IL285483A - Methods for treating chronic sinusitis with nasal polyps by administering an il-4r antagonist - Google Patents

Methods for treating chronic sinusitis with nasal polyps by administering an il-4r antagonist

Info

Publication number
IL285483A
IL285483A IL285483A IL28548321A IL285483A IL 285483 A IL285483 A IL 285483A IL 285483 A IL285483 A IL 285483A IL 28548321 A IL28548321 A IL 28548321A IL 285483 A IL285483 A IL 285483A
Authority
IL
Israel
Prior art keywords
antagonist
administering
methods
treating chronic
chronic sinusitis
Prior art date
Application number
IL285483A
Other languages
Hebrew (he)
Other versions
IL285483B (en
Original Assignee
Regeneron Pharma
Sanofi Biotechnology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Regeneron Pharma, Sanofi Biotechnology filed Critical Regeneron Pharma
Priority claimed from PCT/US2015/060540 external-priority patent/WO2016077675A1/en
Publication of IL285483A publication Critical patent/IL285483A/en
Publication of IL285483B publication Critical patent/IL285483B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/48Other medical applications
    • A61B5/4848Monitoring or testing the effects of treatment, e.g. of medication
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0043Nose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/02Nasal agents, e.g. decongestants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/54Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/545Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Otolaryngology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Medical Informatics (AREA)
  • Hematology (AREA)
  • Surgery (AREA)
  • Transplantation (AREA)
  • Physics & Mathematics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
IL285483A 2014-11-14 2015-11-13 Methods for treating chronic sinusitis with nasal polyps by administering an il-4r antagonist IL285483B (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201462080092P 2014-11-14 2014-11-14
US201462083821P 2014-11-24 2014-11-24
US201562158832P 2015-05-08 2015-05-08
US201562199305P 2015-07-31 2015-07-31
EP15306632 2015-10-14
PCT/US2015/060540 WO2016077675A1 (en) 2014-11-14 2015-11-13 Methods for treating chronic sinusitis with nasal polyps by administering an il-4r antagonist

Publications (2)

Publication Number Publication Date
IL285483A true IL285483A (en) 2021-09-30
IL285483B IL285483B (en) 2022-08-01

Family

ID=71117011

Family Applications (2)

Application Number Title Priority Date Filing Date
IL285483A IL285483B (en) 2014-11-14 2015-11-13 Methods for treating chronic sinusitis with nasal polyps by administering an il-4r antagonist
IL277362A IL277362B (en) 2014-11-14 2020-09-15 Methods for treating chronic sinusitis with nasal polyps by administering an il-4r antagonist

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL277362A IL277362B (en) 2014-11-14 2020-09-15 Methods for treating chronic sinusitis with nasal polyps by administering an il-4r antagonist

Country Status (3)

Country Link
JP (1) JP7216122B2 (en)
HK (1) HK1243716A1 (en)
IL (2) IL285483B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10066017B2 (en) * 2014-11-14 2018-09-04 Sanofi Biotechnology Methods for treating chronic sinusitis with nasal polyps by administering an IL-4R antagonist
CN116203244B (en) * 2022-03-30 2025-06-27 首都医科大学附属北京同仁医院 A kit for non-invasive diagnosis of type 2 chronic sinusitis with nasal polyps

Also Published As

Publication number Publication date
IL277362A (en) 2020-11-30
HK1243716A1 (en) 2018-07-20
IL277362B (en) 2021-08-31
IL285483B (en) 2022-08-01
JP7216122B2 (en) 2023-01-31
JP2021063122A (en) 2021-04-22

Similar Documents

Publication Publication Date Title
IL303337B2 (en) Methods for treating chronic sinusitis with nasal polyps by administering an il-4r antagonist
PT3613432T (en) Methods for treating nasal polyposis by administering an il-4r antagonist
PT3973987T (en) Methods for treating or preventing asthma by administering an il-4r antagonist
PT3110483T (en) Inhaler
PT3020430T (en) Cannula for catgut-embedding therapy
EP3125821C0 (en) INSERT FOR AN INHALER
DK3215223T3 (en) BUPRENORPHIN DOSAGE SCHEMES
ZA201608785B (en) Nasal administration
IL285483A (en) Methods for treating chronic sinusitis with nasal polyps by administering an il-4r antagonist
AU358579S (en) Inhaler
SG10201912898XA (en) Methods for treating nasal polyposis by administering an il-4r antagonist
SG11201700059WA (en) Therapeutic agent for keratoconjunctive disorder
GB201409603D0 (en) An inhalable medicament
IL247290A0 (en) Methods for treating or preventing asthma by administering an il-4r antagonist
CA3249780A1 (en) Methods for treating or preventing asthma by administering an il-4r antagonist
IL249533A0 (en) Treatment for chronic lymphocytic leukemia (cll)
AU367030S (en) Nasal interface
HK1236855A1 (en) Nasal administration
GB201508562D0 (en) Inhaler
PH32014001154S1 (en) Inhaler
PH32014000866S1 (en) Inhaler
PH32014000796S1 (en) Inhaler
PH32014000795S1 (en) Inhaler
PH32014000794S1 (en) Inhaler
PH32014000334S1 (en) Inhaler