IL302948A - תכשירים למתן מעכבים של cgrp - Google Patents

תכשירים למתן מעכבים של cgrp

Info

Publication number
IL302948A
IL302948A IL302948A IL30294823A IL302948A IL 302948 A IL302948 A IL 302948A IL 302948 A IL302948 A IL 302948A IL 30294823 A IL30294823 A IL 30294823A IL 302948 A IL302948 A IL 302948A
Authority
IL
Israel
Prior art keywords
pharmaceutical composition
composition according
cgrp
weight
alkyl glycoside
Prior art date
Application number
IL302948A
Other languages
English (en)
Inventor
Charles M Conway
Gene M Dubowchik
Rajesh Kumar
Original Assignee
Pfizer Ireland Pharmaceuticals
Charles M Conway
Gene M Dubowchik
Rajesh Kumar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Ireland Pharmaceuticals, Charles M Conway, Gene M Dubowchik, Rajesh Kumar filed Critical Pfizer Ireland Pharmaceuticals
Publication of IL302948A publication Critical patent/IL302948A/he

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • A61K9/2018Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/2063Proteins, e.g. gelatin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Pain & Pain Management (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Hydrogenated Pyridines (AREA)
IL302948A 2020-11-19 2021-11-18 תכשירים למתן מעכבים של cgrp IL302948A (he)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063115789P 2020-11-19 2020-11-19
US202063126550P 2020-12-17 2020-12-17
PCT/US2021/059801 WO2022109077A1 (en) 2020-11-19 2021-11-18 Compositions for improved delivery of cgrp inhibitors

Publications (1)

Publication Number Publication Date
IL302948A true IL302948A (he) 2023-07-01

Family

ID=81709748

Family Applications (1)

Application Number Title Priority Date Filing Date
IL302948A IL302948A (he) 2020-11-19 2021-11-18 תכשירים למתן מעכבים של cgrp

Country Status (9)

Country Link
EP (1) EP4247364A4 (he)
JP (1) JP2023551146A (he)
KR (1) KR20230088442A (he)
AU (1) AU2021385052A1 (he)
CA (1) CA3202137A1 (he)
IL (1) IL302948A (he)
MX (1) MX2023005846A (he)
WO (1) WO2022109077A1 (he)
ZA (1) ZA202304727B (he)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115154469A (zh) * 2022-07-22 2022-10-11 中国科学院广州生物医药与健康研究院 瑞美吉泮或其药学上可接受的盐在制备预防或治疗肥胖的药物中的应用
CN117503704B (zh) * 2023-11-09 2025-07-11 广州新济药业科技有限公司 一种作用于中枢神经系统的鼻喷雾剂及其制备方法及应用

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8268791B2 (en) * 2004-08-25 2012-09-18 Aegis Therapeutics, Llc. Alkylglycoside compositions for drug administration
US8715715B2 (en) * 2008-11-03 2014-05-06 Nal Pharmaceuticals Ltd. Dosage form for insertion into the mouth
US8481546B2 (en) * 2010-03-30 2013-07-09 Bristol-Myers Squibb Company CGRP receptor antagonist
JP6491669B2 (ja) * 2014-02-05 2019-03-27 メルク・シャープ・アンド・ドーム・コーポレーションMerck Sharp & Dohme Corp. Cgrp活性化合物の錠剤製剤
US20160346198A1 (en) * 2014-02-05 2016-12-01 Merck Sharp & Dohme Corp. Novel disintegration systems for pharmaceutical dosage forms
EP3426288A4 (en) * 2016-04-15 2019-10-30 Alder Biopharmaceuticals, Inc. ANTI-PACAP ANTIBODIES AND USES THEREOF
SI4088720T1 (sl) * 2018-03-25 2026-01-30 Pfizer Ireland Pharmaceuticals Unlimited Company Rimegepant za motnje, povezane s cgrp
JP2022517433A (ja) * 2019-01-20 2022-03-08 バイオヘイブン・ファーマシューティカル・ホールディング・カンパニー・リミテッド 突出性の片頭痛を処置するためのcgrpアンタゴニスト
BR112021018817A2 (pt) * 2019-04-11 2021-11-23 Scherer Technologies Llc R P Formulação para suprimento oral de proteínas, peptídeos e moléculas pequenas com pouca permeabilidade
WO2020232379A1 (en) * 2019-05-16 2020-11-19 Aegis Therapeutics, Llc Oil-soluble drug containing compositions and methods of use thereof
CA3156009A1 (en) * 2019-09-25 2021-04-01 Allergan Pharmaceuticals International Limited POLYTHERAPY WITH CGRP ANTAGONISTS
CA3164445A1 (en) * 2019-12-17 2021-06-24 Biohaven Pharmaceutical Holding Company Ltd. Intranasal pharmaceutical compositions of cgrp inhibitors

Also Published As

Publication number Publication date
EP4247364A4 (en) 2024-10-23
MX2023005846A (es) 2023-06-02
WO2022109077A1 (en) 2022-05-27
EP4247364A1 (en) 2023-09-27
AU2021385052A9 (en) 2024-05-02
CA3202137A1 (en) 2022-05-27
ZA202304727B (en) 2023-12-20
AU2021385052A1 (en) 2023-06-01
JP2023551146A (ja) 2023-12-07
KR20230088442A (ko) 2023-06-19

Similar Documents

Publication Publication Date Title
JP5752048B2 (ja) 薬物投与のための組成物
US10512694B2 (en) Compositions for oral drug administration
US8440631B2 (en) Compositions for drug administration
IL303817A (he) תכשירים להעברה משופרת של מעכבי cgrp
US20090047347A1 (en) Compositions for Drug Administration
IL302948A (he) תכשירים למתן מעכבים של cgrp
US20110046058A1 (en) Compositions for enteral absorption and sustained action of leptin-related peptides useful in the treatment of obesity and leptin-modulated disease
US20180000942A1 (en) Compositions for drug administration
HK40096688A (zh) 用於cgrp抑制剂的改善的递送的组合物
WO2012066347A1 (en) Oil based formulations
HK1164059B (en) Compositions for drug administration