IL291105B1 - Neurosleeve for closed loop emg-fes based control of pathological tremors - Google Patents
Neurosleeve for closed loop emg-fes based control of pathological tremorsInfo
- Publication number
- IL291105B1 IL291105B1 IL291105A IL29110522A IL291105B1 IL 291105 B1 IL291105 B1 IL 291105B1 IL 291105 A IL291105 A IL 291105A IL 29110522 A IL29110522 A IL 29110522A IL 291105 B1 IL291105 B1 IL 291105B1
- Authority
- IL
- Israel
- Prior art keywords
- electrodes
- tremor
- anatomical
- tremors
- nmes
- Prior art date
Links
- 206010044565 Tremor Diseases 0.000 title claims 28
- 230000001575 pathological effect Effects 0.000 title 1
- 210000003484 anatomy Anatomy 0.000 claims 13
- 230000006870 function Effects 0.000 claims 10
- 238000002567 electromyography Methods 0.000 claims 8
- 230000001629 suppression Effects 0.000 claims 8
- 210000003423 ankle Anatomy 0.000 claims 6
- 210000000707 wrist Anatomy 0.000 claims 6
- 210000002683 foot Anatomy 0.000 claims 3
- 238000010801 machine learning Methods 0.000 claims 3
- 238000013528 artificial neural network Methods 0.000 claims 2
- 238000001914 filtration Methods 0.000 claims 2
- 230000005012 migration Effects 0.000 claims 2
- 238000013508 migration Methods 0.000 claims 2
- 230000002232 neuromuscular Effects 0.000 claims 2
- 230000003595 spectral effect Effects 0.000 claims 2
- 230000000638 stimulation Effects 0.000 claims 2
- 230000002747 voluntary effect Effects 0.000 claims 2
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/0404—Electrodes for external use
- A61N1/0408—Use-related aspects
- A61N1/0452—Specially adapted for transcutaneous muscle stimulation [TMS]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
- A61B5/25—Bioelectric electrodes therefor
- A61B5/279—Bioelectric electrodes therefor specially adapted for particular uses
- A61B5/296—Bioelectric electrodes therefor specially adapted for particular uses for electromyography [EMG]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/0404—Electrodes for external use
- A61N1/0408—Use-related aspects
- A61N1/0456—Specially adapted for transcutaneous electrical nerve stimulation [TENS]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/0404—Electrodes for external use
- A61N1/0472—Structure-related aspects
- A61N1/0476—Array electrodes (including any electrode arrangement with more than one electrode for at least one of the polarities)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/0404—Electrodes for external use
- A61N1/0472—Structure-related aspects
- A61N1/0484—Garment electrodes worn by the patient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/36003—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation of motor muscles, e.g. for walking assistance
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/36014—External stimulators, e.g. with patch electrodes
- A61N1/3603—Control systems
- A61N1/36031—Control systems using physiological parameters for adjustment
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
- A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
- A61N1/36067—Movement disorders, e.g. tremor or Parkinson disease
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Biophysics (AREA)
- Heart & Thoracic Surgery (AREA)
- Physiology (AREA)
- Physical Education & Sports Medicine (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Surgery (AREA)
- Pathology (AREA)
- Hospice & Palliative Care (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Medical Informatics (AREA)
- Electrotherapy Devices (AREA)
- Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
- Magnetic Treatment Devices (AREA)
- Prostheses (AREA)
- Eye Examination Apparatus (AREA)
Description
291105/2
.
Claims (11)
- 291105/ Claims 1. A tremor suppression device comprising: a garment wearable on an anatomical region and including electrodes contacting the anatomical region when the garment is worn on the anatomical region and further including at least one inertial motion unit (IMU); and an electronic controller configured to: detect electromyography (EMG) signals as a function of anatomical location and time using the electrodes; determine an orientation of the anatomical region using the at least one IMU; identify tremors as a function of anatomical location and time based on the EMG signals; determine tremor suppressing neuromuscular electrical stimulation (NMES) at one or more anatomical locations as a function of time by inputting the identified tremors and the orientation of the anatomical region to an artificial neural network (ANN); and apply the tremor suppressing NMES at one or more anatomical locations as a function of time using the electrodes to suppress the identified tremors.
- 2. The tremor suppression device of claim 1, wherein the electronic controller is configured to identify tremors by operations including spectral filtering the EMG signals to remove frequency components corresponding to voluntary motion.
- 3. The tremor suppression device of claim 1, wherein the electronic controller is configured to identify tremors further based on the orientation of the anatomical region determined using the IMU. 291105/
- 4. The tremor suppression device of claim 1, wherein the garment is a sleeve and the anatomical region is an arm, a leg, a wrist, an ankle, an arm and a wrist, or a leg and an ankle.
- 5. The tremor suppression device of claim 1, wherein the anatomical region is an arm, a leg, a wrist, an ankle, a hand, a foot, an arm and a wrist, a leg and an ankle, an arm and a wrist and a hand, a leg and an ankle and a foot, a wrist and a hand, or an ankle and a foot.
- 6. The tremor suppression device of claim 1, wherein the electrodes comprise electrogel.
- 7. The tremor suppression device of claim 1, wherein one of: (i) the electrodes consist of a single set of electrodes that is used to both detect the EMG signals and apply the NMES; or (ii) the electrodes comprise a first set of electrodes that is used to detect the EMG signals and a second set of electrodes that is used to apply the NMES.
- 8. A device providing feedback-controlled neuromuscular electrical stimulation (NMES) for tremor suppression, the device comprising: electrodes; and an electronic controller that in conjunction with the electrodes performs a feedback loop comprising: receiving electromyography (EMG) signals from an anatomical region via the electrodes as a function of anatomical location and time; identifying tremors as a function of anatomical location and time based on the received EMG signals; determining tremor suppressing NMES as a function of anatomical location and time by inputting the identified tremors as a function of anatomical location and time to a machine learning (ML) component; 291105/ applying, via the electrodes, the tremor suppressing NMES as a function of anatomical location and time; determining updated tremor suppressing NMES that is updated for expected tremor migration by inputting both the identified tremors as a function of anatomical location and time and the applied tremor suppressing NMES to the ML component; and applying, via the electrodes, the updated tremor suppressing NMES that is updated for the expected tremor migration.
- 9. The device of claim 8, wherein the identifying of the tremors includes spectral filtering the received EMG signals to remove frequency components corresponding to voluntary motion.
- 10. The device of claim 8, further comprising at least one inertial motion unit (IMU), wherein the identifying of the tremors is further based on an orientation of the anatomical region determined using the at least one IMU.
- 11. The device of claim 8 further comprising: a garment wearable on the anatomical region and including the electrodes contacting the anatomical region when the garment is worn on the anatomical region.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962868158P | 2019-06-28 | 2019-06-28 | |
| PCT/US2020/039802 WO2020264280A1 (en) | 2019-06-28 | 2020-06-26 | Neurosleeve for closed loop emg-fes based control of pathological tremors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL291105A IL291105A (en) | 2022-05-01 |
| IL291105B1 true IL291105B1 (en) | 2024-05-01 |
Family
ID=74044233
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL291105A IL291105B1 (en) | 2019-06-28 | 2020-06-26 | Neurosleeve for closed loop emg-fes based control of pathological tremors |
| IL289399A IL289399B2 (en) | 2019-06-28 | 2021-12-26 | Neurosleeve for closed loop emg-fes based control of pathological tremors |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL289399A IL289399B2 (en) | 2019-06-28 | 2021-12-26 | Neurosleeve for closed loop emg-fes based control of pathological tremors |
Country Status (5)
| Country | Link |
|---|---|
| US (3) | US11160971B2 (en) |
| EP (1) | EP3990098A1 (en) |
| BR (1) | BR112021026669A2 (en) |
| CA (1) | CA3144964A1 (en) |
| IL (2) | IL291105B1 (en) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3352843B1 (en) | 2015-09-23 | 2021-06-23 | Cala Health, Inc. | Device for peripheral nerve stimulation in the finger to treat hand tremors |
| IL286747B2 (en) | 2016-01-21 | 2024-05-01 | Cala Health Inc | Wearable device for treating urinary symptoms |
| EP3740274A4 (en) | 2018-01-17 | 2021-10-27 | Cala Health, Inc. | Systems and methods for treating inflammatory bowel disease through peripheral nerve stimulation |
| US11701293B2 (en) | 2018-09-11 | 2023-07-18 | Encora, Inc. | Apparatus and method for reduction of neurological movement disorder symptoms using wearable device |
| BR112021026669A2 (en) * | 2019-06-28 | 2022-02-15 | Battelle Memorial Institute | Neurosleeve for closed-loop emg-fes-based control of pathological tremors |
| US11766191B2 (en) * | 2019-06-28 | 2023-09-26 | Battelle Memorial Institute | Neurosleeve for closed loop EMG-FES based control of pathological tremors |
| US11890468B1 (en) | 2019-10-03 | 2024-02-06 | Cala Health, Inc. | Neurostimulation systems with event pattern detection and classification |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20150290451A1 (en) * | 2012-12-05 | 2015-10-15 | Battelle Memorial Institute | Neuromuscular stimulation cuff |
| US9452287B2 (en) * | 2013-01-21 | 2016-09-27 | Cala Health, Inc. | Devices and methods for controlling tremor |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8112155B2 (en) | 2004-02-05 | 2012-02-07 | Motorika Limited | Neuromuscular stimulation |
| US7643882B2 (en) | 2005-05-24 | 2010-01-05 | Leon Boston | Tremor reduction systems suitable for self-application and use in disabled patients |
| US20070012395A1 (en) | 2005-07-15 | 2007-01-18 | Tuertscher Jennifer L | Methods involving processing of a continuous web at a desired location in relationship to the actual location of a discrete part |
| US20100174342A1 (en) | 2006-11-26 | 2010-07-08 | Leon Boston | Tremor reduction systems suitable for self-application and use in disabled patients |
| WO2009051638A1 (en) | 2007-10-16 | 2009-04-23 | Medtronic, Inc. | Therapy control based on a patient movement state |
| US9884179B2 (en) | 2012-12-05 | 2018-02-06 | Bbattelle Memorial Institute | Neural sleeve for neuromuscular stimulation, sensing and recording |
| EP4108292A1 (en) | 2013-05-08 | 2022-12-28 | Consejo Superior De Investigaciones Científicas (CSIC) | Method and neuroprosthetic device for monitoring and suppression of pathological tremors through neurostimulation of the afferent pathways |
| US10437335B2 (en) | 2015-04-14 | 2019-10-08 | John James Daniels | Wearable electronic, multi-sensory, human/machine, human/human interfaces |
| WO2018098046A2 (en) | 2016-11-25 | 2018-05-31 | Kinaptic, LLC | Haptic human machine interface and wearable electronics methods and apparatus |
| US11058352B2 (en) | 2017-11-16 | 2021-07-13 | Klick Inc. | Electrical stimulation facilitated symptom transference for empathic response |
| WO2019126080A1 (en) | 2017-12-18 | 2019-06-27 | Dan Sachs | Devices, systems and methods for therapeutic muscle stimulation |
| BR112021026669A2 (en) * | 2019-06-28 | 2022-02-15 | Battelle Memorial Institute | Neurosleeve for closed-loop emg-fes-based control of pathological tremors |
| US11766191B2 (en) * | 2019-06-28 | 2023-09-26 | Battelle Memorial Institute | Neurosleeve for closed loop EMG-FES based control of pathological tremors |
-
2020
- 2020-06-26 BR BR112021026669A patent/BR112021026669A2/en unknown
- 2020-06-26 IL IL291105A patent/IL291105B1/en unknown
- 2020-06-26 CA CA3144964A patent/CA3144964A1/en active Pending
- 2020-06-26 EP EP20743421.8A patent/EP3990098A1/en active Pending
- 2020-08-25 US US17/002,135 patent/US11160971B2/en active Active
-
2021
- 2021-09-16 US US17/476,723 patent/US11642513B2/en active Active
- 2021-12-26 IL IL289399A patent/IL289399B2/en unknown
-
2023
- 2023-04-04 US US18/130,488 patent/US11911604B2/en active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20150290451A1 (en) * | 2012-12-05 | 2015-10-15 | Battelle Memorial Institute | Neuromuscular stimulation cuff |
| US9452287B2 (en) * | 2013-01-21 | 2016-09-27 | Cala Health, Inc. | Devices and methods for controlling tremor |
Also Published As
| Publication number | Publication date |
|---|---|
| US11642513B2 (en) | 2023-05-09 |
| CA3144964A1 (en) | 2020-12-30 |
| US11911604B2 (en) | 2024-02-27 |
| IL289399A (en) | 2022-02-01 |
| US20220001164A1 (en) | 2022-01-06 |
| BR112021026669A2 (en) | 2022-02-15 |
| IL291105A (en) | 2022-05-01 |
| US20230233843A1 (en) | 2023-07-27 |
| IL289399B2 (en) | 2023-02-01 |
| EP3990098A1 (en) | 2022-05-04 |
| US11160971B2 (en) | 2021-11-02 |
| IL289399B (en) | 2022-10-01 |
| US20200406022A1 (en) | 2020-12-31 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL291105B1 (en) | Neurosleeve for closed loop emg-fes based control of pathological tremors | |
| US11484710B2 (en) | Device and system for real-time gait modulation and methods of operation thereof | |
| ATE429949T1 (en) | NEUROMUSCULAR STIMULATION | |
| Bo et al. | FES-induced co-activation of antagonist muscles for upper limb control and disturbance rejection | |
| DE112013005623T5 (en) | Adaptive exoskeleton, devices and methods for controlling the same | |
| Rocon et al. | Biomechanical loading as an alternative treatment for tremor: a review of two approaches | |
| WO2008062395A1 (en) | Tremor reduction systems suitable for self-application and use in disabled patients | |
| DE202015005645U1 (en) | Functional clothing with tactile stimulus module and EMG electrode | |
| Dideriksen et al. | A model of the surface electromyogram in pathological tremor | |
| Eggers et al. | Model-based Bayesian signal extraction algorithm for peripheral nerves | |
| Müller et al. | Iterative learning control and system identification of the antagonistic knee muscle complex during gait using functional electrical stimulation | |
| Jiang et al. | Myoelectric control in neurorehabilitation | |
| Gandolla et al. | EMG-controlled robotic hand rehabilitation device for domestic training | |
| Kim et al. | Real-time motion artifact detection and removal for ambulatory BCI | |
| Li et al. | A hybrid functional electrical stimulation for real-time estimation of joint torque and closed-loop control of muscle activation | |
| Huo et al. | Adaptive fes assistance using a novel gait phase detection approach | |
| EP4010063B1 (en) | Neurosleeve for tuning tremor supression using electrical stimulation by vagus nerve stimulation or direct brain stimulation | |
| JP2021514774A (en) | Non-invasive nerve stimulation | |
| Salchow-Hömmen et al. | Adaptive hand neuroprosthesis using inertial sensors for real-time motion tracking | |
| Salchow et al. | Development of a feedback-controlled hand neuroprosthesis: FES-supported mirror training | |
| de Melo | A novel functional electrical stimulation system and strategies for motor rehabilitation | |
| WO2020264280A1 (en) | Neurosleeve for closed loop emg-fes based control of pathological tremors | |
| Vlutters et al. | Are Ankle Muscle Responses in Balance Recovery Hard-Wired? | |
| Wang et al. | Active tracking movements of flexion and extension on the elbow joint for an initial prototype of EMG-driven assistant exoskeleton | |
| Schauer et al. | Gait training by FES |