IL322685A - תבניות פירוק דנ" א נטולי תאים שמקורן בדלפי מבדילות בין תתי-סוגים היסטולוגיים של סרטן ריאות בצורה לא פולשנית - Google Patents

תבניות פירוק דנ" א נטולי תאים שמקורן בדלפי מבדילות בין תתי-סוגים היסטולוגיים של סרטן ריאות בצורה לא פולשנית

Info

Publication number
IL322685A
IL322685A IL322685A IL32268525A IL322685A IL 322685 A IL322685 A IL 322685A IL 322685 A IL322685 A IL 322685A IL 32268525 A IL32268525 A IL 32268525A IL 322685 A IL322685 A IL 322685A
Authority
IL
Israel
Prior art keywords
cfdna
coverage
transcription factor
fragment
cancer
Prior art date
Application number
IL322685A
Other languages
English (en)
Original Assignee
Delfi Diagnostics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Delfi Diagnostics Inc filed Critical Delfi Diagnostics Inc
Publication of IL322685A publication Critical patent/IL322685A/he

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869Methods for sequencing
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B30/00ICT specially adapted for sequence analysis involving nucleotides or amino acids
    • G16B30/10Sequence alignment; Homology search
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • G16B40/20Supervised data analysis
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/20ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medical Informatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Public Health (AREA)
  • Data Mining & Analysis (AREA)
  • Pathology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Databases & Information Systems (AREA)
  • Theoretical Computer Science (AREA)
  • Evolutionary Biology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Evolutionary Computation (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Hospice & Palliative Care (AREA)
  • Bioethics (AREA)
  • Artificial Intelligence (AREA)
  • Primary Health Care (AREA)
  • Oncology (AREA)
  • Software Systems (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
IL322685A 2023-02-13 2024-02-12 תבניות פירוק דנ" א נטולי תאים שמקורן בדלפי מבדילות בין תתי-סוגים היסטולוגיים של סרטן ריאות בצורה לא פולשנית IL322685A (he)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US202363445284P 2023-02-13 2023-02-13
US202363470101P 2023-05-31 2023-05-31
US202363528237P 2023-07-21 2023-07-21
PCT/US2024/015444 WO2024173277A2 (en) 2023-02-13 2024-02-12 Delfi-derived cell-free dna fragmentation patterns differentiate histologic subtypes of lung cancers in a non-invasive manner

Publications (1)

Publication Number Publication Date
IL322685A true IL322685A (he) 2025-10-01

Family

ID=92420632

Family Applications (1)

Application Number Title Priority Date Filing Date
IL322685A IL322685A (he) 2023-02-13 2024-02-12 תבניות פירוק דנ" א נטולי תאים שמקורן בדלפי מבדילות בין תתי-סוגים היסטולוגיים של סרטן ריאות בצורה לא פולשנית

Country Status (9)

Country Link
EP (1) EP4665867A2 (he)
JP (1) JP2026506641A (he)
KR (1) KR20250151418A (he)
CN (1) CN120752348A (he)
AU (1) AU2024223105A1 (he)
CO (1) CO2025012211A2 (he)
IL (1) IL322685A (he)
MX (1) MX2025009394A (he)
WO (1) WO2024173277A2 (he)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2026051992A1 (en) * 2024-09-04 2026-03-12 Centre For Novostics Fragmentomics in cerebrospinal fluid

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20240015054A (ko) * 2020-12-21 2024-02-02 더 존스 홉킨스 유니버시티 무세포 dna 단편화를 이용한 폐암 검출
CA3214321A1 (en) * 2021-04-08 2022-10-13 Nicholas C. Dracopoli Method of detecting cancer using genome-wide cfdna fragmentation profiles
EP4320618A4 (en) * 2021-04-08 2025-08-27 Fred Hutchinson Cancer Center METHOD FOR ANALYZING CELL-FREE DNA SEQUENCE DATA TO EXAMINE NUCLEOSOME PROTECTION AND CHROMATIN ACCESSIBILITY

Also Published As

Publication number Publication date
CN120752348A (zh) 2025-10-03
EP4665867A2 (en) 2025-12-24
JP2026506641A (ja) 2026-02-25
MX2025009394A (es) 2025-11-03
KR20250151418A (ko) 2025-10-21
WO2024173277A2 (en) 2024-08-22
WO2024173277A3 (en) 2024-10-24
CO2025012211A2 (es) 2025-09-29
AU2024223105A1 (en) 2025-08-28

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