IL324764A - מעכבי prmt5 - Google Patents

מעכבי prmt5

Info

Publication number
IL324764A
IL324764A IL324764A IL32476425A IL324764A IL 324764 A IL324764 A IL 324764A IL 324764 A IL324764 A IL 324764A IL 32476425 A IL32476425 A IL 32476425A IL 324764 A IL324764 A IL 324764A
Authority
IL
Israel
Prior art keywords
prmt5 inhibitors
prmt5
inhibitors
Prior art date
Application number
IL324764A
Other languages
English (en)
Original Assignee
Ryvu Therapeutics S A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ryvu Therapeutics S A filed Critical Ryvu Therapeutics S A
Publication of IL324764A publication Critical patent/IL324764A/he

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04Ortho-condensed systems
    • C07D491/044Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
    • C07D491/048Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being five-membered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D519/00Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IL324764A 2023-05-24 2025-11-18 מעכבי prmt5 IL324764A (he)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP23461596 2023-05-24
EP24169443 2024-04-10
PCT/EP2024/064279 WO2024240894A1 (en) 2023-05-24 2024-05-23 Prmt5 inhibitors

Publications (1)

Publication Number Publication Date
IL324764A true IL324764A (he) 2026-01-01

Family

ID=91193326

Family Applications (1)

Application Number Title Priority Date Filing Date
IL324764A IL324764A (he) 2023-05-24 2025-11-18 מעכבי prmt5

Country Status (4)

Country Link
AU (1) AU2024275020A1 (he)
IL (1) IL324764A (he)
MX (1) MX2025013985A (he)
WO (1) WO2024240894A1 (he)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN121079300A (zh) 2023-04-21 2025-12-05 吉利德科学公司 Prmt5抑制剂及其用途

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PE20231312A1 (es) * 2020-11-24 2023-08-24 Amgen Inc Derivados triciclicos de carboxamida como inhibidores de la prmt5
MX2023009222A (es) * 2021-02-04 2023-09-11 Amgen Inc Inhibidores tricíclicos-amido-bicíclicos de prmt5.
US20240368153A1 (en) * 2021-07-02 2024-11-07 Mirati Therapeutics, Inc. Aminopyridine-based MTA-Cooperative PRMT5 Inhibitors
WO2024074611A1 (en) * 2022-10-05 2024-04-11 Ryvu Therapeutics S.A. Prmt5 inhibitors

Also Published As

Publication number Publication date
AU2024275020A1 (en) 2025-11-13
MX2025013985A (es) 2026-01-07
WO2024240894A1 (en) 2024-11-28

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