IL31444A - Pesticidal preparations containing trifluoromethyl-phenyl-(thio)ureas and certain new such compounds - Google Patents

Pesticidal preparations containing trifluoromethyl-phenyl-(thio)ureas and certain new such compounds

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Publication number
IL31444A
IL31444A IL31444A IL3144469A IL31444A IL 31444 A IL31444 A IL 31444A IL 31444 A IL31444 A IL 31444A IL 3144469 A IL3144469 A IL 3144469A IL 31444 A IL31444 A IL 31444A
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IL
Israel
Prior art keywords
compound
composition according
active ingredient
compounds
group
Prior art date
Application number
IL31444A
Other versions
IL31444A0 (en
Original Assignee
Ciba Geigy Ag
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Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of IL31444A0 publication Critical patent/IL31444A0/en
Publication of IL31444A publication Critical patent/IL31444A/en

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/20Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
    • C07D295/215Radicals derived from nitrogen analogues of carbonic acid
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/28Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C275/32Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by singly-bound oxygen atoms
    • C07C275/34Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by singly-bound oxygen atoms having nitrogen atoms of urea groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/64Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups singly-bound to oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/23Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C323/39Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton at least one of the nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom
    • C07C323/43Y being a hetero atom
    • C07C323/44X or Y being nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C335/00Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C335/04Derivatives of thiourea
    • C07C335/16Derivatives of thiourea having nitrogen atoms of thiourea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C335/18Derivatives of thiourea having nitrogen atoms of thiourea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by singly-bound oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D203/00Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D203/04Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D203/06Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D203/16Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with acylated ring nitrogen atoms
    • C07D203/20Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with acylated ring nitrogen atoms by carbonic acid, or by sulfur or nitrogen analogues thereof, e.g. carbamates
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D265/00Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/041,3-Oxazines; Hydrogenated 1,3-oxazines
    • C07D265/061,3-Oxazines; Hydrogenated 1,3-oxazines not condensed with other rings

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Description

preparations containing and certain new euoh oompounde AO Oi29736 2 The present invention provides herbicidal positions which as active at least one compound of the general formula in which X and represents an oxygen or a sulphur represents a or methoxy grou phenyl group which may he or by or or phon lalkyl group having 1 to carbon atoms in the alkyl and represents hydrogen or a alkyl or and together with nitrogen atom to they are attached form a to 7 saturated monocyclic heterocycle or a or pholino and an alkoxyalkyl or alkylthioalkyl group with 1 to 4 carbon atoms in eaoh alkyl together with a suitable The new preparations may contain one or more o the following a a a an a an adhesive and other pesticidal Israeli Patent Specification 21685 discloses anthelmintic urea and thiourea derivatives in which one of the phenyl rings carries a trifluoromethyl 5 in each case possibly with a further of a primary amino group further in the phenyl to obtain the desired phenylurea formula The new compounds above a selective activity against weeds in cultures of useful This activity can be produced by the and post method and is primarily observed in important scale cultures for example soybeans or A total herbicidal activity is produced when applying larger amounts of the This is always advantageous when the cultured soil is to be prepared for fresh while residues of a previous still remain in Some of the compounds act also as When used in very minor the new phenylureas display a good microbicidal activity against bacteria and for example against Aspergillus Staphylococcus Escherichia coli or Rhizoctonia for which purpose the compounds and 24 in the following Table I are especially They also display good activity against for example Alternaria tenuis or Alternaria solani or against the soil fungus which can be especially successfully combated with the compound Compound 9 for fu thermore displays a chemosterilizing action against The new ureas of the formula I may be formulated into pesticidal preparations in dry or liquid form as Specification 3 British 1 047 and Swiss In many it is advantageous to use granulates to ensure that the active substance is given off uniformly over a prolonged period of Such granulates can be prepared by dissolving the active substance in an organic absorbing this solution a granulated for example attapulgite or and removing the Whatever form of application of the preparations is it may be distributed dusting or the over a large area by The various forms of application of such preparations can be adapted to the particular use by admixture of known substances that improve the stability to rain and possibly the such substances for fatty wetting casein or For the manufacture of herbicidal numerous components may further be The most important of these are mentioned dimethylurea trichloroacetic 2 2 3 2 2 isopropylcarbanilate acid and salts different sodium sodium chlorate and sulphamic The preparations of this invention may also be used in combination with fungicides or The following Examples illustrate the the parts being by EXAMPLE 1 A solution of 33 parts of phenylisocyanate in 50 cc of acetonitrile is added drop by drop to a solution of 20 cc of dimethylamine aqueous in 100 cc of whilst vigorously The reaction product is precipitated with water and filtered it melts at In an identical manner the following compounds were TABLE 1 R 86 89 o 129 oil 16 89 then also the following Compound Compound 0 124 of finely divided Si02 marketed under the trade name of a condensation product of 1 mol of with 12 moles of ethylene oxide of a condensation product of with 9 nols of ethylene The finely ground mixture can be diluted with water in any desired proportion to form a spray broth ready for EXAMPLE 3 In a greenhouse earthenware pots were filled with earth and seeded with several of the following kinds of Triticum Hordeum Beta Sinapis Lepidium Cynodon Galium and The post emergent treatment of the plants mentioned was carried out with a and an aqueous solution of one of the compounds described in Example 1 some 10 to 12 days after in the leaf in an amount of 2 kg of active substance per Evaluation was carried out about 20 days after the treatment and revealed the results shown in Table The treatment was carried out with the same amount of active substance before 24 hours after seedinga 1 plant at most only slightly affected 4 6 medium damage 7 8 heavy damage 9 plant From the test it is seen that compounds 1 and 24 are suitable for use as weed control agents in wheat cultures both in the pre and the Oompoundo havo a broador they and also tolerates but destroy the weeds whioh Compound 24 is a typical selective herbicide for the protection of cotton cultures by the pre Compound 26 is suitable as a weed control agent in maize it is especially advantageous in cases where the application of triazine derivatives over many years have failed to destroy all the because types of weeds that had once been unimportant have now come into the and are hardly attacked by EXAMPLE 4 A special field test in which compound 1 was teste in winter wheat revealed the following results During tillering in a field of winter whea was treated with 1 kg of active substance per the field was infested with the natural weeds Poa Apera Stellaria and The evaluation was carried out namely after 4 and 8 weeks and revealed that all weed mentioned had been EXAMPLE 5 The new ureas and thioureas of the formula have a strong action against especially against staphylococci and The antibacterial activity in the dilution test was determined as Bacteriostasis 20 mg of active substance are dissolved in 1 0 ml of ml of this solution is added to ml of sterile glucose broth and then further diluted in the tubes 1 1 These solutions are then inoculated with Staphylococcus aureus and incubated for 48 hours at After this the following values in ppm inhibitory of the effect were Compound aureus Bakteriostasis 3 5 6 17 5 EXAMPLE 6 In a greenhouse e pots were filled with earth and seeded with the following kinds of The reatment of the plants mentioned was carried out with a aqueous solution of each the pounds 2 to 29 described in Example some 10 to 12 days after in the leaf an amount of 2 kg of active substance per Evaluation was carried out about 20 days the treatment and svealed the results shown in Table The treatment was oarried out with the same amount of active substance before 24 hours after 1 3 plant at most only slightly affected medium damage 7 8 heavy damage 18 t 19 insufficientOCRQuality

Claims (8)

1. Herbicidal compositions which contain as active ingredient, at least one compound of the general formula in which X and Y eaoh represents an oxygen or a sulphur atom; R. represents a CL-C. alkyl* allyl, 2-me hylpropynyl, 2,2- dimethoxyethyl or methoxy group, a phenyl group which may be mono- or disubstltuted by . chlorine, -CF^, -CH^ or -OCH^; or v ■ «eie4¾H and Rg represents hydroge or a C^- ^ aikyl group,, or R^ and Rg together with the nitrogen atom to which they are attached form a 3 to 7 membered saturated monocyclic hetero- cycle or a morpholino, methylmorpholino or dimethylmorpholino group; and a kenyl» an alkoxyalkyl or alkylthioalkyl group with 1 to 4 carbon alaas in each alkyl moiety, together with a suitable carrier.
2. A Composition according to Claim 1, wherein there is alap present one or more of the following additives: a vehicle a solvent, a diluent, a dispersant, an emulsi ier, a wetting agent, an adhesive or further pesticidal agents.
3. Compounds of the formula I in Claim 1, in which X, Y, g and ^ have the same meaning as in Claim 1 and ^ represent a O^-C^ alkyl, allyl, 2-methylpropynyl, 2, 2~diraetnpxyethyV»/ or 31444/3 - 21 -
4. 8. Th© compound of the formula 0 CH2CH2-0-C2H5 Compounds according to Claim 3 and substantially described in Example 1 herein. 31444/2 j - 22 - AV. A composition acoording to Olaim 1 or 2, wherein the active ingredient is a compound as claimed in Claim 3* ti» A composition according to Claim 1 or 2, wherein the active ingredient is a compound as claimed in Claim 4· A composition according to Claim 1 or 2, wherein the active ingredient is a compound as claimed in Claim
5. A composition according to Claim 1 or 2, wherein the active ingredient is the compound as claimed in Claim
6. A composition according to Claim 1 or 2, wherein the active Ingredient is a compound as claimed in Claim 7* $» A composition according to Claim 1 or.2, wherein the active ingredient is the compound as claimed in Claim 8. ti* A composition according to Claim 1 and substantially as described in any one of Examples 2 - 6 herein. %$* A method of selectively, treating weeds in a crop area which oomprlses applying to the crop area a compound according to Claim 3, using either the pre-emergent or post-emergent process* %· A method of selectively treating weds in a cro area, which comprises applying to the crop area a composition according to Olaim 1, using either the pre-emergent or post-emergent process. 7 8 2*0· A method according to Claim 1$ or 1 , wherein the crop area contains cereals, rice, maize, soybeans or cotton. 31444/3 - 23 -
20. A method of controlling phytopathogenic fungi and "bacteria, which comprises applying thereto a compound according to Claim 3.
21. . A method of controlling phytopathogenic fungi and bacteria, which comprises applying thereto a composition according to Claim 1, For the Applicants ND/ru
IL31444A 1968-01-23 1969-01-19 Pesticidal preparations containing trifluoromethyl-phenyl-(thio)ureas and certain new such compounds IL31444A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH102268A CH493195A (en) 1968-01-23 1968-01-23 Pesticides

Publications (2)

Publication Number Publication Date
IL31444A0 IL31444A0 (en) 1969-03-27
IL31444A true IL31444A (en) 1973-03-30

Family

ID=4200614

Family Applications (1)

Application Number Title Priority Date Filing Date
IL31444A IL31444A (en) 1968-01-23 1969-01-19 Pesticidal preparations containing trifluoromethyl-phenyl-(thio)ureas and certain new such compounds

Country Status (15)

Country Link
BE (1) BE727286A (en)
BG (1) BG17267A3 (en)
CH (1) CH493195A (en)
CS (1) CS158236B2 (en)
DE (1) DE1901501C3 (en)
DK (1) DK124443B (en)
FR (1) FR2000570A1 (en)
GB (1) GB1260386A (en)
IE (1) IE32624B1 (en)
IL (1) IL31444A (en)
NL (1) NL159091B (en)
RO (1) RO54785A (en)
SE (1) SE375095B (en)
SU (1) SU404191A3 (en)
YU (1) YU34874B (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3222974A1 (en) * 1982-06-19 1983-12-22 Basf Ag, 6700 Ludwigshafen NEW 5-PHENOXYBENZISOTHIAZOL-4'-UREA DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE AS HERBICIDES
EP0427963B1 (en) * 1989-11-10 1994-03-30 Agrolinz Agrarchemikalien Gesellschaft M.B.H. Process for the preparation of pure asymmetric disubstituted urea
DE10029564A1 (en) 2000-06-22 2002-01-03 Continental Ag elastomeric bearings
AU2003243921B2 (en) 2002-06-27 2009-05-07 Novo Nordisk A/S Aryl carbonyl derivatives as therapeutic agents
WO2005066145A1 (en) 2004-01-06 2005-07-21 Novo Nordisk A/S Heteroaryl-ureas and their use as glucokinase activators
ES2382815T3 (en) 2005-07-08 2012-06-13 Novo Nordisk A/S Dicycloalkylcarbamoyl ureas as glucokinase activators
US7884210B2 (en) 2005-07-14 2011-02-08 Novo Nordisk A/S Ureido-thiazole glucokinase activators
US8138185B2 (en) 2007-01-09 2012-03-20 Novo Nordisk A/S Urea glucokinase activators
US8318778B2 (en) 2007-01-11 2012-11-27 Novo Nordisk A/S Urea glucokinase activators
KR20210020866A (en) 2018-06-12 2021-02-24 브이티브이 테라퓨틱스 엘엘씨 The therapeutic use of glucokinase activators in combination with insulin or insulin analogues
WO2021167840A1 (en) 2020-02-18 2021-08-26 Vtv Therapeutics Llc Sulfoxide and sulfone glucokinase activators and methods of use thereof
EP4161640A4 (en) 2020-06-08 2024-01-17 vTv Therapeutics LLC SALTS OR COCRYSTALS OF {2-[3-CYCLOHEXYL-3-(TRANS-4-PROPOXY-CYCLOHEXYL)-UREIDO)-THIAZOLE-5-YLSULFANYL}-ACETIC ACID AND USES THEREOF

Also Published As

Publication number Publication date
IE32624L (en) 1969-07-23
YU15469A (en) 1979-10-31
CH493195A (en) 1970-07-15
YU34874B (en) 1980-04-30
NL6901066A (en) 1969-07-25
IE32624B1 (en) 1973-10-03
NL159091B (en) 1979-01-15
SU404191A3 (en) 1973-10-26
DK124443B (en) 1972-10-23
RO54785A (en) 1973-05-17
BG17267A3 (en) 1973-07-25
FR2000570A1 (en) 1969-09-12
CS158236B2 (en) 1974-10-15
DE1901501A1 (en) 1969-08-28
DE1901501B2 (en) 1977-09-22
DE1901501C3 (en) 1978-05-03
IL31444A0 (en) 1969-03-27
BE727286A (en) 1969-07-22
SE375095B (en) 1975-04-07
GB1260386A (en) 1972-01-19

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