IL323959A - תולדות פירולופירידין כמאפננים אלוסטריים חיוביים של קולטן אצטילכולין המוסקריני m4 - Google Patents
תולדות פירולופירידין כמאפננים אלוסטריים חיוביים של קולטן אצטילכולין המוסקריני m4Info
- Publication number
- IL323959A IL323959A IL323959A IL32395925A IL323959A IL 323959 A IL323959 A IL 323959A IL 323959 A IL323959 A IL 323959A IL 32395925 A IL32395925 A IL 32395925A IL 323959 A IL323959 A IL 323959A
- Authority
- IL
- Israel
- Prior art keywords
- pyridin
- compound
- pharmaceutically acceptable
- dihydro
- dihydrothiazolo
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Epidemiology (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202363496806P | 2023-04-18 | 2023-04-18 | |
| US202363610184P | 2023-12-14 | 2023-12-14 | |
| PCT/US2024/025144 WO2024220633A1 (en) | 2023-04-18 | 2024-04-18 | Pyrrolopyridine derivatives as positive allosteric modulators of the muscarinic acetylcholine receptor m4 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL323959A true IL323959A (he) | 2025-12-01 |
Family
ID=91027396
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL323959A IL323959A (he) | 2023-04-18 | 2025-10-15 | תולדות פירולופירידין כמאפננים אלוסטריים חיוביים של קולטן אצטילכולין המוסקריני m4 |
Country Status (6)
| Country | Link |
|---|---|
| KR (1) | KR20250172585A (he) |
| CN (1) | CN121002031A (he) |
| AU (1) | AU2024257614A1 (he) |
| IL (1) | IL323959A (he) |
| MX (1) | MX2025012360A (he) |
| WO (1) | WO2024220633A1 (he) |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL89351A0 (en) * | 1988-03-14 | 1989-09-10 | Lundbeck & Co As H | 4,5,6,7-tetrahydroisothiazolo(4,5-c)pyridines,process for their preparation and pharmaceutical compositions containing them |
| US10329289B2 (en) * | 2015-12-23 | 2019-06-25 | Merck Sharp & Dohme Corp. | 6,7-dihydro-5H-pyrrolo[3,4-B]pyridin-5-one allosteric modulators of the M4 muscarinic acetylcholine receptor |
-
2024
- 2024-04-18 AU AU2024257614A patent/AU2024257614A1/en active Pending
- 2024-04-18 CN CN202480026241.5A patent/CN121002031A/zh active Pending
- 2024-04-18 WO PCT/US2024/025144 patent/WO2024220633A1/en not_active Ceased
- 2024-04-18 KR KR1020257034533A patent/KR20250172585A/ko active Pending
-
2025
- 2025-10-15 IL IL323959A patent/IL323959A/he unknown
- 2025-10-16 MX MX2025012360A patent/MX2025012360A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| KR20250172585A (ko) | 2025-12-09 |
| CN121002031A (zh) | 2025-11-21 |
| AU2024257614A1 (en) | 2025-10-02 |
| WO2024220633A1 (en) | 2024-10-24 |
| MX2025012360A (es) | 2025-11-03 |
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