024-12-26

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