IL274162A - Selenogalactoside compounds for the treatment of systemic insulin resistance disorders and the use thereof - Google Patents

Selenogalactoside compounds for the treatment of systemic insulin resistance disorders and the use thereof

Info

Publication number
IL274162A
IL274162A IL274162A IL27416220A IL274162A IL 274162 A IL274162 A IL 274162A IL 274162 A IL274162 A IL 274162A IL 27416220 A IL27416220 A IL 27416220A IL 274162 A IL274162 A IL 274162A
Authority
IL
Israel
Prior art keywords
selenogalactoside
compounds
treatment
insulin resistance
systemic insulin
Prior art date
Application number
IL274162A
Other languages
Hebrew (he)
Original Assignee
Galectin Sciences Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Galectin Sciences Llc filed Critical Galectin Sciences Llc
Publication of IL274162A publication Critical patent/IL274162A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/056—Triazole or tetrazole radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/7056—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing five-membered rings with nitrogen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/80—Polymers containing hetero atoms not provided for in groups A61K31/755 - A61K31/795
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H5/00—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
    • C07H5/08—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to sulfur, selenium or tellurium

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
IL274162A 2017-10-31 2020-04-23 Selenogalactoside compounds for the treatment of systemic insulin resistance disorders and the use thereof IL274162A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762579343P 2017-10-31 2017-10-31
PCT/US2018/032321 WO2019089080A1 (en) 2017-10-31 2018-05-11 Selenogalactoside compounds for the treatment of systemic insulin resistance disorders and the use thereof

Publications (1)

Publication Number Publication Date
IL274162A true IL274162A (en) 2020-06-30

Family

ID=66332241

Family Applications (1)

Application Number Title Priority Date Filing Date
IL274162A IL274162A (en) 2017-10-31 2020-04-23 Selenogalactoside compounds for the treatment of systemic insulin resistance disorders and the use thereof

Country Status (8)

Country Link
EP (1) EP3707149A1 (en)
JP (1) JP2021501180A (en)
KR (1) KR20200081443A (en)
CN (1) CN111527097A (en)
AU (1) AU2018361991A1 (en)
CA (1) CA3080128A1 (en)
IL (1) IL274162A (en)
WO (1) WO2019089080A1 (en)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3475706B1 (en) * 2016-06-27 2021-08-11 Juno Therapeutics, Inc. Mhc-e restricted epitopes, binding molecules and related methods and uses
EP3658172A4 (en) 2017-07-25 2021-05-05 TrueBinding, Inc. CANCER TREATMENT BY BLOCKING THE INTERACTION OF TIM-3 AND ITS LIGAND
CN113711036B (en) 2019-01-30 2025-03-18 真和制药有限公司 Anti-GAL3 antibodies and uses thereof
ES2974680T3 (en) 2019-08-09 2024-07-01 Idorsia Pharmaceuticals Ltd Derivatives of (2-acetamidyl)thio-beta-D-galactopyranosides
US12404295B2 (en) 2019-08-09 2025-09-02 Idorsia Pharmaceuticals Ltd (Hetero)aryl-methyl-thio-beta-D-galactopyranoside derivatives
UA128909C2 (en) 2019-08-15 2024-11-20 Ідорсія Фармасьютікалз Лтд 2-HYDROXYCYCLOALKANE-1-CARBAMOYL DERIVATIVES
PH12022550436A1 (en) * 2019-08-29 2022-12-19 Idorsia Pharmaceuticals Ltd Alpha-d-galactopyranoside derivatives
JP7835441B2 (en) * 2019-12-06 2026-03-25 トゥルーバインディング,インコーポレイテッド Antibodies that interfere with the interaction between GAL3 and insulin receptors or integrins, and methods for using them.
CN116157151A (en) 2020-05-26 2023-05-23 真和制药有限公司 Methods of treating inflammatory diseases by blocking galectin-3
AU2021356076A1 (en) 2020-10-06 2023-06-08 Idorsia Pharmaceuticals Ltd Spiro derivatives of alpha-d-galactopyranosides
IL302421A (en) 2020-11-02 2023-06-01 Idorsia Pharmaceuticals Ltd 2-Hydroxycycloalkane-1-carbamoyl compounds inhibit galectin-3
CN112190590A (en) * 2020-11-06 2021-01-08 牡丹江医学院 Selenium nucleoside for treating atherosclerosis and pharmaceutical composition thereof
JP7844491B2 (en) 2021-02-09 2026-04-13 イドルシア・ファーマシューティカルズ・リミテッド Hydroxyheterocycloalkane-carbamoyl derivatives
EP4301748B1 (en) 2021-03-03 2025-05-07 Idorsia Pharmaceuticals Ltd Triazolyl-methyl substituted alpha-d-galactopyranoside derivatives
JP1763359S (en) 2023-09-08 2024-02-13
WO2025084276A1 (en) * 2023-10-16 2025-04-24 Cyn-Kバイオ株式会社 Treatment of obesity
JP1779661S (en) 2024-05-09 2024-09-11
JP1779660S (en) 2024-05-09 2024-09-11

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3250581B1 (en) * 2015-01-30 2021-01-20 Galecto Biotech AB Alpha-d-galactoside inhibitors of galectins
CN105318222B (en) * 2015-11-13 2018-07-27 南通亚泰蜡业工艺品有限公司 Fountain electric candle
JP7086008B2 (en) * 2016-03-04 2022-06-17 ガレクティン・サイエンシーズ・リミテッド・ライアビリティ・カンパニー Serenogalactoside compounds and their use for the prevention and treatment of galactin-related diseases

Also Published As

Publication number Publication date
EP3707149A1 (en) 2020-09-16
CA3080128A1 (en) 2019-05-09
WO2019089080A9 (en) 2020-07-23
WO2019089080A1 (en) 2019-05-09
KR20200081443A (en) 2020-07-07
CN111527097A (en) 2020-08-11
JP2021501180A (en) 2021-01-14
AU2018361991A1 (en) 2020-05-14

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