IL321828A - תרכובות ספירוציקלואלקיל ותכשירי רוקחות המווסתים ikzf2 - Google Patents
תרכובות ספירוציקלואלקיל ותכשירי רוקחות המווסתים ikzf2Info
- Publication number
- IL321828A IL321828A IL321828A IL32182825A IL321828A IL 321828 A IL321828 A IL 321828A IL 321828 A IL321828 A IL 321828A IL 32182825 A IL32182825 A IL 32182825A IL 321828 A IL321828 A IL 321828A
- Authority
- IL
- Israel
- Prior art keywords
- spirocycloalkyl
- compounds
- pharmaceutical compositions
- ikzf2
- modulate
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
- C07D491/107—Spiro-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202363478449P | 2023-01-04 | 2023-01-04 | |
| PCT/US2024/010179 WO2024148088A1 (en) | 2023-01-04 | 2024-01-03 | Spirocycloalkyl compounds and pharmaceutical compositions that modulate ikzf2 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL321828A true IL321828A (he) | 2025-08-01 |
Family
ID=89898249
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL321828A IL321828A (he) | 2023-01-04 | 2024-01-03 | תרכובות ספירוציקלואלקיל ותכשירי רוקחות המווסתים ikzf2 |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP4646409A1 (he) |
| JP (1) | JP2026502995A (he) |
| KR (1) | KR20250123937A (he) |
| CN (1) | CN120677151A (he) |
| AU (1) | AU2024206123A1 (he) |
| IL (1) | IL321828A (he) |
| MX (1) | MX2025007760A (he) |
| WO (1) | WO2024148088A1 (he) |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5262564A (en) | 1992-10-30 | 1993-11-16 | Octamer, Inc. | Sulfinic acid adducts of organo nitroso compounds useful as retroviral inactivating agents anti-retroviral agents and anti-tumor agents |
| DK3820573T3 (da) * | 2018-07-10 | 2023-10-23 | Novartis Ag | 3-(5-hydroxy-1-oxoisoindolin-2-yl)piperidin-2,6-dion-derivativer og anvendelse deraf ved behandling af ikaros family zinc finger 2 (ikzf2)-afhængige sygdomme |
-
2024
- 2024-01-03 AU AU2024206123A patent/AU2024206123A1/en active Pending
- 2024-01-03 KR KR1020257025781A patent/KR20250123937A/ko active Pending
- 2024-01-03 JP JP2025539376A patent/JP2026502995A/ja active Pending
- 2024-01-03 CN CN202480012176.0A patent/CN120677151A/zh active Pending
- 2024-01-03 WO PCT/US2024/010179 patent/WO2024148088A1/en not_active Ceased
- 2024-01-03 EP EP24704283.1A patent/EP4646409A1/en active Pending
- 2024-01-03 IL IL321828A patent/IL321828A/he unknown
-
2025
- 2025-07-01 MX MX2025007760A patent/MX2025007760A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP4646409A1 (en) | 2025-11-12 |
| JP2026502995A (ja) | 2026-01-27 |
| CN120677151A (zh) | 2025-09-19 |
| MX2025007760A (es) | 2025-10-01 |
| WO2024148088A1 (en) | 2024-07-11 |
| AU2024206123A1 (en) | 2025-07-17 |
| KR20250123937A (ko) | 2025-08-18 |
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