IL312885A - Nitroxoline for use in the treatment or prevention of flexiform neurofibroma - Google Patents

Nitroxoline for use in the treatment or prevention of flexiform neurofibroma

Info

Publication number
IL312885A
IL312885A IL312885A IL31288524A IL312885A IL 312885 A IL312885 A IL 312885A IL 312885 A IL312885 A IL 312885A IL 31288524 A IL31288524 A IL 31288524A IL 312885 A IL312885 A IL 312885A
Authority
IL
Israel
Prior art keywords
nitroxoline
prevention
treatment
plexiform neurofibroma
plexiform
Prior art date
Application number
IL312885A
Other languages
English (en)
Hebrew (he)
Inventor
David Brown
Original Assignee
Healx Ltd
David Brown
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Healx Ltd, David Brown filed Critical Healx Ltd
Publication of IL312885A publication Critical patent/IL312885A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL312885A 2021-11-19 2022-11-18 Nitroxoline for use in the treatment or prevention of flexiform neurofibroma IL312885A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB2116743.2A GB202116743D0 (en) 2021-11-19 2021-11-19 Treatment
PCT/GB2022/052933 WO2023089328A1 (en) 2021-11-19 2022-11-18 Nitroxoline for use in the treatment or prevention of a plexiform neurofibroma

Publications (1)

Publication Number Publication Date
IL312885A true IL312885A (en) 2024-07-01

Family

ID=79163954

Family Applications (1)

Application Number Title Priority Date Filing Date
IL312885A IL312885A (en) 2021-11-19 2022-11-18 Nitroxoline for use in the treatment or prevention of flexiform neurofibroma

Country Status (11)

Country Link
US (1) US20250000852A1 (enExample)
EP (1) EP4433054B1 (enExample)
JP (1) JP2024540439A (enExample)
KR (1) KR20240108407A (enExample)
CN (1) CN118215479A (enExample)
AU (1) AU2022392456A1 (enExample)
CA (1) CA3238805A1 (enExample)
GB (1) GB202116743D0 (enExample)
IL (1) IL312885A (enExample)
MX (1) MX2024006105A (enExample)
WO (1) WO2023089328A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB202218460D0 (en) * 2022-12-08 2023-01-25 Healx Ltd Treatment
WO2026022492A1 (en) * 2024-07-26 2026-01-29 Healx Limited Nitroxoline for use in the treatment and/or prevention of pain

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102239149B (zh) * 2008-10-06 2015-05-13 约翰·霍普金斯大学 喹啉化合物作为血管新生、人类甲硫氨酰氨肽酶、以及sirt1的抑制剂,以及治疗病症的方法
GB202108224D0 (en) * 2021-06-09 2021-07-21 Healx Ltd Treatment

Also Published As

Publication number Publication date
MX2024006105A (es) 2024-05-30
CA3238805A1 (en) 2023-05-25
CN118215479A (zh) 2024-06-18
EP4433054B1 (en) 2026-07-08
JP2024540439A (ja) 2024-10-31
EP4433054A1 (en) 2024-09-25
AU2022392456A1 (en) 2024-05-23
WO2023089328A1 (en) 2023-05-25
KR20240108407A (ko) 2024-07-09
GB202116743D0 (en) 2022-01-05
US20250000852A1 (en) 2025-01-02

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