IL319556A - Process for creating hyaluronic acid conjugates and hyaluronic acid conjugates formed - Google Patents

Process for creating hyaluronic acid conjugates and hyaluronic acid conjugates formed

Info

Publication number
IL319556A
IL319556A IL319556A IL31955625A IL319556A IL 319556 A IL319556 A IL 319556A IL 319556 A IL319556 A IL 319556A IL 31955625 A IL31955625 A IL 31955625A IL 319556 A IL319556 A IL 319556A
Authority
IL
Israel
Prior art keywords
hyaluronic acid
conjugates
conjugation
hyaluronic
acid
Prior art date
Application number
IL319556A
Other languages
English (en)
Hebrew (he)
Inventor
Giulio Bianchini
Emiliano Esposito
Original Assignee
Glycocore Pharma Srl
Giulio Bianchini
Emiliano Esposito
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glycocore Pharma Srl, Giulio Bianchini, Emiliano Esposito filed Critical Glycocore Pharma Srl
Publication of IL319556A publication Critical patent/IL319556A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0072Hyaluronic acid, i.e. HA or hyaluronan; Derivatives thereof, e.g. crosslinked hyaluronic acid (hylan) or hyaluronates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/549Sugars, nucleosides, nucleotides or nucleic acids
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D15/00Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08Selective adsorption, e.g. chromatography
    • B01D15/26Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/36Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction, e.g. ion-exchange, ion-pair, ion-suppression or ion-exclusion
    • B01D15/361Ion-exchange
    • B01D15/362Cation-exchange
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D61/00Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/24Dialysis ; Membrane extraction
    • B01D61/243Dialysis
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0003General processes for their isolation or fractionation, e.g. purification or extraction from biomass

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Materials Engineering (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Analytical Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Sustainable Development (AREA)
  • Epidemiology (AREA)
  • Water Supply & Treatment (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
IL319556A 2022-09-12 2023-09-08 Process for creating hyaluronic acid conjugates and hyaluronic acid conjugates formed IL319556A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT102022000018585A IT202200018585A1 (it) 2022-09-12 2022-09-12 Procedimento di coniugazione dell’acido ialuronico e coniugati dell’acido ialuronico così ottenuti
PCT/IB2023/058903 WO2024057154A1 (en) 2022-09-12 2023-09-08 Process for conjugation of hyaluronic acid and conjugates of hyaluronic acid so obtained

Publications (1)

Publication Number Publication Date
IL319556A true IL319556A (en) 2025-05-01

Family

ID=84943683

Family Applications (1)

Application Number Title Priority Date Filing Date
IL319556A IL319556A (en) 2022-09-12 2023-09-08 Process for creating hyaluronic acid conjugates and hyaluronic acid conjugates formed

Country Status (8)

Country Link
EP (1) EP4587481A1 (de)
JP (1) JP2025528605A (de)
KR (1) KR20250067823A (de)
CN (1) CN119855838A (de)
CA (1) CA3267508A1 (de)
IL (1) IL319556A (de)
IT (1) IT202200018585A1 (de)
WO (1) WO2024057154A1 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN119548996B (zh) * 2024-12-04 2025-11-04 万华化学集团股份有限公司 一种反渗透元件修复方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3397651B1 (de) * 2015-12-29 2020-05-06 Galderma S.A. Kohlenhydratvernetzer
WO2020129028A1 (en) * 2018-12-21 2020-06-25 Nestlé Skin Health S.A. Hydrogel compositions encapsulating solid particles

Also Published As

Publication number Publication date
IT202200018585A1 (it) 2024-03-12
EP4587481A1 (de) 2025-07-23
CA3267508A1 (en) 2024-03-21
KR20250067823A (ko) 2025-05-15
WO2024057154A1 (en) 2024-03-21
JP2025528605A (ja) 2025-08-28
CN119855838A (zh) 2025-04-18

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