IL321537A - ליגאזות rna דו-גדיליות מהונדסות ושימושיהן - Google Patents
ליגאזות rna דו-גדיליות מהונדסות ושימושיהןInfo
- Publication number
- IL321537A IL321537A IL321537A IL32153725A IL321537A IL 321537 A IL321537 A IL 321537A IL 321537 A IL321537 A IL 321537A IL 32153725 A IL32153725 A IL 32153725A IL 321537 A IL321537 A IL 321537A
- Authority
- IL
- Israel
- Prior art keywords
- strand rna
- engineered double
- rna ligases
- ligases
- engineered
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/93—Ligases (6)
Landscapes
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Medicinal Chemistry (AREA)
- Enzymes And Modification Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP22215201 | 2022-12-20 | ||
| PCT/IB2023/062949 WO2024134502A1 (en) | 2022-12-20 | 2023-12-19 | Engineered double-strand rna ligases and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL321537A true IL321537A (he) | 2025-08-01 |
Family
ID=84547245
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL321537A IL321537A (he) | 2022-12-20 | 2025-06-16 | ליגאזות rna דו-גדיליות מהונדסות ושימושיהן |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP4638716A1 (he) |
| JP (1) | JP2025542219A (he) |
| KR (1) | KR20250126043A (he) |
| CN (1) | CN120603936A (he) |
| AR (1) | AR131405A1 (he) |
| AU (1) | AU2023409826A1 (he) |
| IL (1) | IL321537A (he) |
| MX (1) | MX2025007143A (he) |
| TW (1) | TW202440911A (he) |
| WO (1) | WO2024134502A1 (he) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2025262452A1 (en) * | 2024-06-18 | 2025-12-26 | Novartis Ag | Nucleic acid ligation method |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1654354A1 (en) | 2003-08-11 | 2006-05-10 | Codexis, Inc. | Improved ketoreductase polypeptides and related polynucleotides |
| CN1845993B (zh) | 2003-08-28 | 2010-06-23 | 诺瓦提斯公司 | 具有平端和3＇修饰的干扰rna双链体 |
| GB0608838D0 (en) | 2006-05-04 | 2006-06-14 | Novartis Ag | Organic compounds |
| JP7613130B2 (ja) * | 2020-03-25 | 2025-01-15 | 味の素株式会社 | リガーゼ変異体 |
-
2023
- 2023-12-18 AR ARP230103438A patent/AR131405A1/es unknown
- 2023-12-18 TW TW112149321A patent/TW202440911A/zh unknown
- 2023-12-19 JP JP2025535998A patent/JP2025542219A/ja active Pending
- 2023-12-19 KR KR1020257023460A patent/KR20250126043A/ko active Pending
- 2023-12-19 AU AU2023409826A patent/AU2023409826A1/en active Pending
- 2023-12-19 CN CN202380092141.8A patent/CN120603936A/zh active Pending
- 2023-12-19 EP EP23836597.7A patent/EP4638716A1/en active Pending
- 2023-12-19 WO PCT/IB2023/062949 patent/WO2024134502A1/en not_active Ceased
-
2025
- 2025-06-16 IL IL321537A patent/IL321537A/he unknown
- 2025-06-18 MX MX2025007143A patent/MX2025007143A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| TW202440911A (zh) | 2024-10-16 |
| WO2024134502A1 (en) | 2024-06-27 |
| JP2025542219A (ja) | 2025-12-25 |
| CN120603936A (zh) | 2025-09-05 |
| AR131405A1 (es) | 2025-03-19 |
| AU2023409826A1 (en) | 2025-07-03 |
| KR20250126043A (ko) | 2025-08-22 |
| EP4638716A1 (en) | 2025-10-29 |
| MX2025007143A (es) | 2025-07-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL308746A (he) | הרכבי רנ" א מחזוריים ושיטות | |
| EP4164679A4 (en) | IMPROVED IMMUNOGENIC DNA/RNA COMPOSITIONS AND METHODS | |
| EP4045643A4 (en) | CAS12A NUCLEASE VARIANTS AND METHODS OF MAKING AND USING THE SAME | |
| IL318761A (he) | הרכבי אוליגונוקליאוטידים ושיטות שלהם | |
| EP3668972B8 (en) | Engineered dnase enzymes and use in therapy | |
| IL321537A (he) | ליגאזות rna דו-גדיליות מהונדסות ושימושיהן | |
| GB2610711B (en) | Novel engineered and chimeric nucleases | |
| EP1750730A4 (en) | TREATMENT OF HYPERCHOLESTERINEMIA, HYPERTRIGLYCERIDEMIA, AND HEART CIRCUIT-RELATED TREATMENTS USING PHOSPHALIPASE A2 INHIBITORS | |
| IL311625A (he) | הרכבי אוליגונוקלאוטידים ושיטות שלהם | |
| ZA200704821B (en) | Debriding composition from bromelain and methods of production thereof | |
| EP4090752A4 (en) | PLAKOPHILLIN-2 GENE THERAPY METHODS AND COMPOSITIONS | |
| IL325571A (he) | הרכבי אוליגונוקליאוטידים ושיטות שלהם | |
| EP1957064A4 (en) | TREATMENT OF QT INTERVAL EXTENSION AND RELEVANT DISEASES | |
| EP1599172A4 (en) | METHODS FOR THE TREATMENT OF HIV OR MALARIA USING CHLOROQUINE COMBINATIONS AND PROTEASE INHIBITORS | |
| GB2445651B (en) | Well treatment products and methods of using them | |
| IL313573A (he) | וריאנטים sirpα מהונדסים ושיטות לשימוש בהם | |
| IL316714A (he) | קומפוזיציות של אוליגונוקלאוטידים ושיטות לכך | |
| IL318277A (he) | Rna מוצפן ושיטות לשימוש בו | |
| CA3277450A1 (en) | Engineered double-strand rna ligases and uses thereof | |
| HK40129719A (en) | Engineered double-strand rna ligases and uses thereof | |
| ZA202108165B (en) | Application of kdm5a gene and atrx gene | |
| IL326042A (he) | חומרי אוליגונוקלאוטידים דו-גדיליים ושימושים בהם | |
| IL318437A (he) | הרכבים המכילים אוליגונוקלאוטידים, ושיטות לשימוש בהם | |
| GB202306208D0 (en) | Engineered probiotics for expression of fiber-synthesizing enzymes in gut | |
| GB202114871D0 (en) | Guide RNA and uses thereof |