IL320670A - שיטות לשיפור גדילת עצם באמצעות מתן אנטגוניסט il-4r - Google Patents
שיטות לשיפור גדילת עצם באמצעות מתן אנטגוניסט il-4rInfo
- Publication number
- IL320670A IL320670A IL320670A IL32067025A IL320670A IL 320670 A IL320670 A IL 320670A IL 320670 A IL320670 A IL 320670A IL 32067025 A IL32067025 A IL 32067025A IL 320670 A IL320670 A IL 320670A
- Authority
- IL
- Israel
- Prior art keywords
- antagonist
- administering
- methods
- bone growth
- improving bone
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Immunology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Dermatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202263384816P | 2022-11-23 | 2022-11-23 | |
| US202363480717P | 2023-01-20 | 2023-01-20 | |
| US202363498946P | 2023-04-28 | 2023-04-28 | |
| PCT/US2023/080989 WO2024112935A1 (en) | 2022-11-23 | 2023-11-22 | Methods for improving bone growth by administering an il-4r antagonist |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL320670A true IL320670A (he) | 2025-07-01 |
Family
ID=89474536
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL320670A IL320670A (he) | 2022-11-23 | 2023-11-22 | שיטות לשיפור גדילת עצם באמצעות מתן אנטגוניסט il-4r |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP4622669A1 (he) |
| CN (1) | CN120603605A (he) |
| AU (1) | AU2023384154A1 (he) |
| IL (1) | IL320670A (he) |
| MX (1) | MX2025005904A (he) |
| WO (1) | WO2024112935A1 (he) |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2990420B1 (en) | 2000-05-26 | 2016-12-21 | Immunex Corporation | Use of interleukin-4 receptor antibodies and compositions thereof |
| US6596541B2 (en) | 2000-10-31 | 2003-07-22 | Regeneron Pharmaceuticals, Inc. | Methods of modifying eukaryotic cells |
| WO2005047331A2 (en) | 2003-11-07 | 2005-05-26 | Immunex Corporation | Antibodies that bind interleukin-4 receptor |
| US7608693B2 (en) | 2006-10-02 | 2009-10-27 | Regeneron Pharmaceuticals, Inc. | High affinity human antibodies to human IL-4 receptor |
| WO2008054606A2 (en) | 2006-10-02 | 2008-05-08 | Regeneron Pharmaceuticals, Inc. | High affinity human antibodies to human il-4 receptor |
| US8092804B2 (en) | 2007-12-21 | 2012-01-10 | Medimmune Limited | Binding members for interleukin-4 receptor alpha (IL-4Rα)-173 |
| KR101867279B1 (ko) | 2010-10-06 | 2018-06-15 | 리제너론 파아마슈티컬스, 인크. | 항―인터류킨―４ 수용체（ｉｌ－４ｒ） 항체를 함유하는 안정화된 제형 |
| EP2823841A1 (en) | 2013-07-09 | 2015-01-14 | Sanofi-Aventis Deutschland GmbH | Autoinjector |
| TW201707738A (zh) | 2015-06-03 | 2017-03-01 | 賽諾菲阿凡提斯德意志有限公司 | 注射器支架及自動注射器（二） |
| TW201711716A (zh) | 2015-06-03 | 2017-04-01 | 賽諾菲阿凡提斯德意志有限公司 | 護罩鎖 |
| TW201707741A (zh) | 2015-06-03 | 2017-03-01 | 賽諾菲阿凡提斯德意志有限公司 | 針頭護罩之抓握器、蓋子、自動注射器及製造抓握器之方法 |
| TW201709941A (zh) | 2015-06-03 | 2017-03-16 | 賽諾菲阿凡提斯德意志有限公司 | 聲響指示器（二） |
| TW201711713A (zh) | 2015-06-03 | 2017-04-01 | 賽諾菲阿凡提斯德意志有限公司 | 藥物輸送裝置（五） |
| CN113372446A (zh) | 2016-06-08 | 2021-09-10 | 苏州康乃德生物医药有限公司 | 用于结合白细胞介素4受体的抗体 |
| KR102330596B1 (ko) | 2018-11-09 | 2021-11-26 | 아주대학교산학협력단 | 인간 il-4 수용체 알파에 대한 고친화도 인간 항체 및 이의 용도 |
| CN111686247B (zh) | 2019-03-13 | 2022-07-29 | 苏州康乃德生物医药有限公司 | 包含人白介素-4受体α的抗体的液体组合物 |
| CN111592597B (zh) | 2019-05-29 | 2022-04-26 | 山东博安生物技术股份有限公司 | 白介素4受体(il-4r)结合蛋白及其用途 |
| CN113549151A (zh) | 2020-04-24 | 2021-10-26 | 苏州康乃德生物医药有限公司 | 与人IL-4Rα中特定表位结合的抗体及其应用 |
| TW202216782A (zh) | 2020-09-10 | 2022-05-01 | 大陸商舒泰神（北京）生物製藥股份有限公司 | 特異性識別白細胞介素—４受體α的抗體及其用途 |
| EP4267615A1 (en) | 2020-12-23 | 2023-11-01 | Numab Therapeutics AG | Antibody variable domains that bind il-4r |
| EP4019547A1 (en) | 2020-12-23 | 2022-06-29 | Numab Therapeutics AG | Multispecific antibodies having specificity for il-4r and il-31 |
-
2023
- 2023-11-22 IL IL320670A patent/IL320670A/he unknown
- 2023-11-22 AU AU2023384154A patent/AU2023384154A1/en active Pending
- 2023-11-22 WO PCT/US2023/080989 patent/WO2024112935A1/en not_active Ceased
- 2023-11-22 EP EP23836628.0A patent/EP4622669A1/en active Pending
- 2023-11-22 CN CN202380080082.2A patent/CN120603605A/zh active Pending
-
2025
- 2025-05-20 MX MX2025005904A patent/MX2025005904A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2024112935A1 (en) | 2024-05-30 |
| CN120603605A (zh) | 2025-09-05 |
| AU2023384154A1 (en) | 2025-07-03 |
| EP4622669A1 (en) | 2025-10-01 |
| MX2025005904A (es) | 2025-09-02 |
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