IL324764A - מעכבי prmt5 - Google Patents
מעכבי prmt5Info
- Publication number
- IL324764A IL324764A IL324764A IL32476425A IL324764A IL 324764 A IL324764 A IL 324764A IL 324764 A IL324764 A IL 324764A IL 32476425 A IL32476425 A IL 32476425A IL 324764 A IL324764 A IL 324764A
- Authority
- IL
- Israel
- Prior art keywords
- prmt5 inhibitors
- prmt5
- inhibitors
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
- C07D491/048—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being five-membered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP23461596 | 2023-05-24 | ||
| EP24169443 | 2024-04-10 | ||
| PCT/EP2024/064279 WO2024240894A1 (en) | 2023-05-24 | 2024-05-23 | Prmt5 inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL324764A true IL324764A (he) | 2026-01-01 |
Family
ID=91193326
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL324764A IL324764A (he) | 2023-05-24 | 2025-11-18 | מעכבי prmt5 |
Country Status (4)
| Country | Link |
|---|---|
| AU (1) | AU2024275020A1 (he) |
| IL (1) | IL324764A (he) |
| MX (1) | MX2025013985A (he) |
| WO (1) | WO2024240894A1 (he) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN121079300A (zh) | 2023-04-21 | 2025-12-05 | 吉利德科学公司 | Prmt5抑制剂及其用途 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PE20231312A1 (es) * | 2020-11-24 | 2023-08-24 | Amgen Inc | Derivados triciclicos de carboxamida como inhibidores de la prmt5 |
| MX2023009222A (es) * | 2021-02-04 | 2023-09-11 | Amgen Inc | Inhibidores tricíclicos-amido-bicíclicos de prmt5. |
| US20240368153A1 (en) * | 2021-07-02 | 2024-11-07 | Mirati Therapeutics, Inc. | Aminopyridine-based MTA-Cooperative PRMT5 Inhibitors |
| WO2024074611A1 (en) * | 2022-10-05 | 2024-04-11 | Ryvu Therapeutics S.A. | Prmt5 inhibitors |
-
2024
- 2024-05-23 AU AU2024275020A patent/AU2024275020A1/en active Pending
- 2024-05-23 WO PCT/EP2024/064279 patent/WO2024240894A1/en active Pending
-
2025
- 2025-11-18 IL IL324764A patent/IL324764A/he unknown
- 2025-11-21 MX MX2025013985A patent/MX2025013985A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU2024275020A1 (en) | 2025-11-13 |
| MX2025013985A (es) | 2026-01-07 |
| WO2024240894A1 (en) | 2024-11-28 |
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