IL318680A - תכשירים רוקחיים ושימושים בהם לטיפול בגליומה - Google Patents

תכשירים רוקחיים ושימושים בהם לטיפול בגליומה

Info

Publication number
IL318680A
IL318680A IL318680A IL31868025A IL318680A IL 318680 A IL318680 A IL 318680A IL 318680 A IL318680 A IL 318680A IL 31868025 A IL31868025 A IL 31868025A IL 318680 A IL318680 A IL 318680A
Authority
IL
Israel
Prior art keywords
glioma
treatment
pharmaceutical compositions
pharmaceutical
compositions
Prior art date
Application number
IL318680A
Other languages
English (en)
Inventor
Joshua Edward Allen
Allen Melemed
Varun Vijay Prabhu
Andrew Kang-Kang Lee
Phiroze Behram Sethna
Original Assignee
Chimerix Inc
Joshua Edward Allen
Allen Melemed
Varun Vijay Prabhu
Lee Andrew Kang Kang
Phiroze Behram Sethna
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chimerix Inc, Joshua Edward Allen, Allen Melemed, Varun Vijay Prabhu, Lee Andrew Kang Kang, Phiroze Behram Sethna filed Critical Chimerix Inc
Publication of IL318680A publication Critical patent/IL318680A/he

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
IL318680A 2022-08-05 2023-08-04 תכשירים רוקחיים ושימושים בהם לטיפול בגליומה IL318680A (he)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202263370520P 2022-08-05 2022-08-05
PCT/US2023/029534 WO2024030645A1 (en) 2022-08-05 2023-08-04 Pharmaceutical compositions and uses thereof for the treatment of glioma

Publications (1)

Publication Number Publication Date
IL318680A true IL318680A (he) 2025-03-01

Family

ID=89849850

Family Applications (1)

Application Number Title Priority Date Filing Date
IL318680A IL318680A (he) 2022-08-05 2023-08-04 תכשירים רוקחיים ושימושים בהם לטיפול בגליומה

Country Status (9)

Country Link
EP (1) EP4565237A4 (he)
JP (1) JP2025527300A (he)
KR (1) KR20250056926A (he)
CN (1) CN119997956A (he)
AU (1) AU2023320122A1 (he)
CA (1) CA3263675A1 (he)
IL (1) IL318680A (he)
MX (1) MX2025001423A (he)
WO (1) WO2024030645A1 (he)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4684834A1 (de) * 2024-07-26 2026-01-28 BRIU GmbH Kristallformen onkologisch wirksamer imipridone und verfahren zu deren herstellung

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2008302345A1 (en) * 2007-09-19 2009-03-26 Oncofluor, Inc. Method for imaging and treating organs and tissues
HUE068623T2 (hu) 2011-04-29 2025-01-28 Penn State Res Found Normál és tumorsejtek kismolekulás TRAIL-génindukclója rákellenes terápiaként
US10172862B2 (en) * 2017-01-30 2019-01-08 Oncoceutics, Inc. Imipridones for gliomas
CA3131740A1 (en) * 2019-02-27 2020-09-03 Madera Therapeutics, LLC Use of caseinolytic protease p function as a biomarker of drug response to imipridone-like agents
CN116437925A (zh) * 2020-08-06 2023-07-14 厄特沃什罗兰科技大学 新的依米立酮衍生物的合成及其抗癌活性的评估
WO2022031952A2 (en) * 2020-08-07 2022-02-10 City Of Hope Treatments for cancers having kras mutations

Also Published As

Publication number Publication date
EP4565237A4 (en) 2026-02-18
WO2024030645A1 (en) 2024-02-08
KR20250056926A (ko) 2025-04-28
MX2025001423A (es) 2025-07-01
AU2023320122A2 (en) 2025-08-14
AU2023320122A1 (en) 2025-02-20
CA3263675A1 (en) 2024-02-08
CN119997956A (zh) 2025-05-13
JP2025527300A (ja) 2025-08-20
EP4565237A1 (en) 2025-06-11

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