IL276467A - Manufacturing method for nucleic acid molecule - Google Patents
Manufacturing method for nucleic acid moleculeInfo
- Publication number
- IL276467A IL276467A IL276467A IL27646720A IL276467A IL 276467 A IL276467 A IL 276467A IL 276467 A IL276467 A IL 276467A IL 27646720 A IL27646720 A IL 27646720A IL 276467 A IL276467 A IL 276467A
- Authority
- IL
- Israel
- Prior art keywords
- manufacturing
- nucleic acid
- acid molecule
- molecule
- nucleic
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title 1
- 150000007523 nucleic acids Chemical class 0.000 title 1
- 102000039446 nucleic acids Human genes 0.000 title 1
- 108020004707 nucleic acids Proteins 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/111—General methods applicable to biologically active non-coding nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
- C12P19/28—N-glycosides
- C12P19/30—Nucleotides
- C12P19/34—Polynucleotides, e.g. nucleic acids, oligoribonucleotides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/93—Ligases (6)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/14—Type of nucleic acid interfering N.A.
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/30—Chemical structure
- C12N2310/31—Chemical structure of the backbone
- C12N2310/318—Chemical structure of the backbone where the PO2 is completely replaced, e.g. MMI or formacetal
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/50—Physical structure
- C12N2310/53—Physical structure partially self-complementary or closed
- C12N2310/531—Stem-loop; Hairpin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2330/00—Production
- C12N2330/30—Production chemically synthesised
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y605/00—Ligases forming phosphoric ester bonds (6.5)
- C12Y605/01—Ligases forming phosphoric ester bonds (6.5) forming phosphoric ester bonds (6.5.1)
- C12Y605/01003—RNA ligase (ATP) (6.5.1.3)
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2018021799 | 2018-02-09 | ||
PCT/JP2019/003827 WO2019156020A1 (en) | 2018-02-09 | 2019-02-04 | Manufacturing method for nucleic acid molecule |
Publications (1)
Publication Number | Publication Date |
---|---|
IL276467A true IL276467A (en) | 2020-09-30 |
Family
ID=67549590
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL276467A IL276467A (en) | 2018-02-09 | 2020-08-03 | Manufacturing method for nucleic acid molecule |
Country Status (8)
Country | Link |
---|---|
US (1) | US20210040525A1 (en) |
EP (1) | EP3751004A4 (en) |
JP (3) | JP6701459B2 (en) |
KR (1) | KR20200120634A (en) |
CN (1) | CN111684073B (en) |
IL (1) | IL276467A (en) |
TW (1) | TWI830718B (en) |
WO (1) | WO2019156020A1 (en) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TWI830718B (en) * | 2018-02-09 | 2024-02-01 | 日商住友化學股份有限公司 | Method of producing nucleic acid molecule |
US11920131B2 (en) * | 2018-03-30 | 2024-03-05 | Toray Industries, Inc. | Method of producing hairpin single-stranded RNA molecule |
WO2021024467A1 (en) * | 2019-08-08 | 2021-02-11 | 住友化学株式会社 | Production method for single-strand rna |
JP6828219B1 (en) * | 2019-08-08 | 2021-02-10 | 住友化学株式会社 | Nucleic acid molecule manufacturing method |
Family Cites Families (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3687808A (en) | 1969-08-14 | 1972-08-29 | Univ Leland Stanford Junior | Synthetic polynucleotides |
US5959090A (en) | 1996-07-02 | 1999-09-28 | Glen Research Corporation | Chemical phosphorylation of oligonucleotides and reactants used therefor |
PT1196637E (en) * | 1999-07-27 | 2007-07-04 | Adnexus Therapeutics Inc | Peptide acceptor ligation methods |
US8242058B2 (en) * | 2006-07-21 | 2012-08-14 | Wisconsin Alumni Research Foundation | Reagents and methods for appending functional groups to proteins |
US8383370B2 (en) * | 2007-01-30 | 2013-02-26 | The Rockefeller University | Modified RNA ligase for efficient 3′ modification of RNA |
JP5540312B2 (en) * | 2008-02-15 | 2014-07-02 | 独立行政法人理化学研究所 | Circular single-stranded nucleic acid complex and method for producing the same |
JPWO2011052013A1 (en) * | 2009-10-29 | 2013-03-14 | 株式会社バイオダイナミクス研究所 | Nucleic acid chain binding and modification methods |
US9145556B2 (en) * | 2010-04-13 | 2015-09-29 | Life Technologies Corporation | Compositions and methods for inhibition of nucleic acids function |
WO2012005368A1 (en) * | 2010-07-08 | 2012-01-12 | 株式会社ボナック | Single-strand nucleic acid molecule for controlling gene expression |
DK2674494T3 (en) * | 2010-08-03 | 2015-02-23 | Bonac Corp | Single-stranded RNA molecule with a nitrogen-containing alicyclic skeleton |
EP2749565B1 (en) | 2011-08-25 | 2017-05-31 | Bonac Corporation | Nucleoside phosphoramidates for producing nucleic acids |
ES2645996T3 (en) | 2012-01-07 | 2017-12-11 | Bonac Corporation | Single stranded nucleic acid molecule that has a main amino acid chain |
EP2824184B1 (en) * | 2012-03-04 | 2017-09-27 | Bonac Corporation | micro-RNA INHIBITOR |
US10597650B2 (en) * | 2012-12-21 | 2020-03-24 | New England Biolabs, Inc. | Ligase activity |
WO2014110272A1 (en) * | 2013-01-09 | 2014-07-17 | The Penn State Research Foundation | Low sequence bias single-stranded dna ligation |
WO2015093495A1 (en) * | 2013-12-16 | 2015-06-25 | 株式会社ボナック | Single-stranded nucleic acid molecule for controlling expression of tgf-β1 gene |
WO2015099122A1 (en) * | 2013-12-26 | 2015-07-02 | 学校法人東京医科大学 | Artificial mimic mirna for controlling gene expression, and use of same |
US10934542B2 (en) * | 2013-12-27 | 2021-03-02 | Bonac Corporation | Artificial match-type miRNA for controlling gene expression and use therefor |
WO2016010047A1 (en) * | 2014-07-18 | 2016-01-21 | 国立大学法人東京大学 | Method for detecting nucleic acid, capture probe, detection probe set, microarray, nucleic acid detection kit, nucleic-acid-immobilized solid phase, and fluid device |
US11027023B2 (en) * | 2014-12-27 | 2021-06-08 | Bonac Corporation | Natural type miRNA for controlling gene expression, and use of same |
ES2926369T3 (en) * | 2015-03-27 | 2022-10-25 | Bonac Corp | Single-stranded nucleic acid molecule that has a delivery function and ability to control gene expression |
JP6609637B2 (en) * | 2015-10-30 | 2019-11-20 | 株式会社ボナック | Composition comprising a single-stranded nucleic acid molecule that suppresses the expression of TGF-β1 gene stably |
JP6438440B2 (en) | 2016-08-02 | 2018-12-12 | 旭化成エレクトロニクス株式会社 | Hall sensor and method for adjusting hall sensor |
TWI830718B (en) * | 2018-02-09 | 2024-02-01 | 日商住友化學股份有限公司 | Method of producing nucleic acid molecule |
-
2019
- 2019-02-01 TW TW108104031A patent/TWI830718B/en active
- 2019-02-04 KR KR1020207023269A patent/KR20200120634A/en active Search and Examination
- 2019-02-04 WO PCT/JP2019/003827 patent/WO2019156020A1/en unknown
- 2019-02-04 JP JP2019562665A patent/JP6701459B2/en active Active
- 2019-02-04 CN CN201980011729.XA patent/CN111684073B/en active Active
- 2019-02-04 EP EP19751298.1A patent/EP3751004A4/en active Pending
- 2019-02-04 US US16/967,643 patent/US20210040525A1/en active Pending
-
2020
- 2020-05-01 JP JP2020081423A patent/JP6864767B2/en active Active
- 2020-08-03 IL IL276467A patent/IL276467A/en unknown
-
2021
- 2021-01-15 JP JP2021005326A patent/JP2021072813A/en active Pending
Also Published As
Publication number | Publication date |
---|---|
JP2021072813A (en) | 2021-05-13 |
KR20200120634A (en) | 2020-10-21 |
JPWO2019156020A1 (en) | 2020-06-25 |
JP6701459B2 (en) | 2020-05-27 |
EP3751004A1 (en) | 2020-12-16 |
JP6864767B2 (en) | 2021-04-28 |
EP3751004A4 (en) | 2022-03-30 |
CN111684073A (en) | 2020-09-18 |
WO2019156020A1 (en) | 2019-08-15 |
TW202003844A (en) | 2020-01-16 |
CN111684073B (en) | 2024-01-05 |
TWI830718B (en) | 2024-02-01 |
JP2020182461A (en) | 2020-11-12 |
US20210040525A1 (en) | 2021-02-11 |
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