IL324784A - Humanized il-10 receptor binding molecules and methods of use - Google Patents

Humanized il-10 receptor binding molecules and methods of use

Info

Publication number
IL324784A
IL324784A IL324784A IL32478425A IL324784A IL 324784 A IL324784 A IL 324784A IL 324784 A IL324784 A IL 324784A IL 32478425 A IL32478425 A IL 32478425A IL 324784 A IL324784 A IL 324784A
Authority
IL
Israel
Prior art keywords
humanized
methods
receptor binding
binding molecules
molecules
Prior art date
Application number
IL324784A
Other languages
Hebrew (he)
Inventor
Patrick L Lupardus
Andrew Morin
Mahalakshmi Ramadass
Deepti Rokkam
Michael Totagrande
Sandro Vivano
Original Assignee
Synthekine Inc
Patrick L Lupardus
Andrew Morin
Mahalakshmi Ramadass
Deepti Rokkam
Michael Totagrande
Sandro Vivano
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthekine Inc, Patrick L Lupardus, Andrew Morin, Mahalakshmi Ramadass, Deepti Rokkam, Michael Totagrande, Sandro Vivano filed Critical Synthekine Inc
Publication of IL324784A publication Critical patent/IL324784A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/569—Single domain, e.g. dAb, sdAb, VHH, VNAR or nanobody®
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/75—Agonist effect on antigen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
IL324784A 2023-06-07 2025-11-19 Humanized il-10 receptor binding molecules and methods of use IL324784A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202363506798P 2023-06-07 2023-06-07
US202363511122P 2023-06-29 2023-06-29
PCT/US2024/033162 WO2024254567A2 (en) 2023-06-07 2024-06-07 Humanized il-10 receptor binding molecules and methods of use

Publications (1)

Publication Number Publication Date
IL324784A true IL324784A (en) 2026-01-01

Family

ID=93796492

Family Applications (1)

Application Number Title Priority Date Filing Date
IL324784A IL324784A (en) 2023-06-07 2025-11-19 Humanized il-10 receptor binding molecules and methods of use

Country Status (3)

Country Link
AU (1) AU2024286534A1 (en)
IL (1) IL324784A (en)
WO (1) WO2024254567A2 (en)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107216389B (en) * 2016-03-18 2022-03-29 和迈生物科技有限公司 anti-PD-L1 nano antibody and coding sequence and application thereof
JP7743500B2 (en) * 2020-08-05 2025-09-24 シンセカイン インコーポレイテッド IL10 receptor binding molecules and methods of use

Also Published As

Publication number Publication date
WO2024254567A2 (en) 2024-12-12
AU2024286534A1 (en) 2025-12-04
WO2024254567A3 (en) 2025-02-27

Similar Documents

Publication Publication Date Title
IL305944A (en) Agonistic anti-il-2r antibodies and methods of use
IL275243A (en) Bispecific antigen binding molecules that bind leptin receptor and/or gp130, and methods of use thereof
IL317655A (en) Fcrn/antigen-binding molecules and methods of use
EP4192880A4 (en) Il10 receptor binding molecules and methods of use
IL316368A (en) Anti-tl1a antibodies and methods of use thereof
IL316065A (en) Anti-cd28 antibodies and methods of use thereof
IL315714A (en) Bispecific antibody fusion molecules and methods of use thereof
IL315845A (en) Anti-dectin-1 antibodies and methods of use thereof
IL319674A (en) Humanized anti-il-1r3 antibody and methods of use
IL317690A (en) Anti-gpnmb antibodies and methods of use thereof
IL318694A (en) Anti-ccr8 antibodies and methods of use
IL324784A (en) Humanized il-10 receptor binding molecules and methods of use
CA3293252A1 (en) Humanized il-10 receptor binding molecules and methods of use
GB202319605D0 (en) Monovalent binding molecules and methods of use
IL317637A (en) Anti-steap1 antigen-binding molecules and uses thereof
IL319590A (en) Multispecific antibodies and methods of use thereof
CA3284529A1 (en) Antigen binding molecules and methods of use
IL320671A (en) Anti-fgfr3 antibodies and antigen-binding fragments and methods of use thereof
IL318357A (en) Anti- il27r antibodies and methods of use thereof
IL316700A (en) Anti-bmp9 antibodies and methods of use thereof
IL316894A (en) Anti-tnfr2 antibodies and methods of use thereof
IL321679A (en) Anti-ror-2 antibodies and methods of use
HK40104314A (en) Anti-cd3 antibodies and methods of use thereof
EP4010697A4 (en) Antigen binding molecules and methods of screening thereof
CA3288202A1 (en) Il-10 receptor antibodies and methods of use thereof