IL315898A - Anxiety treatment - Google Patents

Anxiety treatment

Info

Publication number
IL315898A
IL315898A IL315898A IL31589824A IL315898A IL 315898 A IL315898 A IL 315898A IL 315898 A IL315898 A IL 315898A IL 31589824 A IL31589824 A IL 31589824A IL 315898 A IL315898 A IL 315898A
Authority
IL
Israel
Prior art keywords
anxiety
treatment
Prior art date
Application number
IL315898A
Other languages
English (en)
Hebrew (he)
Inventor
Theis Terwey
Conor Burke
Naoise Gaffney
Original Assignee
Gh Res Ireland Limited
Theis Terwey
Conor Burke
Naoise Gaffney
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gh Res Ireland Limited, Theis Terwey, Conor Burke, Naoise Gaffney filed Critical Gh Res Ireland Limited
Publication of IL315898A publication Critical patent/IL315898A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C07D209/16Tryptamines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404Indoles, e.g. pindolol
    • A61K31/4045Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/675Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Psychiatry (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Dispersion Chemistry (AREA)
  • Anesthesiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IL315898A 2022-03-27 2023-03-27 Anxiety treatment IL315898A (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP22000083 2022-03-27
EP22000086 2022-03-27
EP23153995 2023-01-30
EP23153939 2023-01-30
PCT/EP2023/057857 WO2023186816A1 (en) 2022-03-27 2023-03-27 Treatment of anxiety

Publications (1)

Publication Number Publication Date
IL315898A true IL315898A (en) 2024-11-01

Family

ID=86007166

Family Applications (6)

Application Number Title Priority Date Filing Date
IL315898A IL315898A (en) 2022-03-27 2023-03-27 Anxiety treatment
IL315902A IL315902A (en) 2022-03-27 2023-03-27 5-METHOXY-N,N-DIMETHYLTRYPTamine for the treatment of psychomotor retardation
IL315897A IL315897A (en) 2022-03-27 2023-03-27 5-MEO-DMT for use in the treatment of sleep disorders
IL315891A IL315891A (en) 2022-03-27 2023-03-27 5-METHOXY-N,N-DIMETHYLTRYPTamine for the treatment of bipolar disorder
IL315896A IL315896A (en) 2022-03-27 2023-03-27 Cognitive function therapy
IL315899A IL315899A (en) 2022-03-27 2023-03-27 5-METHOXY-N,N-DIMETHYLTRYPTamine for the treatment of social/emotional withdrawal or withdrawal

Family Applications After (5)

Application Number Title Priority Date Filing Date
IL315902A IL315902A (en) 2022-03-27 2023-03-27 5-METHOXY-N,N-DIMETHYLTRYPTamine for the treatment of psychomotor retardation
IL315897A IL315897A (en) 2022-03-27 2023-03-27 5-MEO-DMT for use in the treatment of sleep disorders
IL315891A IL315891A (en) 2022-03-27 2023-03-27 5-METHOXY-N,N-DIMETHYLTRYPTamine for the treatment of bipolar disorder
IL315896A IL315896A (en) 2022-03-27 2023-03-27 Cognitive function therapy
IL315899A IL315899A (en) 2022-03-27 2023-03-27 5-METHOXY-N,N-DIMETHYLTRYPTamine for the treatment of social/emotional withdrawal or withdrawal

Country Status (9)

Country Link
US (9) US20250205199A1 (enExample)
EP (7) EP4499076A1 (enExample)
JP (6) JP2025511081A (enExample)
KR (6) KR20250005181A (enExample)
CN (2) CN119053327A (enExample)
AU (6) AU2023246545A1 (enExample)
CA (6) CA3255505A1 (enExample)
IL (6) IL315898A (enExample)
WO (9) WO2023186797A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3753923A1 (en) 2019-06-19 2020-12-23 GH Research Limited Recrystallisation of 5-methoxy-n,n-dimethyltryptamine (5-meo-dmt) in methyl tert.-butyl ether (mtbe) without adding an anti-solvent
US12534441B2 (en) 2021-01-15 2026-01-27 Beckley Psytech Limited Tryptamine analogues
WO2022153266A1 (en) 2021-01-15 2022-07-21 Beckley Psytech Limited Ergoline analogues
US11312684B1 (en) 2021-02-10 2022-04-26 Eleusis Therapeutics Us, Inc. Pharmaceutically acceptable salts of psilocin and uses thereof
US12264131B2 (en) 2022-08-19 2025-04-01 Beckley Psytech Limited Pharmaceutically acceptable salts and compositions thereof
GB202306256D0 (en) * 2023-04-27 2023-06-14 Beckley Psytech Ltd 5-Methoxy-N,N-Dimethyltryptamine Formulations
US12246005B2 (en) 2023-06-13 2025-03-11 Beckley Psytech Limited 5-methoxy-n,n-dimethyltryptamine (5-MeO-DMT) formulations
WO2026078143A1 (en) 2024-10-09 2026-04-16 GH Research Ireland Limited Combinations of 5-meo-dmt with antidepressants for treating depression

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19803376C1 (de) 1998-01-29 1999-10-14 Markus Storz Inhalator zur Erzeugung von aroma- und/oder wirkstoffhaltigen Dämpfen aus Pflanzenmaterial und/oder Flüssigkeiten
US7458374B2 (en) 2002-05-13 2008-12-02 Alexza Pharmaceuticals, Inc. Method and apparatus for vaporizing a compound
US7766013B2 (en) 2001-06-05 2010-08-03 Alexza Pharmaceuticals, Inc. Aerosol generating method and device
US20040234699A1 (en) 2003-05-21 2004-11-25 Alexza Molecular Delivery Corporation Methods of controlling uniformity of substrate temperature and self-contained heating unit and drug-supply unit employing same
ATE489981T1 (de) 2006-08-01 2010-12-15 Stobi Gmbh & Co Kg Ventilballon für inhalatoren
EP3713568A1 (en) * 2017-10-26 2020-09-30 Consejo Superior de Investigaciones Cientificas (CSIC) Combination product for the treatment of neurological and/or psychiatric disorders
AU2020225766B2 (en) * 2019-02-22 2025-10-30 GH Research Ireland Limited Compositions comprising 5-Methoxy-N,N-dimethyltryptamine (5-MeO-DMT) for use in treating mental disorders
EA202192318A1 (ru) 2019-02-22 2021-12-21 Гх Рисерч Айрленд Лимитед 5-метокси-n,n-диметилтриптамин (5-meo-dmt) для лечения депрессии
JP2022529781A (ja) * 2019-04-17 2022-06-24 コンパス パスファインダー リミテッド サイロシビンによるうつ病及び他の様々な障害の治療
EP3868364A1 (en) * 2020-02-24 2021-08-25 GH Research Limited Aerosol comprising 5-methoxy-n,n-dimethyltryptamine
WO2021216489A1 (en) * 2020-04-20 2021-10-28 Lobe Sciences Ltd. Methods for treating mild traumatic brain injury, post traumatic stress disorder and mild traumatic brain injury
KR20230024378A (ko) * 2020-06-12 2023-02-20 벡클리 싸이테크 리미티드 5-메톡시-n, n-디메틸트립타민의 벤조에이트 염을 포함하는 조성물
US11406619B2 (en) * 2020-08-28 2022-08-09 Small Pharma Ltd Injectable formulations
WO2022189662A1 (en) 2021-03-12 2022-09-15 Alvarius Pharmaceuticals Ltd. Compositions and methods for treating addictions comprising 5-meo-dmt

Also Published As

Publication number Publication date
JP2025510368A (ja) 2025-04-14
US20250205199A1 (en) 2025-06-26
CA3255340A1 (en) 2023-10-05
US20250241891A1 (en) 2025-07-31
EP4499226A1 (en) 2025-02-05
EP4499073A1 (en) 2025-02-05
WO2023186816A1 (en) 2023-10-05
WO2023186806A1 (en) 2023-10-05
EP4499075A1 (en) 2025-02-05
CA3255629A1 (en) 2023-10-05
CN119053327A (zh) 2024-11-29
KR20250005181A (ko) 2025-01-09
CA3255348A1 (en) 2023-10-05
KR20240167879A (ko) 2024-11-28
IL315891A (en) 2024-11-01
AU2023246543A1 (en) 2024-11-07
EP4499088A1 (en) 2025-02-05
WO2023186823A1 (en) 2023-10-05
EP4499076A1 (en) 2025-02-05
JP2025510912A (ja) 2025-04-15
US20250213532A1 (en) 2025-07-03
US20240108602A1 (en) 2024-04-04
CA3255648A1 (en) 2023-10-05
IL315897A (en) 2024-11-01
JP2025510369A (ja) 2025-04-14
AU2023242291A1 (en) 2024-11-07
AU2023246679A1 (en) 2024-11-07
AU2023246774A1 (en) 2024-11-07
JP2025511081A (ja) 2025-04-15
KR20250005176A (ko) 2025-01-09
WO2023186830A1 (en) 2023-10-05
CN119095595A (zh) 2024-12-06
KR20250005170A (ko) 2025-01-09
CA3255343A1 (en) 2023-10-05
EP4499083A1 (en) 2025-02-05
US20250241892A1 (en) 2025-07-31
US20240108601A1 (en) 2024-04-04
CA3255505A1 (en) 2023-10-05
KR20250005179A (ko) 2025-01-09
AU2023246545A1 (en) 2024-11-07
WO2023186797A1 (en) 2023-10-05
WO2023186820A1 (en) 2023-10-05
US20250241893A1 (en) 2025-07-31
WO2023186835A1 (en) 2023-10-05
US20250241895A1 (en) 2025-07-31
WO2023186826A1 (en) 2023-10-05
US20250205256A1 (en) 2025-06-26
IL315899A (en) 2024-11-01
JP2025512831A (ja) 2025-04-22
IL315896A (en) 2024-11-01
JP2025510916A (ja) 2025-04-15
WO2023186829A1 (en) 2023-10-05
AU2023244452A1 (en) 2024-11-07
IL315902A (en) 2024-11-01
KR20250005183A (ko) 2025-01-09
EP4499082A1 (en) 2025-02-05

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