IL324630A - אנלוגים של איזואנדרוגרופולידים ושיטה לטיפול בהם - Google Patents

אנלוגים של איזואנדרוגרופולידים ושיטה לטיפול בהם

Info

Publication number
IL324630A
IL324630A IL324630A IL32463025A IL324630A IL 324630 A IL324630 A IL 324630A IL 324630 A IL324630 A IL 324630A IL 32463025 A IL32463025 A IL 32463025A IL 324630 A IL324630 A IL 324630A
Authority
IL
Israel
Prior art keywords
isoandrographolide
analogs
treatment
same
isoandrographolide analogs
Prior art date
Application number
IL324630A
Other languages
English (en)
Inventor
Subbaraju Venkata Gottumukkala
Kiran Cherukupalli
Bryan Hurst Norman
Prabhakar K Jadhav
Sotirios K Karathanasis
Goutam Mandal
Indranil Mukhopadhyay
Original Assignee
Enveda Therapeutics Inc
Subbaraju Venkata Gottumukkala
Kiran Cherukupalli
Bryan Hurst Norman
Prabhakar K Jadhav
Sotirios K Karathanasis
Goutam Mandal
Indranil Mukhopadhyay
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Enveda Therapeutics Inc, Subbaraju Venkata Gottumukkala, Kiran Cherukupalli, Bryan Hurst Norman, Prabhakar K Jadhav, Sotirios K Karathanasis, Goutam Mandal, Indranil Mukhopadhyay filed Critical Enveda Therapeutics Inc
Publication of IL324630A publication Critical patent/IL324630A/he

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04Ortho-condensed systems
    • C07D491/044Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
    • C07D491/048Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being five-membered

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL324630A 2023-05-18 2025-11-12 אנלוגים של איזואנדרוגרופולידים ושיטה לטיפול בהם IL324630A (he)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202363503156P 2023-05-18 2023-05-18
PCT/US2024/030111 WO2024239001A2 (en) 2023-05-18 2024-05-17 Isoandrographolide analogs and method for treatment using the same

Publications (1)

Publication Number Publication Date
IL324630A true IL324630A (he) 2026-01-01

Family

ID=93519990

Family Applications (1)

Application Number Title Priority Date Filing Date
IL324630A IL324630A (he) 2023-05-18 2025-11-12 אנלוגים של איזואנדרוגרופולידים ושיטה לטיפול בהם

Country Status (5)

Country Link
CN (1) CN121532179A (he)
AU (1) AU2024271399A1 (he)
IL (1) IL324630A (he)
TW (1) TW202509038A (he)
WO (1) WO2024239001A2 (he)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU4376396A (en) * 1994-12-06 1996-06-26 Paracelsian, Inc. Use of andrographolide compounds to treat or prevent pathogenicity of diseases
CN101028260A (zh) * 2007-02-06 2007-09-05 中国药科大学 取代的异穿心莲内酯衍生物的用途
US20150352075A1 (en) * 2013-04-22 2015-12-10 Innobioscience, Llc Treatment of Alzheimer's and Cognitive Impairment With Andrographolides
US10064841B1 (en) * 2018-01-08 2018-09-04 King Saud University Isoandrographolide-19-propionate for treatment of non-alcoholic fatty liver disease (NAFLD)
WO2019166003A1 (zh) * 2018-03-02 2019-09-06 郑州大学 14-脱氧-11,12-脱氢-8,12-环氧或7,8-烯-穿心莲内酯及其15位取代衍生物和用途

Also Published As

Publication number Publication date
WO2024239001A2 (en) 2024-11-21
AU2024271399A1 (en) 2025-12-18
WO2024239001A3 (en) 2025-03-06
CN121532179A (zh) 2026-02-13
TW202509038A (zh) 2025-03-01

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